AutismKB 2.0

Annotation Detail for FGFR2


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Basic Information Top
Gene Symbol:FGFR2 ( BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25 )
Gene Full Name: fibroblast growth factor receptor 2
Band: 10q26.13
Quick LinksEntrez ID:2263; OMIM: 176943; Uniprot ID:FGFR2_HUMAN; ENSEMBL ID: ENSG00000066468; HGNC ID: 3689
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
83N-linked (GlcNAc...) (Potential).
123N-linked (GlcNAc...) (Potential).
228N-linked (GlcNAc...) (Potential).
241N-linked (GlcNAc...) (Potential).
265N-linked (GlcNAc...) (Potential).
297N-linked (GlcNAc...) (Potential).
318N-linked (GlcNAc...) (Potential).
331N-linked (GlcNAc...) (Potential).
448Phosphothreonine.
449Phosphothreonine.
657Phosphotyrosine; by autocatalysis (By
Location(AA) Modifications Resource
83N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
123N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
228N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
241N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
265N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
297N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
318N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
331N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
657Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
769PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
45Phosphoserine(ATM)HMM predict
50Phosphotyrosine(EGFR)HMM predict
83N-linkedHMM predict
105Phosphotyrosine(INSR)HMM predict
112Phosphothreonine(PKC)HMM predict
123N-linkedHMM predict
129Phosphoserine(CK2)HMM predict
174Phosphothreonine(PKC)HMM predict
188Phosphothreonine(PKC)HMM predict
228N-linkedHMM predict
229Phosphotyrosine(INSR)HMM predict
237Phosphotyrosine(INSR)HMM predict
237Phosphotyrosine(SRC)HMM predict
237Phosphotyrosine(EGFR)HMM predict
241N-linkedHMM predict
297N-linkedHMM predict
318N-linkedHMM predict
331N-linkedHMM predict
340Phosphotyrosine(INSR)HMM predict
402N-linkedHMM predict
411Phosphoserine(IKK)HMM predict
429Phosphothreonine(PKC)HMM predict
429Phosphothreonine(PKA)HMM predict
434Phosphoserine(CK2)HMM predict
435O-linkedHMM predict
437Phosphoserine(IKK)HMM predict
452Phosphoserine(CK2)HMM predict
453Phosphoserine(PKB)HMM predict
466Phosphotyrosine(INSR)HMM predict
529Phosphoserine(CK1)HMM predict
681Phosphothreonine(CDK)HMM predict
727N-linkedHMM predict
730N-linkedHMM predict
733PhosphotyrosineHMM predict
733Phosphotyrosine(INSR)HMM predict
769PhosphotyrosineHMM predict
769Phosphotyrosine(Syk)HMM predict
773Phosphoserine(ATM)HMM predict
786O-linkedHMM predict
788Phosphoserine(IKK)HMM predict
792Phosphoserine(IKK)HMM predict
792Phosphoserine(CK1)HMM predict
799Phosphoserine(CDC2)HMM predict
799Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022970
  • Location:chr10 123227845-123347961
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 123358229 123358383 154 10345
CTCF CD4SISSRdata 123358229 123358383 154 10345
CTCF JurkatGSE12889 123358270 123358405 135 10376
hScc1 BcellGSE12603 123357951 123359181 1230 10605
hScc1 CdLSGSE12603 123358125 123358635 510 10419
p63 keratinocytesGSE17611 123360168 123361143 975 12694
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
RNAII Tamoxifen-MCF7GSE14664 123208793 123208828 35 19035
RNAII Tamoxifen-MCF7GSE14664 123208884 123208921 37 18943
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 123259325 123260213 888 0
ER MCF7GSE19013 123305821 123306323 502 0
FOXA1 MCF7GSE15244 123261433 123262001 568 0
FoxA1 MCF7MACSdata 123261603 123261779 176 0
FoxA1 MCF7MACSdata 123292326 123292577 251 0
FoxA1 MCF7MACSdata 123304430 123304630 200 0
Nanog hESGSE18292 123302777 123303363 586 0
Nanog hESGSE18292 123339407 123340138 731 0
Oct1 HelaGSE14283 123232542 123232583 41 0
PAX3-FKHR Rh4GSE19063 123249924 123250910 986 0
RARA MCF7GSE15244 123259287 123260257 970 0
RARA MCF7GSE15244 123261255 123262001 746 0
RARA MCF7GSE15244 123263892 123265075 1183 0
RARA MCF7GSE15244 123292155 123292682 527 0
RARA MCF7GSE15244 123302141 123303805 1664 0
RARA MCF7GSE15244 123304226 123304553 327 0
RARG MCF7GSE15244 123245432 123246028 596 0
RARG MCF7GSE15244 123259287 123260257 970 0
RARG MCF7GSE15244 123261183 123262228 1045 0
RARG MCF7GSE15244 123264003 123265036 1033 0
RARG MCF7GSE15244 123292116 123292647 531 0
RARG MCF7GSE15244 123302105 123303805 1700 0
STAT1 HeLaGSE12782 123259001 123260713 1712 0
STAT1 HeLaGSE12783 123259013 123262012 2999 0
STAT1 IFNSISSRdata 123259184 123260338 1154 0
TFAP2C MCF7GSE21234 123259576 123260439 863 0
TFAP2C MCF7GSE21234 123303281 123303809 528 0
TFAP2C MCF7GSE21234 123304228 123304775 547 0
TFAP2C MCF7GSE21234 123329783 123330737 954 0
hScc1 BcellGSE12603 123346604 123347276 672 0
p63 keratinocytesGSE17611 123346256 123347488 1232 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-494 hsa-mir-494 14 20837890
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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