AutismKB 2.0

Annotation Detail for FGFR4


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Basic Information Top
Gene Symbol:FGFR4 ( CD334,JTK2,MGC20292,TKF )
Gene Full Name: fibroblast growth factor receptor 4
Band: 5q35.2
Quick LinksEntrez ID:2264; OMIM: 134935; Uniprot ID:FGFR4_HUMAN; ENSEMBL ID: ENSG00000160867; HGNC ID: 3691
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
112N-linked (GlcNAc...) (Potential).
258N-linked (GlcNAc...) (Potential).
290N-linked (GlcNAc...) (Potential).
311N-linked (GlcNAc...) (Potential).
322N-linked (GlcNAc...) (Potential).
573Phosphoserine.
643Phosphotyrosine; by autocatalysis (By
Location(AA) Modifications Resource
112N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
258N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
290N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
311N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
322N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
643Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
754Phosphotyrosine (FGFR4)Phospho.ELM 6.0
Location(AA) Modification Resource
112N-linkedHMM predict
124Phosphoserine(CK2)HMM predict
137PhosphoserineHMM predict
167Phosphothreonine(PKC)HMM predict
177N-linkedHMM predict
179Phosphothreonine(MAPK)HMM predict
181Phosphothreonine(PKC)HMM predict
222Phosphotyrosine(INSR)HMM predict
258N-linkedHMM predict
290N-linkedHMM predict
311N-linkedHMM predict
312Phosphoserine(CK1)HMM predict
331Phosphotyrosine(INSR)HMM predict
419Phosphoserine(CK1)HMM predict
425Phosphoserine(ATM)HMM predict
431Phosphoserine(CK1)HMM predict
439Phosphoserine(PKG)HMM predict
547Phosphotyrosine(Abl)HMM predict
573Phosphoserine(ATM)HMM predict
667Phosphothreonine(CDK)HMM predict
700Phosphoserine(CK1)HMM predict
719Phosphotyrosine(SRC)HMM predict
731Phosphoserine(ATM)HMM predict
754PhosphotyrosineHMM predict
773Phosphoserine(IKK)HMM predict
780Phosphoserine(ATM)HMM predict
780O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002011
  • Location:chr5 176446526-176457729
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 176441588 176442011 423 4727
KLF4 hESGSE17917 176446176 176446676 500 101
TFAP2C MCF7GSE21234 176445668 176446303 635 541
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 176446606 176446815 209 0
CTCF CD4SISSRdata 176446606 176446815 209 0
CTCF G2GSE9613 176446195 176447385 1190 0
H3ac HepG2E 176447311 176447607 296 0
H3ac HepG2E 176447975 176449913 1938 0
Validated miRNA targets Top
Cis-Nats regulation Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018