AutismKB 2.0

Annotation Detail for FGG


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Basic Information Top
Gene Symbol:FGG ( - )
Gene Full Name: fibrinogen gamma chain
Band: 4q32.1
Quick LinksEntrez ID:2266; OMIM: 134850; Uniprot ID:FIBG_HUMAN; ENSEMBL ID: ENSG00000171557; HGNC ID: 3694
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
78N-linked (GlcNAc...).
334N-linked (GlcNAc...); in variant Asahi.
444Sulfotyrosine.
448Sulfotyrosine.
Location(AA) Modifications Resource
78N-linked (GlcNAc...).Swiss-Prot 53.0
334N-linked (GlcNAc...); in variant Asahi.Swiss-Prot 53.0
424Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-432).Swiss-Prot 53.0
432Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-424).Swiss-Prot 53.0
444Sulfotyrosine.Swiss-Prot 53.0
448Sulfotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
43Phosphoserine(IKK)HMM predict
43Phosphoserine(PKB)HMM predict
78N-linkedHMM predict
100Phosphoserine(CK1)HMM predict
100Phosphoserine(IKK)HMM predict
245Phosphoserine(CDC2)HMM predict
380Phosphotyrosine(INSR)HMM predict
385Phosphothreonine(CDC2)HMM predict
389Phosphotyrosine(INSR)HMM predict
439ProlineHMM predict
444Phosphotyrosine(EGFR)HMM predict
444Phosphotyrosine(INSR)HMM predict
444Phosphotyrosine(SRC)HMM predict
444Phosphotyrosine(Syk)HMM predict
444SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021870
  • Location:chr4 155745178-155753351
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 155759424 155759600 176 6161
CTCF CD4SISSRdata 155759424 155759600 176 6161
CTCF G2GSE9613 155759164 155759671 507 6066
CTCF G2GSE9613 155766910 155767705 795 13956
FoxA1 MCF7MACSdata 155758424 155758713 289 5217
USF1 HepG2E 155753055 155753742 687 47
USF2 HepG2E 155758531 155758981 450 5405
hScc1 BcellGSE12603 155759164 155759671 507 6066
hScc1 BcellGSE12603 155763388 155763678 290 10182
hScc1 CdLSGSE12603 155759241 155759804 563 6171
hScc1 CdLSGSE12603 155763388 155763713 325 10199
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 155753055 155753640 585 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018