AutismKB 2.0

Annotation Detail for IKZF2


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Basic Information Top
Gene Symbol:IKZF2 ( HELIOS,MGC34330,ZNF1A2,ZNFN1A2 )
Gene Full Name: IKAROS family zinc finger 2 (Helios)
Band: 2q34
Quick LinksEntrez ID:22807; OMIM: 606234; Uniprot ID:IKZF2_HUMAN; ENSEMBL ID: ENSG00000030419; HGNC ID: 13177
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
56Phosphoserine.
78Phosphoserine.
79Phosphoserine.
174Phosphoserine.
175Phosphotyrosine.
288N6-acetyllysine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016260
  • Location:chr2 213579588-213723302
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 213724468 213725120 652 1492
H3K4me3 colorectalcancer 213723921 213724505 584 911
H3K4me3 colorectalcancer 213725455 213725759 304 2305
NRSF mAbJurkat 213723848 213724284 436 764
PHF8 HeLaGSE20725 213724449 213725611 1162 1728
TFAP2C MCF7GSE21234 213724819 213725569 750 1892
hScc1 BcellGSE12603 213724431 213725522 1091 1674
hScc1 BcellGSE12603 213726612 213727137 525 3572
hScc1 CdLSGSE12603 213726323 213727137 814 3428
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 213722361 213722686 325 0
Rb shRbSenescenceGSE19898 213595220 213595467 247 0
hScc1 BcellGSE12603 213722108 213722361 253 0
p63 keratinocytesGSE17611 213671493 213672174 681 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018