AutismKB 2.0

Annotation Detail for LPHN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LPHN1 ( CIRL1,CL1,LEC2 )
Gene Full Name: latrophilin 1
Band: 19p13.2
Quick LinksEntrez ID:22859; OMIM: NA; Uniprot ID:LPHN1_HUMAN; ENSEMBL ID: ENSG00000072071; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
98N-linked (GlcNAc...) (Potential).
531N-linked (GlcNAc...) (Potential).
640N-linked (GlcNAc...) (Potential).
742N-linked (GlcNAc...) (Potential).
801N-linked (GlcNAc...) (Potential).
806N-linked (GlcNAc...) (Potential).
827N-linked (GlcNAc...) (Potential).
1377Phosphoserine (By similarity).
1440Phosphotyrosine.
Location(AA) Modifications Resource
98N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
531N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
640N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
742N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
801N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
806N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
827N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1377Phosphoserine (By similarity).Swiss-Prot 53.0
1440Phosphotyrosine.Swiss-Prot 53.0
1440PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
19O-linkedHMM predict
20O-linkedHMM predict
20O-linkedHMM predict
98N-linkedHMM predict
316Phosphoserine(PKB)HMM predict
374Phosphotyrosine(Syk)HMM predict
402O-linkedHMM predict
407O-linkedHMM predict
408Phosphoserine(MAPK)HMM predict
408O-linkedHMM predict
412O-linkedHMM predict
412O-linkedHMM predict
413O-linkedHMM predict
414O-linkedHMM predict
416O-linkedHMM predict
420O-linkedHMM predict
420Phosphothreonine(MAPK)HMM predict
420Phosphothreonine(CDK)HMM predict
423O-linkedHMM predict
424O-linkedHMM predict
424O-linkedHMM predict
427Phosphoserine(CAMK2)HMM predict
427O-linkedHMM predict
427Phosphoserine(IKK)HMM predict
427Phosphoserine(CDC2)HMM predict
432Phosphothreonine(CDK)HMM predict
432Phosphothreonine(CDC2)HMM predict
432Phosphothreonine(MAPK)HMM predict
463O-linkedHMM predict
463O-linkedHMM predict
531N-linkedHMM predict
640N-linkedHMM predict
707Phosphoserine(PKG)HMM predict
707Phosphoserine(PKA)HMM predict
801N-linkedHMM predict
806N-linkedHMM predict
818Phosphothreonine(PKC)HMM predict
827N-linkedHMM predict
878S-palmitoylHMM predict
961Phosphoserine(CK1)HMM predict
1142SulfotyrosineHMM predict
1154N-linkedHMM predict
1171N-linkedHMM predict
1177N-linkedHMM predict
1198Phosphoserine(CDC2)HMM predict
1211N-linkedHMM predict
1214Phosphoserine(MAPK)HMM predict
1214Phosphoserine(ATM)HMM predict
1220Phosphoserine(CDC2)HMM predict
1270MethylarginineHMM predict
1298O-linkedHMM predict
1351Phosphoserine(PKG)HMM predict
1372O-linkedHMM predict
1376PhosphoserineHMM predict
1377Phosphoserine(CDC2)HMM predict
1394Phosphoserine(CDC2)HMM predict
1401Phosphoserine(CDC2)HMM predict
1401O-linkedHMM predict
1406O-linkedHMM predict
1447Phosphoserine(PKA)HMM predict
1451Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001008701
  • Location:chr19 14119550-14177996
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 14189287 14189439 152 11367
CTCF CD4GSE12889 14193363 14193512 149 15441
CTCF CD4SISSRdata 14189287 14189439 152 11367
CTCF CD4SISSRdata 14193363 14193512 149 15441
CTCF JurkatGSE12889 14193338 14193524 186 15435
CTCF G2GSE9613 14189052 14189734 682 11397
Oct4 hESGSE17917 14193043 14193231 188 15141
USF2 HepG2E 14178905 14180005 1100 1459
hScc1 BcellGSE12603 14178573 14178865 292 723
hScc1 BcellGSE12603 14189052 14189595 543 11327
hScc1 CdLSGSE12603 14189052 14189734 682 11397
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 14118531 14119034 503 768
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 14167880 14168110 230 0
CTCF CD4SISSRdata 14167880 14168110 230 0
CTCF HelaGSE12889 14119980 14120162 182 0
CTCF JurkatGSE12889 14172113 14172275 162 0
CTCF G2GSE9613 14119773 14120318 545 0
CTCF G2GSE9613 14135024 14135435 411 0
CTCF G2GSE9613 14167365 14168123 758 0
CTCF G2GSE9613 14169816 14170519 703 0
CTCF G2GSE9613 14171859 14172201 342 0
KLF4 hESGSE17917 14159388 14159549 161 0
Oct1 HelaGSE14283 14149155 14149187 32 0
TFAP2C MCF7GSE21234 14132678 14133069 391 0
hScc1 BcellGSE12603 14119943 14120439 496 0
hScc1 BcellGSE12603 14167486 14168123 637 0
hScc1 BcellGSE12603 14171859 14172201 342 0
hScc1 BcellGSE12603 14177207 14177948 741 0
hScc1 CdLSGSE12603 14167642 14168123 481 0
hScc1 CdLSGSE12603 14171927 14172201 274 0
hScc1 G2GSE9613 14167329 14168123 794 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
12792 EST chr19 14108999 14127605 169 mRNA LPHN1 chr19 14119549 14177997Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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