AutismKB 2.0

Annotation Detail for FKBP5


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Basic Information Top
Gene Symbol:FKBP5 ( AIG6,FKBP51,FKBP54,MGC111006,P54,PPIase,Ptg-10 )
Gene Full Name: FK506 binding protein 5
Band: 6p21.31
Quick LinksEntrez ID:2289; OMIM: 602623; Uniprot ID:FKBP5_HUMAN; ENSEMBL ID: ENSG00000096060; HGNC ID: 3721
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
13Phosphoserine.
445Phosphoserine.
Location(AA) Modifications Resource
13Phosphoserine.Swiss-Prot 53.0
13PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
54Phosphotyrosine(Jak)HMM predict
62Phosphoserine(PKG)HMM predict
113Phosphotyrosine(SRC)HMM predict
125N-linkedHMM predict
159Phosphotyrosine(INSR)HMM predict
160Phosphoserine(INSR)HMM predict
284Phosphotyrosine(INSR)HMM predict
409Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004117
  • Location:chr6 35649345-35764691
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 35779990 35780133 143 15370
ER E2-MCF7GSE14664 35772332 35772423 91 7686
ER Fulvestrant-MCF7GSE14664 35772332 35772418 86 7684
Fos K562GSE19551 35764562 35765179 617 179
Fos K562GSE19551 35770187 35770704 517 5754
H3ac HepG2E 35765000 35765279 279 448
H3ac HepG2E 35766857 35767794 937 2634
Jun K562GSE19551 35770133 35770666 533 5708
Myc K562GSE19551 35770286 35770538 252 5721
PHF8 293TGSE20725 35764258 35765154 896 15
USF1 HepG2E 35764964 35765279 315 430
USF2 HepG2E 35764964 35765279 315 430
USF2 HepG2E 35767221 35767576 355 2707
p130 SenescentGSE19898 35764703 35765126 423 223
p130 shRbSenescentGSE19898 35764698 35764879 181 97
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35644718 35645099 381 4437
CTCF CD4SISSRdata 35644718 35645099 381 4437
CTCF HelaGSE12889 35644763 35645038 275 4445
CTCF G2GSE9613 35644577 35645064 487 4525
hScc1 BcellGSE12603 35631597 35631778 181 17658
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35700263 35700452 189 0
CTCF CD4SISSRdata 35700263 35700452 189 0
CTCF G2GSE9613 35659538 35660049 511 0
CTCF G2GSE9613 35763773 35765279 1506 0
ER MCF7E 35748066 35748372 306 0
H3K4me2 HCT116GSE10453 35763250 35763704 454 0
H3K4me3 colorectalcancer 35763250 35763876 626 0
H3ac HepG2E 35763014 35763809 795 0
NFkBII GM15510GSE19485 35763307 35765308 2001 0
Nanog ESGSE20650 35677072 35677461 389 0
Oct1 HelaGSE14283 35680965 35680994 29 0
Oct1 HelaGSE14283 35711649 35711713 64 0
STAT1 HeLaGSE12782 35676706 35678929 2223 0
STAT1 HeLaGSE12783 35676740 35679064 2324 0
TAF HelaGSE8489 35762812 35763773 961 0
TAF k562GSE8489 35743061 35743300 239 0
TAF k562GSE8489 35761778 35763843 2065 0
TFAP2C MCF7GSE21234 35677651 35677961 310 0
hScc1 BcellGSE12603 35659538 35660086 548 0
hScc1 BcellGSE12603 35763633 35765000 1367 0
hScc1 CdLSGSE12603 35659538 35660200 662 0
hScc1 CdLSGSE12603 35763345 35764115 770 0
hScc1 G2GSE9613 35659282 35660379 1097 0
hScc1 G2GSE9613 35763737 35764822 1085 0
p130 QuiescentGSE19898 35659720 35659891 171 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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