AutismKB 2.0

Annotation Detail for DIS3


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Basic Information Top
Gene Symbol:DIS3 ( DKFZp667L1817,EXOSC11,FLJ10484,KIAA1008,MGC33035,RP11-342J4.3,RRP44,bA555G22.1,dis3p )
Gene Full Name: DIS3 mitotic control homolog (S. cerevisiae)
Band: 13q21.33
Quick LinksEntrez ID:22894; OMIM: 607533; Uniprot ID:RRP44_HUMAN; ENSEMBL ID: ENSG00000083520; HGNC ID: 20604
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
18N6-acetyllysine.
922N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
57O-linkedHMM predict
58O-linkedHMM predict
100N-linkedHMM predict
254Phosphoserine(PKG)HMM predict
258Phosphotyrosine(Syk)HMM predict
391Phosphoserine(PKG)HMM predict
445Phosphoserine(ATM)HMM predict
528Phosphothreonine(PKA)HMM predict
529Phosphothreonine(PKA)HMM predict
531Phosphotyrosine(Jak)HMM predict
634Phosphoserine(CDC2)HMM predict
683Phosphoserine(CK1)HMM predict
730Phosphoserine(CDC2)HMM predict
887SulfotyrosineHMM predict
936O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014953
  • Location:chr13 72227541-72254006
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 72253704 72254435 731 63
PHF8 HeLaGSE20725 72253315 72254821 1506 62
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 72252509 72252880 371 0
H3K4me3 colorectalcancer 72253159 72254102 943 0
H3ac HepG2E 72252630 72253740 1110 0
hScc1 BcellGSE12603 72253740 72253951 211 0
p63 keratinocytesGSE17611 72246040 72246612 572 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
7314 mRNA FLJ22624 chr13 72200042 72228329 788 mRNA KIAA1008 chr13 72227541 72254007Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018