AutismKB 2.0

Annotation Detail for DKK1


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Basic Information Top
Gene Symbol:DKK1 ( DKK-1,SK )
Gene Full Name: dickkopf homolog 1 (Xenopus laevis)
Band: 10q21.1
Quick LinksEntrez ID:22943; OMIM: 605189; Uniprot ID:DKK1_HUMAN; ENSEMBL ID: ENSG00000107984; HGNC ID: 2891
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
256N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
256N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
58O-linkedHMM predict
58O-linkedHMM predict
74Phosphotyrosine(INSR)HMM predict
76Phosphothreonine(PKC)HMM predict
99Phosphoserine(CDC2)HMM predict
111S-palmitoylHMM predict
114S-palmitoylHMM predict
173Phosphothreonine(PKA)HMM predict
173Phosphothreonine(PKC)HMM predict
256N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012242
  • Location:chr10 53744046-53747421
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 53737968 53739634 1666 5246
H3ac HepG2E 53740860 53741625 765 2804
H3ac HepG2E 53742235 53743569 1334 1145
USF2 HepG2E 53737936 53738619 683 5769
USF2 HepG2E 53742881 53743569 688 822
hScc1 BcellGSE12603 53737856 53738375 519 5931
hScc1 CdLSGSE12603 53737694 53738969 1275 5715
hScc1 G2GSE9613 53737659 53738375 716 6030
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 53753010 53753051 41 5609
Oct1 HelaGSE14283 53750654 53750691 37 3251
Oct1 HelaGSE14283 53753005 53753051 46 5607
P300 T30-glioblastomaGSE21026 53748341 53749450 1109 1474
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 53746004 53746538 534 0
H3ac HepG2E 53743932 53748267 4335 0
Rb SenescentGSE19898 53744198 53744682 484 0
hScc1 CdLSGSE12603 53744193 53744638 445 0
hScc1 G2GSE9613 53744043 53744830 787 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-31 hsa-mir-31 9 21048943
hsa-miR-31* hsa-mir-31 9 21048943
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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