AutismKB 2.0

Annotation Detail for NT5C2


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Basic Information Top
Gene Symbol:NT5C2 ( GMP,NT5B,PNT5,cN-II )
Gene Full Name: 5'-nucleotidase, cytosolic II
Band: 10q24.32-q24.33
Quick LinksEntrez ID:22978; OMIM: 600417; Uniprot ID:5NTC_HUMAN; ENSEMBL ID: ENSG00000076685; HGNC ID: 8022
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
502Phosphoserine.
527Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
65Phosphotyrosine(INSR)HMM predict
65Phosphotyrosine(SRC)HMM predict
275O-linkedHMM predict
387Phosphoserine(CK2)HMM predict
410Phosphoserine(CK1)HMM predict
427Phosphothreonine(PKA)HMM predict
443Phosphoserine(CDK)HMM predict
508N-linkedHMM predict
529Phosphoserine(CAMK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012229
  • Location:chr10 104837903-104943005
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 104946825 104947502 677 4158
Nanog ESGSE20650 104954563 104955198 635 11875
Nanog hESGSE18292 104954562 104955143 581 11847
USF2 HepG2E 104954425 104955162 737 11788
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 104925549 104925604 55 0
ER MCF7GSE19013 104872158 104872749 591 0
ER MCF7GSE19013 104875430 104876243 813 0
ER MCF7GSE19013 104910185 104910749 564 0
ER MCF7GSE19013 104917970 104918936 966 0
Fos K562GSE19551 104875648 104876016 368 0
Fos K562GSE19551 104895975 104896227 252 0
FoxA1 MCF7MACSdata 104880767 104880951 184 0
H3K4me2 HCT116GSE10453 104941400 104942270 870 0
H3ac HepG2E 104941145 104942130 985 0
NFkBII GM12892GSE19485 104884682 104885655 973 0
Oct1 H2O2-HelaGSE14283 104894057 104894087 30 0
Oct1 H2O2-HelaGSE14283 104928109 104928152 43 0
Oct1 HelaGSE14283 104925539 104925594 55 0
Oct1 HelaGSE14283 104928117 104928150 33 0
PAX3-FKHR Rh4GSE19063 104889887 104890943 1056 0
hScc1 CdLSGSE12603 104875874 104876060 186 0
hScc1 CdLSGSE12603 104941781 104942270 489 0
p63 keratinocytesGSE17611 104864522 104865288 766 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018