AutismKB 2.0

Annotation Detail for WDFY3


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Basic Information Top
Gene Symbol:WDFY3 ( ALFY,KIAA0993,MGC16461,ZFYVE25 )
Gene Full Name: WD repeat and FYVE domain containing 3
Band: 4q21.23
Quick LinksEntrez ID:23001; OMIM: NA; Uniprot ID:WDFY3_HUMAN; ENSEMBL ID: ENSG00000163625,ENSG00000250675,ENSG00000251089; HGNC ID: 20751
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
653Phosphotyrosine.
813Phosphotyrosine.
815Phosphoserine.
817Phosphoserine.
818Phosphothreonine.
822Phosphotyrosine.
1696Phosphoserine.
1699Phosphoserine.
3335Phosphoserine (By similarity).
Location(AA) Modifications Resource
1011PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
17Phosphoserine(ATM)HMM predict
36S-palmitoylHMM predict
97Phosphoserine(PKC)HMM predict
97Phosphoserine(PKG)HMM predict
97Phosphoserine(IKK)HMM predict
97Phosphoserine(PKB)HMM predict
115N-linkedHMM predict
148Phosphoserine(IKK)HMM predict
221O-linkedHMM predict
222Phosphoserine(IKK)HMM predict
275Phosphoserine(ATM)HMM predict
297Phosphoserine(IKK)HMM predict
428Phosphoserine(ATM)HMM predict
535N-linkedHMM predict
536N-linkedHMM predict
599Phosphoserine(MAPK)HMM predict
643Phosphothreonine(PKC)HMM predict
732Phosphoserine(PKG)HMM predict
754Phosphoserine(CK1)HMM predict
761Phosphothreonine(PKC)HMM predict
796Phosphoserine(CK1)HMM predict
796Phosphoserine(IKK)HMM predict
799O-linkedHMM predict
799Phosphoserine(CDC2)HMM predict
813Phosphotyrosine(INSR)HMM predict
817O-linkedHMM predict
995Phosphoserine(CK1)HMM predict
1071N-linkedHMM predict
1072N-linkedHMM predict
1124Phosphothreonine(PKC)HMM predict
1130N-linkedHMM predict
1131Phosphoserine(PKG)HMM predict
1131Phosphoserine(CK1)HMM predict
1167Phosphoserine(CK1)HMM predict
1171Phosphoserine(CK1)HMM predict
1179S-palmitoylHMM predict
1207N-linkedHMM predict
1236O-linkedHMM predict
1243O-linkedHMM predict
1279N-linkedHMM predict
1312O-linkedHMM predict
1312Phosphoserine(CDC2)HMM predict
1333O-linkedHMM predict
1335Phosphothreonine(PKC)HMM predict
1362N-linkedHMM predict
1377N-linkedHMM predict
1466Phosphoserine(PKA)HMM predict
1494N-linkedHMM predict
1531Phosphoserine(CK2)HMM predict
1557Phosphoserine(CK1)HMM predict
1557Phosphoserine(IKK)HMM predict
1559Phosphoserine(ATM)HMM predict
1719Phosphoserine(IKK)HMM predict
1742Phosphothreonine(PKC)HMM predict
1825O-linkedHMM predict
1827Phosphothreonine(PKC)HMM predict
1923Phosphoserine(CK2)HMM predict
1923Phosphoserine(CDC2)HMM predict
1938N-linkedHMM predict
1940Phosphoserine(PKG)HMM predict
1940Phosphoserine(ATM)HMM predict
1944Phosphotyrosine(Syk)HMM predict
2096N-linkedHMM predict
2147S-palmitoylHMM predict
2169Phosphothreonine(PKC)HMM predict
2186Phosphoserine(ATM)HMM predict
2210Phosphoserine(CK1)HMM predict
2295Phosphoserine(PKG)HMM predict
2326Phosphotyrosine(Syk)HMM predict
2329Phosphotyrosine(Syk)HMM predict
2394SulfotyrosineHMM predict
2434Phosphoserine(PKG)HMM predict
2434Phosphoserine(CAMK2)HMM predict
2434Phosphoserine(PKB)HMM predict
2440Phosphotyrosine(Jak)HMM predict
2440Phosphotyrosine(Syk)HMM predict
2441Phosphotyrosine(INSR)HMM predict
2441Phosphotyrosine(Syk)HMM predict
2492Phosphoserine(PKA)HMM predict
2492Phosphoserine(PKB)HMM predict
2513Phosphoserine(CK2)HMM predict
2514Phosphoserine(CK2)HMM predict
2523N-linkedHMM predict
2665Phosphoserine(CK1)HMM predict
2668Phosphoserine(CK1)HMM predict
2668Phosphoserine(CK2)HMM predict
2695Phosphothreonine(PKC)HMM predict
2738PhosphoserineHMM predict
2870N-linkedHMM predict
3013Phosphothreonine(MAPK)HMM predict
3013PhosphothreonineHMM predict
3047N-linkedHMM predict
3099O-linkedHMM predict
3254O-linkedHMM predict
3254Phosphothreonine(CDC2)HMM predict
3254Phosphothreonine(MAPK)HMM predict
3283Phosphoserine(CK1)HMM predict
3284Phosphoserine(CK1)HMM predict
3284Phosphoserine(CK2)HMM predict
3292Phosphoserine(CK1)HMM predict
3292Phosphoserine(IKK)HMM predict
3294Phosphoserine(ATM)HMM predict
3300Phosphothreonine(MAPK)HMM predict
3300Phosphothreonine(CDK)HMM predict
3302O-linkedHMM predict
3302Phosphoserine(CK1)HMM predict
3302Phosphoserine(ATM)HMM predict
3302Phosphoserine(IKK)HMM predict
3305Phosphoserine(CK1)HMM predict
3315Phosphoserine(IKK)HMM predict
3315Phosphoserine(PKB)HMM predict
3350N-linkedHMM predict
3356Phosphothreonine(PKC)HMM predict
3365Phosphoserine(ATM)HMM predict
3376N-linkedHMM predict
3459Phosphoserine(IKK)HMM predict
3484S-palmitoylHMM predict
3501Phosphoserine(CDC2)HMM predict
3510TyrosineHMM predict
3512AsparagineHMM predict
3519Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014991
  • Location:chr4 85809718-86106567
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 86111617 86111785 168 5134
CTCF CD4SISSRdata 86111617 86111785 168 5134
CTCF G2GSE9613 86105756 86107402 1646 12
Fos K562GSE19551 86126128 86126653 525 19823
Oct1 HelaGSE14283 86126100 86126165 65 19565
PHF8 293TGSE20725 86106224 86107309 1085 199
Rb SenescentGSE19898 86106831 86107137 306 417
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 85831287 85832253 966 0
ER Fulvestrant-MCF7GSE14664 86075063 86075096 33 0
H3K4me3 colorectalcancer 86105385 86105756 371 0
Oct1 H2O2-HelaGSE14283 85923017 85923067 50 0
Oct1 HelaGSE14283 85826462 85826494 32 0
Oct1 HelaGSE14283 85923017 85923053 36 0
Oct1 HelaGSE14283 85923527 85923555 28 0
Oct1 HelaGSE14283 85929122 85929192 70 0
Oct1 HelaGSE14283 85940223 85940258 35 0
Oct1 HelaGSE14283 86058001 86058028 27 0
Oct1 HelaGSE14283 86075070 86075097 27 0
Oct1 HelaGSE14283 86091928 86091960 32 0
P300 T30-glioblastomaGSE21026 85830494 85832291 1797 0
PHF8 HeLaGSE20725 86105586 86107366 1780 0
hScc1 BcellGSE12603 86105864 86106793 929 0
hScc1 G2GSE9613 86105685 86106924 1239 0
p63 keratinocytesGSE17611 85940380 85941198 818 0
p63 keratinocytesGSE17611 86091838 86092786 948 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19928 EST chr4 86081592 86088723 414 mRNA WDFY3 chr4 85947873 86244723Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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