AutismKB 2.0

Annotation Detail for NCOA6


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Basic Information Top
Gene Symbol:NCOA6 ( AIB3,ASC2,KIAA0181,NRC,PRIP,RAP250,TRBP )
Gene Full Name: nuclear receptor coactivator 6
Band: 20q11.22
Quick LinksEntrez ID:23054; OMIM: 605299; Uniprot ID:NCOA6_HUMAN; ENSEMBL ID: ENSG00000198646; HGNC ID: 15936
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
884Phosphoserine; by MAPK; in vitro.
891LXXLL motif 1.
1321Phosphothreonine.
1495LXXLL motif 2.
Location(AA) Modifications Resource
884Phosphoserine; by MAPK; in vitro.Swiss-Prot 53.0
1321Phosphothreonine.Swiss-Prot 53.0
1321PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
18O-linkedHMM predict
41Phosphoserine(CK2)HMM predict
191O-linkedHMM predict
192O-linkedHMM predict
207Phosphothreonine(CDC2)HMM predict
207Phosphothreonine(MAPK)HMM predict
212Phosphoserine(IKK)HMM predict
233O-linkedHMM predict
235O-linkedHMM predict
310O-linkedHMM predict
334O-linkedHMM predict
334Phosphoserine(IKK)HMM predict
368Phosphothreonine(MAPK)HMM predict
368Phosphothreonine(CDK)HMM predict
370O-linkedHMM predict
384Phosphoserine(ATM)HMM predict
384Phosphoserine(IKK)HMM predict
412O-linkedHMM predict
416Phosphothreonine(CDK)HMM predict
425N-linkedHMM predict
427Phosphoserine(CDC2)HMM predict
430O-linkedHMM predict
430Phosphoserine(IKK)HMM predict
431O-linkedHMM predict
431Phosphoserine(ATM)HMM predict
439O-linkedHMM predict
439Phosphoserine(CDC2)HMM predict
439Phosphoserine(IKK)HMM predict
442O-linkedHMM predict
443O-linkedHMM predict
443Phosphoserine(CDC2)HMM predict
443Phosphoserine(CDK)HMM predict
445O-linkedHMM predict
447N-linkedHMM predict
473Phosphoserine(CDC2)HMM predict
535O-linkedHMM predict
535O-linkedHMM predict
536O-linkedHMM predict
536O-linkedHMM predict
537O-linkedHMM predict
539O-linkedHMM predict
540O-linkedHMM predict
540Phosphothreonine(MAPK)HMM predict
544O-linkedHMM predict
619Phosphoserine(ATM)HMM predict
631Phosphoserine(ATM)HMM predict
673Phosphoserine(CDC2)HMM predict
678Phosphothreonine(PKA)HMM predict
678Phosphothreonine(CDC2)HMM predict
678Phosphothreonine(CDK)HMM predict
678PhosphothreonineHMM predict
685Phosphoserine(ATM)HMM predict
774N-linkedHMM predict
775N-linkedHMM predict
776Phosphoserine(CDC2)HMM predict
807O-linkedHMM predict
884Phosphoserine(MAPK)HMM predict
907N-linkedHMM predict
908N-linkedHMM predict
910N-linkedHMM predict
912N-linkedHMM predict
926Phosphoserine(PKA)HMM predict
975Phosphoserine(ATM)HMM predict
1019O-linkedHMM predict
1019Phosphoserine(ATM)HMM predict
1023Phosphoserine(IKK)HMM predict
1051Phosphoserine(ATM)HMM predict
1075Phosphoserine(ATM)HMM predict
1087Phosphoserine(ATM)HMM predict
1091Phosphoserine(CDC2)HMM predict
1091Phosphoserine(CDK)HMM predict
1091Phosphoserine(IKK)HMM predict
1120N-linkedHMM predict
1122O-linkedHMM predict
1124Phosphoserine(CDC2)HMM predict
1124Phosphoserine(MAPK)HMM predict
1138O-linkedHMM predict
1138Phosphoserine(IKK)HMM predict
1142Phosphoserine(CK1)HMM predict
1171O-linkedHMM predict
1171Phosphoserine(CDC2)HMM predict
1174O-linkedHMM predict
1176O-linkedHMM predict
1191Phosphoserine(CK1)HMM predict
1206O-linkedHMM predict
1206O-linkedHMM predict
1206Phosphothreonine(PKC)HMM predict
1211Phosphothreonine(CDC2)HMM predict
1211Phosphothreonine(MAPK)HMM predict
1211Phosphothreonine(CDK)HMM predict
1220Phosphotyrosine(Syk)HMM predict
1221SulfotyrosineHMM predict
1224Phosphothreonine(MAPK)HMM predict
1231O-linkedHMM predict
1235O-linkedHMM predict
1240Phosphoserine(CDC2)HMM predict
1276N-linkedHMM predict
1288Phosphoserine(IKK)HMM predict
1289N-linkedHMM predict
1293N-linkedHMM predict
1296N-linkedHMM predict
1316Phosphoserine(PKG)HMM predict
1321Phosphothreonine(PKC)HMM predict
1325Phosphoserine(CAMK2)HMM predict
1325Phosphoserine(CDC2)HMM predict
1325Phosphoserine(CDK)HMM predict
1332Phosphoserine(CK1)HMM predict
1333Phosphoserine(CAMK2)HMM predict
1333Phosphoserine(CDC2)HMM predict
1333Phosphoserine(IKK)HMM predict
1333Phosphoserine(PKB)HMM predict
1336Phosphoserine(CDC2)HMM predict
1336Phosphoserine(CDK)HMM predict
1339MethyllysineHMM predict
1340Phosphothreonine(PKC)HMM predict
1341O-linkedHMM predict
1343O-linkedHMM predict
1343Phosphoserine(CDC2)HMM predict
1343PhosphoserineHMM predict
1349Phosphoserine(PKG)HMM predict
1377Phosphoserine(CDC2)HMM predict
1389Phosphoserine(IKK)HMM predict
1392N-linkedHMM predict
1393N-linkedHMM predict
1397N-linkedHMM predict
1400N-linkedHMM predict
1404O-linkedHMM predict
1490Phosphoserine(IKK)HMM predict
1502N-linkedHMM predict
1504O-linkedHMM predict
1516Phosphothreonine(MAPK)HMM predict
1539Phosphoserine(CK1)HMM predict
1558Phosphoserine(CK1)HMM predict
1565Phosphoserine(CK1)HMM predict
1574O-linkedHMM predict
1584Phosphoserine(CK2)HMM predict
1585O-linkedHMM predict
1585O-linkedHMM predict
1587Phosphoserine(CK1)HMM predict
1590O-linkedHMM predict
1590O-linkedHMM predict
1590Phosphothreonine(CDK)HMM predict
1603O-linkedHMM predict
1607O-linkedHMM predict
1608O-linkedHMM predict
1612O-linkedHMM predict
1612O-linkedHMM predict
1613O-linkedHMM predict
1613O-linkedHMM predict
1645Phosphoserine(IKK)HMM predict
1649Phosphoserine(IKK)HMM predict
1662N-linkedHMM predict
1676O-linkedHMM predict
1677O-linkedHMM predict
1687O-linkedHMM predict
1693O-linkedHMM predict
1709O-linkedHMM predict
1719Phosphoserine(CK2)HMM predict
1720O-linkedHMM predict
1721Phosphoserine(CDC2)HMM predict
1721Phosphoserine(CDK)HMM predict
1721Phosphoserine(ATM)HMM predict
1735O-linkedHMM predict
1745O-linkedHMM predict
1749O-linkedHMM predict
1749O-linkedHMM predict
1750O-linkedHMM predict
1751Phosphoserine(CDC2)HMM predict
1756O-linkedHMM predict
1776N-linkedHMM predict
1777O-linkedHMM predict
1782N-linkedHMM predict
1787Phosphoserine(ATM)HMM predict
1787Phosphoserine(IKK)HMM predict
1789O-linkedHMM predict
1789Phosphoserine(PKA)HMM predict
1790O-linkedHMM predict
1791O-linkedHMM predict
1800Phosphoserine(CDC2)HMM predict
1800Phosphoserine(MAPK)HMM predict
1800Phosphoserine(CDK)HMM predict
1809Phosphoserine(CDC2)HMM predict
1812O-linkedHMM predict
1836Phosphothreonine(PKA)HMM predict
1876O-linkedHMM predict
1880O-linkedHMM predict
1892Phosphoserine(CDC2)HMM predict
1900O-linkedHMM predict
1912Phosphothreonine(PKC)HMM predict
2018Phosphoserine(PKG)HMM predict
2038Phosphoserine(PKG)HMM predict
2039Phosphoserine(PKA)HMM predict
2043O-linkedHMM predict
2043Phosphoserine(IKK)HMM predict
2046Phosphoserine(CK1)HMM predict
2047Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014071
  • Location:chr20 32766239-32877093
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 32885888 32886143 255 8922
CTCF CD4SISSRdata 32885888 32886143 255 8922
USF1 HepG2E 32877230 32877754 524 399
USF2 HepG2E 32877230 32877754 524 399
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 32821262 32821487 225 0
CTCF CD4SISSRdata 32821262 32821487 225 0
CTCF G2GSE9613 32876367 32876719 352 0
H3K4me3 colorectalcancer 32876104 32876620 516 0
H3ac HepG2E 32873363 32874056 693 0
H3ac HepG2E 32875660 32876719 1059 0
PHF8 HeLaGSE20725 32875896 32877838 1942 0
TAF HelaGSE8489 32875699 32876656 957 0
USF1 HepG2E 32875856 32876719 863 0
hScc1 BcellGSE12603 32767704 32767884 180 0
hScc1 BcellGSE12603 32821298 32821482 184 0
hScc1 BcellGSE12603 32876292 32876719 427 0
p130 QuiescentGSE19898 32802020 32802179 159 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-196a hsa-mir-196a-1 17 15105502
hsa-miR-196a hsa-mir-196a-2 12 15105502
hsa-miR-196a hsa-mir-196a-1 17 15105502
hsa-miR-196a hsa-mir-196a-2 12 15105502
hsa-miR-196a* hsa-mir-196a-2 12 15105502
hsa-miR-196a* hsa-mir-196a-2 12 15105502
hsa-miR-196b hsa-mir-196b 7 15105502
hsa-miR-196b hsa-mir-196b 7 15105502
hsa-miR-205 hsa-mir-205 1 20065103
hsa-miR-205 hsa-mir-205 1 20065103
hsa-miR-224 hsa-mir-224 X 20065103
hsa-miR-224 hsa-mir-224 X 20065103
hsa-miR-335 hsa-mir-335 7 20065103
hsa-miR-335 hsa-mir-335 7 20065103
hsa-miR-335* hsa-mir-335 7 20065103
hsa-miR-335* hsa-mir-335 7 20065103
hsa-miR-424 hsa-mir-424 X 20065103
hsa-miR-424 hsa-mir-424 X 20065103
hsa-miR-424* hsa-mir-424 X 20065103
hsa-miR-424* hsa-mir-424 X 20065103
hsa-miR-451 hsa-mir-451 17 20065103
hsa-miR-451 hsa-mir-451 17 20065103
hsa-miR-491-3p hsa-mir-491 9 20065103
hsa-miR-491-3p hsa-mir-491 9 20065103
hsa-miR-491-5p hsa-mir-491 9 20065103
hsa-miR-491-5p hsa-mir-491 9 20065103
hsa-miR-93 hsa-mir-93 7 20065103
hsa-miR-93 hsa-mir-93 7 20065103
hsa-miR-93* hsa-mir-93 7 20065103
hsa-miR-93* hsa-mir-93 7 20065103
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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