AutismKB 2.0

Annotation Detail for SIPA1L3


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Basic Information Top
Gene Symbol:SIPA1L3 ( SPAL3 )
Gene Full Name: signal-induced proliferation-associated 1 like 3
Band: 19q13.13-q13.2
Quick LinksEntrez ID:23094; OMIM: NA; Uniprot ID:SI1L3_HUMAN; ENSEMBL ID: ENSG00000105738; HGNC ID: 23801
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1135Phosphoserine.
1265Phosphotyrosine.
1364Phosphoserine.
1448N6-acetyllysine.
1544Phosphoserine.
1699Phosphothreonine.
Location(AA) Modifications Resource
1265Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
43N-linkedHMM predict
45Phosphoserine(IKK)HMM predict
53Phosphoserine(CDC2)HMM predict
56O-linkedHMM predict
56O-linkedHMM predict
58O-linkedHMM predict
60O-linkedHMM predict
62O-linkedHMM predict
64O-linkedHMM predict
68O-linkedHMM predict
68Phosphoserine(CDC2)HMM predict
70O-linkedHMM predict
97Phosphoserine(IKK)HMM predict
98N-linkedHMM predict
100PhosphoserineHMM predict
102O-linkedHMM predict
102Phosphoserine(ATM)HMM predict
127O-linkedHMM predict
128O-linkedHMM predict
128O-linkedHMM predict
129O-linkedHMM predict
129Phosphothreonine(MAPK)HMM predict
133O-linkedHMM predict
133Phosphoserine(CDK)HMM predict
146Phosphoserine(PKA)HMM predict
146Phosphoserine(PKG)HMM predict
146Phosphoserine(PKB)HMM predict
158Phosphoserine(CDC2)HMM predict
172Phosphoserine(CK1)HMM predict
308Phosphoserine(CK1)HMM predict
367N-linkedHMM predict
368Phosphothreonine(PKA)HMM predict
373O-linkedHMM predict
376O-linkedHMM predict
383O-linkedHMM predict
391Phosphoserine(CAMK2)HMM predict
445O-linkedHMM predict
451Phosphoserine(CDC2)HMM predict
487Phosphoserine(PKA)HMM predict
568Phosphothreonine(MAPK)HMM predict
635Phosphoserine(CK2)HMM predict
636Phosphoserine(CK2)HMM predict
636PhosphoserineHMM predict
641Phosphotyrosine(EGFR)HMM predict
641Phosphotyrosine(INSR)HMM predict
641Phosphotyrosine(Syk)HMM predict
705Phosphothreonine(CDC2)HMM predict
1045Phosphothreonine(CDC2)HMM predict
1057N-linkedHMM predict
1100O-linkedHMM predict
1103O-linkedHMM predict
1103Phosphothreonine(MAPK)HMM predict
1103Phosphothreonine(CDK)HMM predict
1135Phosphoserine(IKK)HMM predict
1144Phosphoserine(CDC2)HMM predict
1154Phosphotyrosine(Abl)HMM predict
1158O-linkedHMM predict
1158Phosphoserine(PKB)HMM predict
1162O-linkedHMM predict
1163O-linkedHMM predict
1163Phosphothreonine(CDC2)HMM predict
1168Phosphothreonine(PKC)HMM predict
1175Phosphoserine(CDC2)HMM predict
1203O-linkedHMM predict
1205O-linkedHMM predict
1210Phosphoserine(ATM)HMM predict
1233Phosphoserine(PKG)HMM predict
1265Phosphotyrosine(SRC)HMM predict
1267O-linkedHMM predict
1271O-linkedHMM predict
1271Phosphoserine(IKK)HMM predict
1273O-linkedHMM predict
1277N-linkedHMM predict
1280Phosphoserine(CK1)HMM predict
1280Phosphoserine(CK2)HMM predict
1283Phosphoserine(CK1)HMM predict
1313O-linkedHMM predict
1318O-linkedHMM predict
1383Phosphoserine(ATM)HMM predict
1387O-linkedHMM predict
1387Phosphothreonine(MAPK)HMM predict
1389O-linkedHMM predict
1423O-linkedHMM predict
1423Phosphothreonine(MAPK)HMM predict
1440Phosphoserine(ATM)HMM predict
1462O-linkedHMM predict
1501Phosphoserine(CDC2)HMM predict
1501Phosphoserine(CDK)HMM predict
1508Phosphoserine(CK2)HMM predict
1534Phosphoserine(CDC2)HMM predict
1534Phosphoserine(CDK)HMM predict
1544Phosphoserine(CK1)HMM predict
1556Phosphoserine(IKK)HMM predict
1559Phosphoserine(CDC2)HMM predict
1581O-linkedHMM predict
1602O-linkedHMM predict
1615Phosphothreonine(PKC)HMM predict
1622Phosphoserine(CK1)HMM predict
1677Phosphoserine(CDC2)HMM predict
1685PhosphoserineHMM predict
1692Phosphoserine(CK1)HMM predict
1699Phosphothreonine(MAPK)HMM predict
1703O-linkedHMM predict
1703Phosphothreonine(MAPK)HMM predict
1705O-linkedHMM predict
1760Phosphoserine(ATM)HMM predict
1760Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015073
  • Location:chr19 43089707-43390845
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 43081237 43081450 213 8364
CTCF CD4GSE12889 43085162 43085423 261 4415
CTCF CD4SISSRdata 43081237 43081450 213 8364
CTCF CD4SISSRdata 43085162 43085423 261 4415
CTCF JurkatGSE12889 43085146 43085382 236 4444
CTCF G2GSE9613 43080996 43081355 359 8532
ETS1 JurkatGSE17954 43088815 43090269 1454 166
PHF8 HeLaGSE20725 43088736 43090273 1537 203
TFAP2C MCF7GSE21234 43089295 43089806 511 157
hScc1 BcellGSE12603 43080996 43081378 382 8521
hScc1 BcellGSE12603 43085010 43085504 494 4451
hScc1 CdLSGSE12603 43080783 43081378 595 8627
hScc1 CdLSGSE12603 43085010 43085615 605 4395
p130 SenescentGSE19898 43089218 43089739 521 229
p130 shRbQuiescentGSE19898 43089332 43089833 501 125
p130 shRbSenescentGSE19898 43089343 43089728 385 172
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 43392171 43392494 323 1487
p130 QuiescentGSE19898 43392052 43392343 291 1352
p130 shRbQuiescentGSE19898 43392062 43392612 550 1492
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 43181715 43182679 964 0
CBP T30-glioblastomaGSE21026 43252807 43253598 791 0
CTCF CD4GSE12889 43231763 43232012 249 0
CTCF CD4GSE12889 43278201 43278471 270 0
CTCF CD4SISSRdata 43231763 43232012 249 0
CTCF CD4SISSRdata 43278201 43278471 270 0
CTCF JurkatGSE12889 43317145 43317361 216 0
CTCF G2GSE9613 43217343 43217575 232 0
CTCF G2GSE9613 43277882 43278549 667 0
CTCF G2GSE9613 43317214 43317608 394 0
CTCF G2GSE9613 43335118 43335530 412 0
CTCF G2GSE9613 43346240 43346626 386 0
ER MCF7GSE19013 43114612 43115339 727 0
ER MCF7GSE19013 43240419 43241341 922 0
FOXA1 MCF7GSE15244 43123855 43124843 988 0
FOXA1 MCF7GSE15244 43240487 43241154 667 0
FOXA1 MCF7GSE15244 43262350 43262740 390 0
FOXA1 MCF7GSE15244 43376276 43376812 536 0
Fos K562GSE19551 43186846 43187486 640 0
Fos K562GSE19551 43321670 43322089 419 0
Fos K562GSE19551 43332074 43332545 471 0
FoxA1 MCF7MACSdata 43262577 43262838 261 0
Gata1 K562GSE18868 43305126 43305728 602 0
Gata1 K562GSE18868 43335279 43335893 614 0
Gata2 K562GSE18868 43304954 43305737 783 0
Gata2 K562GSE18868 43335146 43335893 747 0
Myc K562GSE19551 43304970 43305741 771 0
Myc K562GSE19551 43317120 43317661 541 0
NFkBII GM12878GSE19485 43228048 43230114 2066 0
NFkBII GM12878GSE19485 43230225 43232401 2176 0
Nanog hESGSE18292 43230522 43230814 292 0
Nanog hESGSE18292 43238231 43238497 266 0
Oct1 H2O2-HelaGSE14283 43144673 43144709 36 0
Oct1 H2O2-HelaGSE14283 43165727 43165755 28 0
Oct1 H2O2-HelaGSE14283 43356388 43356415 27 0
Oct1 HelaGSE14283 43165728 43165779 51 0
Oct1 HelaGSE14283 43167045 43167095 50 0
Oct1 HelaGSE14283 43318784 43318849 65 0
Oct1 HelaGSE14283 43379750 43379787 37 0
P300 T0-glioblastomaGSE21026 43253128 43253693 565 0
P300 T30-glioblastomaGSE21026 43089220 43090259 1039 0
P300 T30-glioblastomaGSE21026 43252949 43253505 556 0
P300 T30-glioblastomaGSE21026 43355627 43356310 683 0
RARA MCF7GSE15244 43123855 43124881 1026 0
Rb GrowingGSE19898 43130963 43131274 311 0
Rb QuiescentGSE19898 43114430 43114771 341 0
Rb QuiescentGSE19898 43114829 43115093 264 0
Rb SenescentGSE19898 43089288 43090370 1082 0
TFAP2C MCF7GSE21234 43123820 43125344 1524 0
TFAP2C MCF7GSE21234 43148451 43149022 571 0
TFAP2C MCF7GSE21234 43164205 43165177 972 0
TFAP2C MCF7GSE21234 43174025 43174898 873 0
TFAP2C MCF7GSE21234 43215915 43216680 765 0
TFAP2C MCF7GSE21234 43240407 43241388 981 0
TFAP2C MCF7GSE21234 43256731 43257146 415 0
TFAP2C MCF7GSE21234 43347605 43347977 372 0
TFAP2C MCF7GSE21234 43386398 43387067 669 0
USF1 HepG2E 43187211 43187876 665 0
USF2 HepG2E 43187211 43187840 629 0
VDR GM10861-stimGSE22484 43160019 43163947 3928 0
hScc1 BcellGSE12603 43157519 43158213 694 0
hScc1 BcellGSE12603 43171201 43171448 247 0
hScc1 BcellGSE12603 43216196 43216713 517 0
hScc1 BcellGSE12603 43228562 43229370 808 0
hScc1 BcellGSE12603 43230061 43230377 316 0
hScc1 BcellGSE12603 43237202 43237487 285 0
hScc1 BcellGSE12603 43276264 43276514 250 0
hScc1 BcellGSE12603 43278097 43278549 452 0
hScc1 BcellGSE12603 43317214 43317438 224 0
hScc1 BcellGSE12603 43324881 43325994 1113 0
hScc1 BcellGSE12603 43334898 43335815 917 0
hScc1 BcellGSE12603 43338592 43338780 188 0
hScc1 BcellGSE12603 43378238 43378755 517 0
hScc1 BcellGSE12603 43384209 43384683 474 0
hScc1 BcellGSE12603 43388271 43389157 886 0
p130 QuiescentGSE19898 43377926 43378116 190 0
p130 SenescentGSE19898 43160447 43160844 397 0
p130 SenescentGSE19898 43180365 43180749 384 0
p130 shRbQuiescentGSE19898 43185681 43186804 1123 0
p130 shRbSenescentGSE19898 43114431 43114812 381 0
p130 shRbSenescentGSE19898 43185929 43186521 592 0
p63 keratinocytesGSE17611 43148292 43149430 1138 0
p63 keratinocytesGSE17611 43161907 43163006 1099 0
p63 keratinocytesGSE17611 43344244 43345292 1048 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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