AutismKB 2.0

Annotation Detail for IQSEC2


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Basic Information Top
Gene Symbol:IQSEC2 ( BRAG1,KIAA0522,MRX1 )
Gene Full Name: IQ motif and Sec7 domain 2
Band: Xp11.22
Quick LinksEntrez ID:23096; OMIM: 300522; Uniprot ID:IQEC2_HUMAN; ENSEMBL ID: ENSG00000124313; HGNC ID: 29059
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
82Phosphoserine (By similarity).
89Phosphotyrosine (By similarity).
383Phosphoserine (By similarity).
402Phosphoserine (By similarity).
611Phosphotyrosine (By similarity).
923Phosphotyrosine (By similarity).
1119Phosphotyrosine (By similarity).
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015075
  • Location:chrX 53278783-53327520
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 53330654 53330934 280 3274
CTCF CD4SISSRdata 53330654 53330934 280 3274
CTCF G2GSE9613 53329657 53330891 1234 2754
CTCF G2GSE9613 53333326 53334096 770 6191
CTCF G2GSE9613 53338780 53339022 242 11381
Oct1 HelaGSE14283 53331025 53331052 27 3518
hScc1 BcellGSE12603 53330462 53330822 360 3122
hScc1 G2GSE9613 53333730 53334953 1223 6821
p130 SenescentGSE19898 53327710 53327931 221 300
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018