AutismKB 2.0

Annotation Detail for TNRC6B


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Basic Information Top
Gene Symbol:TNRC6B ( KIAA1093 )
Gene Full Name: trinucleotide repeat containing 6B
Band: 22q13.1
Quick LinksEntrez ID:23112; OMIM: 610740; Uniprot ID:TNR6B_HUMAN; ENSEMBL ID: ENSG00000100354; HGNC ID: 29190
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
406Phosphoserine.
407Phosphothreonine.
1432Phosphoserine.
1816Phosphoserine.
Location(AA) Modifications Resource
173N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
143Phosphothreonine(CDK)HMM predict
143Phosphothreonine(CDC2)HMM predict
145Phosphoserine(IKK)HMM predict
161Phosphoserine(CK2)HMM predict
161O-linkedHMM predict
162Phosphoserine(CK2)HMM predict
163Phosphoserine(CK2)HMM predict
164Phosphoserine(CK1)HMM predict
165O-linkedHMM predict
173N-linkedHMM predict
191O-linkedHMM predict
245O-linkedHMM predict
245Phosphothreonine(CDC2)HMM predict
262Phosphothreonine(PKA)HMM predict
296PhenylalanineHMM predict
297PhenylalanineHMM predict
298PhenylalanineHMM predict
299PhenylalanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001024843
  • Location:chr22 38770766-39061756
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 38769742 38770729 987 531
Nanog hESGSE18292 38769946 38770323 377 632
PHF8 HeLaGSE20725 38769694 38771823 2129 8
PHF8 Hs68plusFBSGSE20725 38769495 38771961 2466 39
RARA MCF7GSE15244 38766622 38767496 874 3708
RARA MCF7GSE15244 38769742 38770583 841 604
TAF k562GSE8489 38769742 38770784 1042 504
TFAP2C MCF7GSE21234 38766835 38767449 614 3625
p130 shRbQuiescentGSE19898 38769756 38770259 503 759
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 38881876 38882553 677 0
FOXA1 MCF7GSE15244 38903010 38903802 792 0
Fos K562GSE19551 38781303 38782022 719 0
Fos K562GSE19551 38881791 38882428 637 0
P300 T0-glioblastomaGSE21026 38881864 38882785 921 0
P300 T30-glioblastomaGSE21026 38881752 38882693 941 0
P300 T30-glioblastomaGSE21026 38902933 38904610 1677 0
PolII HeLaGSE12783 38903423 38904257 834 0
TFAP2C MCF7GSE21234 38834028 38834366 338 0
USF1 HepG2E 38902734 38904252 1518 0
USF2 HepG2E 38902814 38904226 1412 0
hScc1 BcellGSE12603 38771318 38771596 278 0
hScc1 BcellGSE12603 38776185 38776658 473 0
hScc1 CdLSGSE12603 38776148 38776734 586 0
p130 SenescentGSE19898 38770745 38770931 186 0
p130 shRbQuiescentGSE19898 38770690 38771005 315 0
p130 shRbSenescentGSE19898 38771409 38771579 170 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 19898466
hsa-let-7a hsa-let-7a-2 11 19898466
hsa-let-7a hsa-let-7a-3 22 19898466
hsa-let-7a hsa-let-7a-1 9 17167072
hsa-let-7a hsa-let-7a-2 11 17167072
hsa-let-7a hsa-let-7a-3 22 17167072
hsa-let-7a hsa-let-7a-1 9 19398495
hsa-let-7a hsa-let-7a-2 11 19398495
hsa-let-7a hsa-let-7a-3 22 19398495
hsa-let-7a* hsa-let-7a-1 9 19898466
hsa-let-7a* hsa-let-7a-3 22 19898466
hsa-let-7a* hsa-let-7a-1 9 17167072
hsa-let-7a* hsa-let-7a-3 22 17167072
hsa-let-7a* hsa-let-7a-1 9 19398495
hsa-let-7a* hsa-let-7a-3 22 19398495
hsa-let-7b hsa-let-7b 22 19898466
hsa-let-7b hsa-let-7b 22 17167072
hsa-let-7b hsa-let-7b 22 19398495
hsa-let-7b* hsa-let-7b 22 19898466
hsa-let-7b* hsa-let-7b 22 17167072
hsa-let-7b* hsa-let-7b 22 19398495
hsa-let-7c hsa-let-7c 21 19898466
hsa-let-7c hsa-let-7c 21 17167072
hsa-let-7c hsa-let-7c 21 19398495
hsa-let-7c* hsa-let-7c 21 19898466
hsa-let-7c* hsa-let-7c 21 17167072
hsa-let-7c* hsa-let-7c 21 19398495
hsa-let-7d hsa-let-7d 9 19898466
hsa-let-7d hsa-let-7d 9 17167072
hsa-let-7d hsa-let-7d 9 19398495
hsa-let-7d* hsa-let-7d 9 19898466
hsa-let-7d* hsa-let-7d 9 17167072
hsa-let-7d* hsa-let-7d 9 19398495
hsa-let-7e hsa-let-7e 19 19898466
hsa-let-7e hsa-let-7e 19 17167072
hsa-let-7e hsa-let-7e 19 19398495
hsa-let-7e* hsa-let-7e 19 19898466
hsa-let-7e* hsa-let-7e 19 17167072
hsa-let-7e* hsa-let-7e 19 19398495
hsa-let-7f hsa-let-7f-1 9 19898466
hsa-let-7f hsa-let-7f-2 X 19898466
hsa-let-7f hsa-let-7f-1 9 17167072
hsa-let-7f hsa-let-7f-2 X 17167072
hsa-let-7f hsa-let-7f-1 9 19398495
hsa-let-7f hsa-let-7f-2 X 19398495
hsa-let-7f-1* hsa-let-7f-1 9 19898466
hsa-let-7f-1* hsa-let-7f-1 9 17167072
hsa-let-7f-1* hsa-let-7f-1 9 19398495
hsa-let-7f-2* hsa-let-7f-2 X 19898466
hsa-let-7f-2* hsa-let-7f-2 X 17167072
hsa-let-7f-2* hsa-let-7f-2 X 19398495
hsa-let-7g hsa-let-7g 3 19898466
hsa-let-7g hsa-let-7g 3 17167072
hsa-let-7g hsa-let-7g 3 19398495
hsa-let-7g* hsa-let-7g 3 19898466
hsa-let-7g* hsa-let-7g 3 17167072
hsa-let-7g* hsa-let-7g 3 19398495
hsa-let-7i hsa-let-7i 12 19898466
hsa-let-7i hsa-let-7i 12 17167072
hsa-let-7i hsa-let-7i 12 19398495
hsa-let-7i* hsa-let-7i 12 19898466
hsa-let-7i* hsa-let-7i 12 17167072
hsa-let-7i* hsa-let-7i 12 19398495
hsa-miR-124 hsa-mir-124-1 8 19898466
hsa-miR-124 hsa-mir-124-2 8 19898466
hsa-miR-124 hsa-mir-124-3 20 19898466
hsa-miR-124 hsa-mir-124-1 8 17167072
hsa-miR-124 hsa-mir-124-2 8 17167072
hsa-miR-124 hsa-mir-124-3 20 17167072
hsa-miR-125a-3p hsa-mir-125a 19 17167072
hsa-miR-125a-5p hsa-mir-125a 19 17167072
hsa-miR-125b hsa-mir-125b-1 11 17167072
hsa-miR-125b hsa-mir-125b-2 21 17167072
hsa-miR-125b-1* hsa-mir-125b-1 11 17167072
hsa-miR-125b-2* hsa-mir-125b-2 21 17167072
hsa-miR-128 hsa-mir-128-1 2 17167072
hsa-miR-128 hsa-mir-128-2 3 17167072
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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