AutismKB 2.0

Annotation Detail for HIC2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HIC2 ( HRG22,KIAA1020,ZBTB30,ZNF907 )
Gene Full Name: hypermethylated in cancer 2
Band: 22q11.21
Quick LinksEntrez ID:23119; OMIM: 607712; Uniprot ID:HIC2_HUMAN; ENSEMBL ID: ENSG00000169635; HGNC ID: 18595
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
148Phosphoserine(CDK)HMM predict
150MethylarginineHMM predict
162Phosphoserine(ATM)HMM predict
169Phosphoserine(CAMK2)HMM predict
197Phosphoserine(CK2)HMM predict
235N-linkedHMM predict
260Phosphothreonine(CDC2)HMM predict
260O-linkedHMM predict
260O-linkedHMM predict
260Phosphothreonine(MAPK)HMM predict
276Phosphoserine(CK1)HMM predict
276Phosphoserine(ATM)HMM predict
280Phosphoserine(ATM)HMM predict
285O-linkedHMM predict
296O-linkedHMM predict
348Phosphoserine(CDC2)HMM predict
385O-linkedHMM predict
388Phosphotyrosine(SRC)HMM predict
388Phosphotyrosine(Abl)HMM predict
393Phosphotyrosine(EGFR)HMM predict
406Phosphoserine(CAMK2)HMM predict
412Phosphoserine(CK1)HMM predict
414Phosphoserine(IKK)HMM predict
432Phosphotyrosine(Syk)HMM predict
442Phosphotyrosine(INSR)HMM predict
442Phosphotyrosine(EGFR)HMM predict
447S-palmitoylHMM predict
465Phosphothreonine(CK2)HMM predict
477Phosphotyrosine(INSR)HMM predict
514Phosphotyrosine(Syk)HMM predict
597LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015094
  • Location:chr22 20101692-20135747
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 20084175 20084873 698 17169
H3ac HepG2E 20085378 20087383 2005 15312
H3ac HepG2E 20100667 20100986 319 866
TFAP2C MCF7GSE21234 20086656 20087189 533 14770
hScc1 BcellGSE12603 20084175 20084873 698 17169
hScc1 CdLSGSE12603 20084175 20084599 424 17306
hScc1 CdLSGSE12603 20101097 20101495 398 397
hScc1 G2GSE9613 20084175 20084873 698 17169
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 20140662 20142085 1423 5626
FoxA1 MCF7MACSdata 20141500 20141919 419 5962
RARA MCF7GSE15244 20140662 20142085 1423 5626
RARG MCF7GSE15244 20140662 20142085 1423 5626
TFAP2C MCF7GSE21234 20141358 20142113 755 5988
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 20102646 20104332 1686 0
FOXA1 MCF7GSE15244 20120445 20121022 577 0
H3K4me2 HCT116GSE10453 20103073 20103971 898 0
H3ac HepG2E 20102478 20108607 6129 0
H3ac HepG2E 20117133 20117823 690 0
H3ac HepG2E 20118511 20119964 1453 0
H3ac HepG2E 20124276 20124973 697 0
Myc K562GSE19551 20102185 20102364 179 0
Myc K562GSE19551 20122405 20122571 166 0
RARA MCF7GSE15244 20104728 20105381 653 0
RARA MCF7GSE15244 20124276 20125635 1359 0
RARG MCF7GSE15244 20103185 20105236 2051 0
RARG MCF7GSE15244 20119211 20119848 637 0
RARG MCF7GSE15244 20124276 20124902 626 0
RARG MCF7GSE15244 20125150 20125534 384 0
TFAP2C MCF7GSE21234 20105138 20105852 714 0
TFAP2C MCF7GSE21234 20120519 20121568 1049 0
TFAP2C MCF7GSE21234 20124361 20127080 2719 0
USF2 HepG2E 20107601 20108570 969 0
hScc1 BcellGSE12603 20104332 20104523 191 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-205 hsa-mir-205 1 17475218
hsa-miR-21 hsa-mir-21 17 17475218
hsa-miR-21* hsa-mir-21 17 17475218
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved