AutismKB 2.0

Annotation Detail for MAST2


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Basic Information Top
Gene Symbol:MAST2 ( FLJ39200,KIAA0807,MAST205,MTSSK,RP4-533D7.1 )
Gene Full Name: microtubule associated serine/threonine kinase 2
Band: 1p34.1
Quick LinksEntrez ID:23139; OMIM: 612257; Uniprot ID:MAST2_HUMAN; ENSEMBL ID: ENSG00000086015; HGNC ID: 19035
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
74Phosphoserine.
148Phosphoserine.
151Phosphoserine (By similarity).
900Phosphoserine.
1503Phosphoserine.
1508Phosphothreonine.
Location(AA) Modifications Resource
151Phosphoserine (By similarity).Swiss-Prot 53.0
1503Phosphoserine.Swiss-Prot 53.0
1503PhosphoserinePhospho.ELM 6.0
1508Phosphothreonine.Swiss-Prot 53.0
1508PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
29Phosphoserine(ATM)HMM predict
108Phosphoserine(CK1)HMM predict
121Phosphoserine(CK1)HMM predict
151Phosphoserine(CK1)HMM predict
166Phosphoserine(IKK)HMM predict
166Phosphoserine(PKB)HMM predict
179O-linkedHMM predict
180O-linkedHMM predict
181O-linkedHMM predict
183O-linkedHMM predict
183O-linkedHMM predict
183Phosphoserine(IKK)HMM predict
185O-linkedHMM predict
191Phosphoserine(IKK)HMM predict
209Phosphoserine(CDC2)HMM predict
230Phosphoserine(PKG)HMM predict
230Phosphoserine(IKK)HMM predict
233O-linkedHMM predict
241O-linkedHMM predict
243O-linkedHMM predict
243Phosphothreonine(MAPK)HMM predict
245O-linkedHMM predict
245Phosphoserine(MAPK)HMM predict
246O-linkedHMM predict
246O-linkedHMM predict
247O-linkedHMM predict
247O-linkedHMM predict
247Phosphothreonine(PKC)HMM predict
251Phosphoserine(IKK)HMM predict
254Phosphoserine(CK1)HMM predict
299Phosphoserine(PKG)HMM predict
299Phosphoserine(PKB)HMM predict
299PhosphoserineHMM predict
301Phosphoserine(CDC2)HMM predict
301PhosphoserineHMM predict
343Phosphothreonine(CDC2)HMM predict
401Phosphoserine(CK1)HMM predict
403Phosphoserine(CK1)HMM predict
403PhosphoserineHMM predict
480Phosphoserine(IKK)HMM predict
481Phosphoserine(IKK)HMM predict
484Phosphoserine(CDC2)HMM predict
484Phosphoserine(IKK)HMM predict
487Phosphothreonine(CDC2)HMM predict
487Phosphothreonine(MAPK)HMM predict
487Phosphothreonine(CDK)HMM predict
493Phosphoserine(CK1)HMM predict
506Phosphothreonine(MAPK)HMM predict
506Phosphothreonine(CDK)HMM predict
691Phosphotyrosine(INSR)HMM predict
760Phosphoserine(CK1)HMM predict
773Phosphothreonine(PKC)HMM predict
812SulfotyrosineHMM predict
825Phosphoserine(CK2)HMM predict
853Phosphotyrosine(SRC)HMM predict
853Phosphotyrosine(Jak)HMM predict
867Phosphothreonine(MAPK)HMM predict
867PhosphothreonineHMM predict
871Phosphothreonine(PKC)HMM predict
874Phosphoserine(PKG)HMM predict
876Phosphoserine(CK1)HMM predict
876Phosphoserine(CK2)HMM predict
876PhosphoserineHMM predict
890O-linkedHMM predict
909Phosphoserine(PKA)HMM predict
909Phosphoserine(PKC)HMM predict
909Phosphoserine(PKG)HMM predict
909Phosphoserine(CAMK2)HMM predict
913Phosphoserine(CK2)HMM predict
914Phosphoserine(CK1)HMM predict
921O-linkedHMM predict
925Phosphothreonine(PKC)HMM predict
949Phosphothreonine(PKC)HMM predict
962Phosphothreonine(CDK)HMM predict
962PhosphothreonineHMM predict
970O-linkedHMM predict
992O-linkedHMM predict
995O-linkedHMM predict
995Phosphoserine(IKK)HMM predict
996Phosphoserine(CDC2)HMM predict
1068Phosphoserine(MAPK)HMM predict
1072O-linkedHMM predict
1072Phosphoserine(CDC2)HMM predict
1075Phosphoserine(MAPK)HMM predict
1075Phosphoserine(IKK)HMM predict
1078Phosphoserine(ATM)HMM predict
1078Phosphoserine(IKK)HMM predict
1078PhosphoserineHMM predict
1081Phosphoserine(IKK)HMM predict
1082N-linkedHMM predict
1085O-linkedHMM predict
1088Phosphoserine(CK1)HMM predict
1089Phosphoserine(CDC2)HMM predict
1089Phosphoserine(IKK)HMM predict
1089PhosphoserineHMM predict
1117Phosphothreonine(PKC)HMM predict
1187Phosphoserine(PKG)HMM predict
1189O-linkedHMM predict
1214Phosphoserine(CDK)HMM predict
1236Phosphothreonine(PKA)HMM predict
1252N-linkedHMM predict
1256Phosphoserine(CK1)HMM predict
1260Phosphoserine(IKK)HMM predict
1264O-linkedHMM predict
1264Phosphoserine(CDC2)HMM predict
1264Phosphoserine(CDK)HMM predict
1264Phosphoserine(ATM)HMM predict
1264Phosphoserine(IKK)HMM predict
1264PhosphoserineHMM predict
1266Phosphothreonine(CDK)HMM predict
1268O-linkedHMM predict
1272O-linkedHMM predict
1272Phosphoserine(CDC2)HMM predict
1272Phosphoserine(MAPK)HMM predict
1272Phosphoserine(CDK)HMM predict
1280Phosphotyrosine(Syk)HMM predict
1283Phosphothreonine(PKA)HMM predict
1293N-linkedHMM predict
1295Phosphoserine(ATM)HMM predict
1298O-linkedHMM predict
1299Phosphoserine(CDC2)HMM predict
1299Phosphoserine(CDK)HMM predict
1299Phosphoserine(IKK)HMM predict
1301Phosphoserine(CK1)HMM predict
1303Phosphoserine(CK1)HMM predict
1303Phosphoserine(ATM)HMM predict
1306Phosphoserine(CK1)HMM predict
1307O-linkedHMM predict
1307Phosphoserine(CDC2)HMM predict
1307Phosphoserine(CDK)HMM predict
1307Phosphoserine(IKK)HMM predict
1332Phosphoserine(CDC2)HMM predict
1332Phosphoserine(CDK)HMM predict
1332Phosphoserine(CDK)HMM predict
1337Phosphoserine(PKG)HMM predict
1337Phosphoserine(PKB)HMM predict
1340Phosphoserine(IKK)HMM predict
1344Phosphoserine(CDC2)HMM predict
1349O-linkedHMM predict
1349Phosphothreonine(CDC2)HMM predict
1349Phosphothreonine(CDK)HMM predict
1351O-linkedHMM predict
1351Phosphoserine(CDC2)HMM predict
1356O-linkedHMM predict
1356O-linkedHMM predict
1356O-linkedHMM predict
1358Phosphoserine(CDC2)HMM predict
1362O-linkedHMM predict
1362Phosphoserine(CDK)HMM predict
1362PhosphoserineHMM predict
1364O-linkedHMM predict
1364Phosphoserine(CDC2)HMM predict
1364Phosphoserine(ATM)HMM predict
1381Phosphoserine(ATM)HMM predict
1389Phosphoserine(PKA)HMM predict
1389PhosphoserineHMM predict
1393Phosphoserine(PKG)HMM predict
1393Phosphoserine(IKK)HMM predict
1399Phosphoserine(MAPK)HMM predict
1399Phosphoserine(CDK)HMM predict
1424Phosphothreonine(PKC)HMM predict
1429Phosphoserine(CAMK2)HMM predict
1429Phosphoserine(IKK)HMM predict
1447Phosphoserine(IKK)HMM predict
1491Phosphoserine(PKG)HMM predict
1491Phosphoserine(PKB)HMM predict
1503Phosphoserine(CK2)HMM predict
1504Phosphoserine(CK2)HMM predict
1504Phosphoserine(IKK)HMM predict
1530O-linkedHMM predict
1530Phosphoserine(ATM)HMM predict
1541Phosphoserine(CK2)HMM predict
1575Phosphoserine(CDC2)HMM predict
1575Phosphoserine(IKK)HMM predict
1585Phosphoserine(CDC2)HMM predict
1594O-linkedHMM predict
1594Phosphoserine(CK1)HMM predict
1594Phosphoserine(CK2)HMM predict
1596O-linkedHMM predict
1596Phosphoserine(IKK)HMM predict
1628O-linkedHMM predict
1631Phosphoserine(CDC2)HMM predict
1633O-linkedHMM predict
1635O-linkedHMM predict
1638O-linkedHMM predict
1638Phosphothreonine(MAPK)HMM predict
1638Phosphothreonine(CDK)HMM predict
1640O-linkedHMM predict
1640Phosphothreonine(MAPK)HMM predict
1641Phosphoserine(IKK)HMM predict
1644O-linkedHMM predict
1644Phosphoserine(ATM)HMM predict
1647O-linkedHMM predict
1669Phosphoserine(CDC2)HMM predict
1675Phosphothreonine(PKA)HMM predict
1688N-linkedHMM predict
1690Phosphothreonine(CDC2)HMM predict
1698Phosphoserine(CDC2)HMM predict
1718Phosphotyrosine(Syk)HMM predict
1722Phosphoserine(ATM)HMM predict
1742Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015112
  • Location:chr1 46041871-46274382
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc K562GSE19551 46040844 46041463 619 718
Oct4 hESGSE17917 46041591 46041835 244 159
PHF8 HeLaGSE20725 46040852 46042346 1494 273
PolII HeLaGSE12783 46040740 46042069 1329 467
Rb QuiescentGSE19898 46041579 46041696 117 234
p130 shRbQuiescentGSE19898 46041144 46041708 564 446
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 46275263 46275672 409 1085
CTCF CD4SISSRdata 46275263 46275672 409 1085
CTCF HelaGSE12889 46275347 46275596 249 1089
CTCF JurkatGSE12889 46275289 46275710 421 1117
CTCF G2GSE9613 46274746 46276116 1370 1049
Oct4 hESGSE17917 46275398 46275674 276 1154
TFAP2C MCF7GSE21234 46275044 46275715 671 997
hScc1 BcellGSE12603 46274940 46276116 1176 1146
hScc1 CdLSGSE12603 46274907 46276080 1173 1111
hScc1 G2GSE9613 46274907 46276291 1384 1217
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 46041864 46042430 566 0
CTCF G2GSE9613 46259177 46259350 173 0
CTCF G2GSE9613 46272863 46274102 1239 0
ER MCF7GSE19013 46091032 46091537 505 0
FoxA1 MCF7MACSdata 46110404 46110676 272 0
H3K4me3 colorectalcancer 46042468 46043286 818 0
H3ac HepG2E 46042391 46043286 895 0
H3ac HepG2E 46043598 46044083 485 0
Myc K562GSE19551 46102411 46102784 373 0
Myc hESGSE17917 46240946 46241239 293 0
Oct1 H2O2-HelaGSE14283 46053582 46053619 37 0
Oct1 H2O2-HelaGSE14283 46228997 46229026 29 0
Oct1 HelaGSE14283 46053582 46053618 36 0
P300 T30-glioblastomaGSE21026 46109563 46110902 1339 0
RARA MCF7GSE15244 46217519 46217788 269 0
SRF HepG2GSE8489 46196458 46196995 537 0
TAF k562GSE8489 46045251 46045771 520 0
TAF k562GSE8489 46065650 46065828 178 0
TFAP2C MCF7GSE21234 46110179 46110788 609 0
hScc1 BcellGSE12603 46041757 46042349 592 0
hScc1 BcellGSE12603 46050999 46051199 200 0
hScc1 BcellGSE12603 46272272 46273502 1230 0
hScc1 CdLSGSE12603 46081759 46082313 554 0
hScc1 G2GSE9613 46041757 46042577 820 0
p63 keratinocytesGSE17611 46190052 46190804 752 0
p63 keratinocytesGSE17611 46212994 46213810 816 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
728 mRNA MAST2 chr1 45981304 46213816 1359 mRNA chr1 46206585 46210447Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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