AutismKB 2.0

Annotation Detail for FLII


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Basic Information Top
Gene Symbol:FLII ( FLI,FLIL,Fli1,MGC39265 )
Gene Full Name: flightless I homolog (Drosophila)
Band: 17p11.2
Quick LinksEntrez ID:2314; OMIM: 600362; Uniprot ID:FLII_HUMAN; ENSEMBL ID: ENSG00000177731; HGNC ID: 3750
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
21N6-acetyllysine.
406Phosphoserine.
436Phosphoserine (By similarity).
856Phosphoserine.
Location(AA) Modifications Resource
1N-acetylmethionine.Swiss-Prot 53.0
406Phosphoserine.Swiss-Prot 53.0
436Phosphoserine (By similarity).Swiss-Prot 53.0
436PhosphoserinePhospho.ELM 6.0
856Phosphoserine.Swiss-Prot 53.0
856PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
16Phosphoserine(ATM)HMM predict
41N-linkedHMM predict
67N-linkedHMM predict
90Phosphoserine(PKG)HMM predict
149N-linkedHMM predict
165Phosphoserine(PKA)HMM predict
213Phosphoserine(IKK)HMM predict
252N-linkedHMM predict
256N-linkedHMM predict
339S-palmitoylHMM predict
409O-linkedHMM predict
409O-linkedHMM predict
436Phosphoserine(PKG)HMM predict
540Phosphoserine(CK1)HMM predict
578Phosphothreonine(PKC)HMM predict
611O-linkedHMM predict
818Phosphothreonine(PKC)HMM predict
820O-linkedHMM predict
1062N-linkedHMM predict
1154Phosphotyrosine(Syk)HMM predict
1160Phosphotyrosine(INSR)HMM predict
1205Phosphotyrosine(SRC)HMM predict
1205Phosphotyrosine(Syk)HMM predict
1268LeucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002018
  • Location:chr17 18088879-18102779
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 18102895 18102936 41 136
Oct1 HelaGSE14283 18102896 18102936 40 137
PHF8 293TGSE20725 18102149 18103479 1330 35
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 18092352 18092587 235 0
CTCF CD4SISSRdata 18092352 18092587 235 0
CTCF G2GSE9613 18091742 18092837 1095 0
CTCF G2GSE9613 18102285 18102941 656 0
PHF8 HeLaGSE20725 18101824 18103231 1407 0
PHF8 Hs68minusFBSGSE20725 18101751 18103043 1292 0
PHF8 Hs68plusFBSGSE20725 18101706 18103242 1536 0
TFAP2C MCF7GSE21234 18091102 18091711 609 0
TFAP2C MCF7GSE21234 18101174 18101953 779 0
hScc1 BcellGSE12603 18091766 18092837 1071 0
hScc1 BcellGSE12603 18101994 18103006 1012 0
hScc1 CdLSGSE12603 18092115 18092702 587 0
hScc1 G2GSE9613 18092083 18092917 834 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018