AutismKB 2.0

Annotation Detail for FLOT2


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Basic Information Top
Gene Symbol:FLOT2 ( ECS-1,ECS1,ESA,ESA1,M17S1 )
Gene Full Name: flotillin 2
Band: 17q11.2
Quick LinksEntrez ID:2319; OMIM: 131560; Uniprot ID:FLOT2_HUMAN; ENSEMBL ID: ENSG00000132589; HGNC ID: 3758
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
241Phosphotyrosine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
30Phosphothreonine(PKC)HMM predict
30Phosphothreonine(CK2)HMM predict
75Phosphotyrosine(Syk)HMM predict
109Phosphotyrosine(Syk)HMM predict
178Phosphoserine(CK1)HMM predict
236Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004475
  • Location:chr17 24230483-24248840
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 24223880 24224685 805 6201
Oct1 HelaGSE14283 24225391 24225484 93 5046
Oct1 HelaGSE14283 24226228 24226259 31 4240
Oct1 HelaGSE14283 24230182 24230218 36 284
TAFII hESGSE17917 24230194 24230659 465 57
hScc1 BcellGSE12603 24230247 24230523 276 99
hScc1 CdLSGSE12603 24230247 24230644 397 38
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 24230315 24231195 880 0
CTCF G2GSE9613 24248638 24249001 363 0
Myc hESGSE17917 24248610 24248963 353 0
NFkBII GM12878GSE19485 24238418 24240676 2258 0
NFkBII GM12892GSE19485 24238516 24239890 1374 0
Oct1 H2O2-HelaGSE14283 24244788 24244815 27 0
Oct1 HelaGSE14283 24244787 24244818 31 0
Rb GrowingGSE19898 24248235 24248429 194 0
SRF HelaGSE8489 24242337 24242890 553 0
SRF k562GSE8489 24242337 24242652 315 0
TAF HelaGSE8489 24242337 24242890 553 0
TAF k562GSE8489 24242337 24242652 315 0
hScc1 BcellGSE12603 24233498 24233849 351 0
hScc1 BcellGSE12603 24248420 24249037 617 0
p63 keratinocytesGSE17611 24231451 24232354 903 0
p63 keratinocytesGSE17611 24247746 24249325 1579 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-495 hsa-mir-495 14 21258409
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018