AutismKB 2.0

Annotation Detail for CYFIP1


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Basic Information Top
Gene Symbol:CYFIP1 ( FLJ45151,P140SRA-1,SHYC,SRA1 )
Gene Full Name: cytoplasmic FMR1 interacting protein 1
Band: 15q11.2
Quick LinksEntrez ID:23191; OMIM: 606322; Uniprot ID:CYFP1_HUMAN; ENSEMBL ID: ENSG00000068793; HGNC ID: 13759
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
108Phosphotyrosine.
1068Phosphothreonine.
1197N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
79Phosphotyrosine(INSR)HMM predict
79Phosphotyrosine(Syk)HMM predict
79Phosphotyrosine(Abl)HMM predict
188Phosphotyrosine(Syk)HMM predict
203Phosphoserine(IKK)HMM predict
321Phosphothreonine(PKC)HMM predict
328N-linkedHMM predict
336O-linkedHMM predict
340Phosphoserine(CDC2)HMM predict
435Phosphotyrosine(Syk)HMM predict
442N-linkedHMM predict
443Phosphotyrosine(INSR)HMM predict
443SulfotyrosineHMM predict
491Phosphothreonine(PKC)HMM predict
579Phosphothreonine(PKC)HMM predict
607N-linkedHMM predict
616S-palmitoylHMM predict
746Phosphotyrosine(Syk)HMM predict
773Phosphoserine(PKG)HMM predict
794Phosphoserine(CK1)HMM predict
831N-linkedHMM predict
858N-linkedHMM predict
862N-linkedHMM predict
887Phosphotyrosine(Jak)HMM predict
951Phosphothreonine(PKC)HMM predict
967Phosphotyrosine(INSR)HMM predict
967Phosphotyrosine(Syk)HMM predict
1015Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001033028
  • Location:chr15 20507195-20555042
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 20533042 20534676 1634 0
CBP JurkatGSE17954 20543397 20544782 1385 0
Myc K562GSE19551 20536062 20536350 288 0
Oct1 HelaGSE14283 20550483 20550516 33 0
SRF GMOGSE8489 20506947 20507570 623 0
STAT1 IFNSISSRdata 20528333 20529214 881 0
TFAP2C MCF7GSE21234 20519983 20520433 450 0
TFAP2C MCF7GSE21234 20522188 20522811 623 0
TFAP2C MCF7GSE21234 20528413 20529043 630 0
hScc1 BcellGSE12603 20508061 20508713 652 0
p130 SenescentGSE19898 20536142 20536389 247 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8503 mRNA CYFIP1 chr15 20507195 20557384 595 mRNA NIPA2 chr15 20556789 20585849Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018