AutismKB 2.0

Annotation Detail for XPO6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:XPO6 ( EXP6,FLJ22519,KIAA0370,RANBP20 )
Gene Full Name: exportin 6
Band: 16p11.2
Quick LinksEntrez ID:23214; OMIM: 608411; Uniprot ID:XPO6_HUMAN; ENSEMBL ID: ENSG00000169180; HGNC ID: 19733
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
199Phosphoserine.
201Phosphothreonine.
204Phosphothreonine.
208Phosphoserine.
210Phosphothreonine.
214Phosphoserine.
224Phosphoserine.
Location(AA) Modifications Resource
204Phosphothreonine.Swiss-Prot 53.0
204PhosphothreoninePhospho.ELM 6.0
208Phosphoserine.Swiss-Prot 53.0
208PhosphoserinePhospho.ELM 6.0
214Phosphoserine.Swiss-Prot 53.0
214PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
59SulfotyrosineHMM predict
59Phosphotyrosine(INSR)HMM predict
139Phosphoserine(CDC2)HMM predict
204Phosphothreonine(MAPK)HMM predict
204PhosphothreonineHMM predict
204O-linkedHMM predict
208O-linkedHMM predict
208Phosphoserine(CDK)HMM predict
210O-linkedHMM predict
211Phosphoserine(IKK)HMM predict
224Phosphoserine(CDK)HMM predict
224Phosphoserine(CDC2)HMM predict
244Phosphotyrosine(EGFR)HMM predict
265Phosphoserine(IKK)HMM predict
267Phosphothreonine(CDK)HMM predict
293N-linkedHMM predict
298N-linkedHMM predict
388Phosphoserine(PKB)HMM predict
540N-linkedHMM predict
545N-linkedHMM predict
647Phosphothreonine(PKC)HMM predict
798N-linkedHMM predict
931Phosphoserine(MAPK)HMM predict
1115N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015171
  • Location:chr16 28016816-28130690
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 28137030 28137357 327 6503
CTCF CD4SISSRdata 28137030 28137357 327 6503
ETS1 JurkatGSE17954 28130527 28131515 988 331
Myc K562GSE19551 28138176 28138477 301 7636
Oct1 H2O2-HelaGSE14283 28135072 28135101 29 4396
P300 T0-glioblastomaGSE21026 28130599 28131396 797 307
Rb shRbSenescenceGSE19898 28131049 28131405 356 537
USF1 HepG2E 28135562 28136062 500 5122
VDR GM10855-UnstimGSE22484 28130358 28131694 1336 336
VDR GM10861-stimGSE22484 28130632 28131751 1119 501
hScc1 CdLSGSE12603 28130587 28131089 502 148
p130 QuiescentGSE19898 28130992 28131250 258 431
p130 SenescentGSE19898 28130952 28131356 404 464
p130 shRbQuiescentGSE19898 28130771 28131523 752 457
p130 shRbSenescentGSE19898 28130960 28131315 355 447
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 28006083 28006486 403 10532
CTCF G2GSE9613 28009581 28010168 587 6942
CTCF G2GSE9613 28016445 28016635 190 277
NRSF mAbJurkat 28006665 28007170 505 9899
NRSF mAbJurkat 28008856 28009068 212 7855
NRSF-mono JurkatQuESTdata 28006571 28007175 604 9944
NRSF-poly JurkatQuESTdata 28006602 28007090 488 9971
TFAP2C MCF7GSE21234 28011325 28012305 980 5002
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 28112402 28113429 1027 0
CTCF CD4GSE12889 28055774 28056189 415 0
CTCF CD4GSE12889 28068039 28068301 262 0
CTCF CD4GSE12889 28127773 28127952 179 0
CTCF CD4SISSRdata 28055774 28056189 415 0
CTCF CD4SISSRdata 28068039 28068301 262 0
CTCF CD4SISSRdata 28127773 28127952 179 0
CTCF G2GSE9613 28017859 28018285 426 0
CTCF G2GSE9613 28023363 28023498 135 0
CTCF G2GSE9613 28026870 28027408 538 0
CTCF G2GSE9613 28121235 28121574 339 0
FOXA1 MCF7GSE15244 28101995 28102850 855 0
FoxA1 MCF7MACSdata 28068395 28068578 183 0
FoxA1 MCF7MACSdata 28070075 28070204 129 0
FoxA1 MCF7MACSdata 28102289 28102559 270 0
H3K4me2 HCT116GSE10453 28129127 28129659 532 0
H3K4me3 colorectalcancer 28129056 28129659 603 0
H3ac HepG2E 28128986 28129992 1006 0
NFkBII GM12878GSE19485 28098867 28101556 2689 0
NFkBII GM12892GSE19485 28098988 28100820 1832 0
Oct1 HelaGSE14283 28119210 28119241 31 0
P300 T30-glioblastomaGSE21026 28099554 28101138 1584 0
P300 T30-glioblastomaGSE21026 28112355 28113554 1199 0
P300 T30-glioblastomaGSE21026 28129283 28131803 2520 0
PHF8 Hs68plusFBSGSE20725 28129695 28131491 1796 0
USF1 HepG2E 28100491 28101370 879 0
VDR GM10861-UnstimGSE22484 28129340 28131644 2304 0
hScc1 BcellGSE12603 28059686 28059938 252 0
hScc1 BcellGSE12603 28085700 28085984 284 0
hScc1 BcellGSE12603 28111927 28112771 844 0
hScc1 CdLSGSE12603 28107145 28107751 606 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-122 hsa-mir-122 18 19296470
hsa-miR-122* hsa-mir-122 18 19296470
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
131 Unknown MicroArray miR-1 XPO6 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000169180 "cardiac and skeletal muscles, cardiogenesis" n_a n_a "leukocyte, lymphocyte, macrophage, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved