AutismKB 2.0

Annotation Detail for ARC


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Basic Information Top
Gene Symbol:ARC ( Arg3.1,KIAA0278 )
Gene Full Name: activity-regulated cytoskeleton-associated protein
Band: 8q24.3
Quick LinksEntrez ID:23237; OMIM: 612461; Uniprot ID:ARC_HUMAN; ENSEMBL ID: ENSG00000198576; HGNC ID: 648
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
45Phosphothreonine(PKC)HMM predict
78Phosphotyrosine(INSR)HMM predict
94S-palmitoylHMM predict
165Phosphotyrosine(Abl)HMM predict
167SulfotyrosineHMM predict
206O-linkedHMM predict
380Phosphothreonine(MAPK)HMM predict
387Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015193
  • Location:chr8 143689411-143692834
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 143702375 143702695 320 9701
CTCF CD4SISSRdata 143702375 143702695 320 9701
NRSF JurkatGSE13047 143708803 143712379 3576 17757
NRSF mAbJurkat 143708600 143709963 1363 16447
NRSF-mono JurkatQuESTdata 143709172 143711369 2197 17436
NRSF pAbJurkat 143708600 143709036 436 15984
NRSF pAbJurkat 143709688 143709963 275 16991
NRSF pAbJurkat 143710499 143710781 282 17806
NRSF-poly JurkatQuESTdata 143709796 143711545 1749 17836
p130 SenescentGSE19898 143692969 143693114 145 207
p130 shRbSenescentGSE19898 143692973 143693152 179 228
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 143687433 143687789 356 1801
CTCF CD4SISSRdata 143687433 143687789 356 1801
NRSF JurkatGSE13047 143679455 143680016 561 9676
NRSF-mono JurkatQuESTdata 143679496 143680103 607 9612
NRSF pAbJurkat 143672543 143672974 431 16653
NRSF pAbJurkat 143673322 143674267 945 15617
NRSF pAbJurkat 143679077 143679893 816 9927
NRSF-poly JurkatQuESTdata 143679383 143680105 722 9668
Rb shRbSenescenceGSE19898 143684230 143684469 239 5062
TFAP2C MCF7GSE21234 143675395 143676238 843 13595
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 143690003 143691462 1459 0
P300 T30-glioblastomaGSE21026 143692403 143693169 766 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018