AutismKB 2.0

Annotation Detail for DENND5A


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Basic Information Top
Gene Symbol:DENND5A ( FLJ22354,FLJ33829,FLJ43455,KIAA1091,RAB6IP1 )
Gene Full Name: DENN/MADD domain containing 5A
Band: 11p15.4
Quick LinksEntrez ID:23258; OMIM: NA; Uniprot ID:DEN5A_HUMAN; ENSEMBL ID: ENSG00000184014; HGNC ID: 19344
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
193Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015213
  • Location:chr11 9116948-9243446
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 9247662 9247883 221 4326
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 9115893 9116267 374 869
CTCF CD4SISSRdata 9115893 9116267 374 869
FOXA1 DLD1GSE12801 9116129 9117446 1317 161
FOXA1 MCF7GSE15244 9115820 9117144 1324 467
Nanog hESGSE18292 9099186 9099705 519 17503
RARG MCF7GSE15244 9115820 9117144 1324 467
hScc1 BcellGSE12603 9115495 9116578 1083 912
hScc1 CdLSGSE12603 9115532 9116423 891 971
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 9144073 9144208 135 0
CTCF CD4GSE12889 9182140 9182346 206 0
CTCF CD4GSE12889 9228472 9228645 173 0
CTCF CD4GSE12889 9243357 9243504 147 0
CTCF CD4SISSRdata 9144073 9144208 135 0
CTCF CD4SISSRdata 9182140 9182346 206 0
CTCF CD4SISSRdata 9228472 9228645 173 0
CTCF CD4SISSRdata 9243357 9243504 147 0
CTCF JurkatGSE12889 9144077 9144230 153 0
FOXA1 MCF7GSE15244 9122054 9122341 287 0
H3K4me3 colorectalcancer 9242010 9243143 1133 0
H3ac HepG2E 9242010 9242912 902 0
Myc K562GSE19551 9222726 9223060 334 0
NFkBII GM12878GSE19485 9186463 9190154 3691 0
NFkBII GM12892GSE19485 9188612 9190122 1510 0
NFkBII GM15510GSE19485 9188683 9189952 1269 0
NFkBII GM15510GSE19485 9241813 9242725 912 0
Nanog hESGSE18292 9209836 9210392 556 0
Oct1 H2O2-HelaGSE14283 9197113 9197142 29 0
Oct1 HelaGSE14283 9197113 9197140 27 0
Oct1 HelaGSE14283 9206834 9206862 28 0
Oct1 HelaGSE14283 9208814 9208842 28 0
Oct1 HelaGSE14283 9237298 9237392 94 0
Oct4 hESGSE21916 9209791 9210219 428 0
P300 T0-glioblastomaGSE21026 9197424 9198294 870 0
P300 T30-glioblastomaGSE21026 9116790 9117577 787 0
TAF HelaGSE8489 9242010 9242788 778 0
TAF k562GSE8489 9242126 9242848 722 0
TFAP2C MCF7GSE21234 9229504 9229813 309 0
hScc1 BcellGSE12603 9181951 9182421 470 0
hScc1 BcellGSE12603 9242578 9243628 1050 0
hScc1 CdLSGSE12603 9143872 9144157 285 0
hScc1 CdLSGSE12603 9242010 9243826 1816 0
hScc1 G2GSE9613 9242658 9243394 736 0
p130 SenescentGSE19898 9242620 9243089 469 0
p130 shRbQuiescentGSE19898 9242673 9243166 493 0
p63 keratinocytesGSE17611 9188511 9189545 1034 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018