AutismKB 2.0

Annotation Detail for KLHL18


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Basic Information Top
Gene Symbol:KLHL18 ( FLJ13703,FLJ61265,KIAA0795 )
Gene Full Name: kelch-like 18 (Drosophila)
Band: 3p21.31
Quick LinksEntrez ID:23276; OMIM: NA; Uniprot ID:KLH18_HUMAN; ENSEMBL ID: ENSG00000114648; HGNC ID: 29120
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
185S-palmitoylHMM predict
321Phosphotyrosine(INSR)HMM predict
329N-linkedHMM predict
333Phosphoserine(CK1)HMM predict
334Phosphoserine(CK1)HMM predict
354N-linkedHMM predict
368Phosphotyrosine(INSR)HMM predict
381Phosphoserine(CDK)HMM predict
450Phosphoserine(PKC)HMM predict
450Phosphoserine(PKA)HMM predict
492MethionineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_025010
  • Location:chr3 47299443-47363308
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 47298822 47299915 1093 75
Rb GrowingGSE19898 47299232 47299444 212 106
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 47367563 47367603 40 4275
Oct1 H2O2-HelaGSE14283 47367566 47367599 33 4274
Oct1 HelaGSE14283 47367566 47367604 38 4277
P300 T0-glioblastomaGSE21026 47363804 47364136 332 662
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47340844 47341088 244 0
CTCF CD4SISSRdata 47340844 47341088 244 0
CTCF G2GSE9613 47310902 47311080 178 0
CTCF G2GSE9613 47327336 47327481 145 0
CTCF G2GSE9613 47358713 47358988 275 0
CTCF G2GSE9613 47360048 47360344 296 0
FOXA1 MCF7GSE15244 47335181 47335859 678 0
H3ac HepG2E 47299783 47300067 284 0
Nanog hESGSE18292 47340849 47341081 232 0
Oct1 H2O2-HelaGSE14283 47316273 47316302 29 0
Oct1 H2O2-HelaGSE14283 47326665 47326695 30 0
Oct1 H2O2-HelaGSE14283 47340002 47340033 31 0
Oct1 HelaGSE14283 47326665 47326695 30 0
Oct1 HelaGSE14283 47340002 47340045 43 0
Sox2 hESGSE18292 47340886 47341076 190 0
hScc1 BcellGSE12603 47327262 47327481 219 0
hScc1 BcellGSE12603 47340627 47341014 387 0
hScc1 BcellGSE12603 47360012 47360418 406 0
hScc1 CdLSGSE12603 47340662 47341014 352 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018