AutismKB 2.0

Annotation Detail for WWC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:WWC1 ( FLJ10865,FLJ23369,HBEBP3,HBEBP36,KIAA0869,KIBRA )
Gene Full Name: WW and C2 domain containing 1
Band: 5q34
Quick LinksEntrez ID:23286; OMIM: 610533; Uniprot ID:KIBRA_HUMAN; ENSEMBL ID: ENSG00000113645; HGNC ID: 29435
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
899Phosphoserine (By similarity).
912Phosphothreonine.
922Phosphoserine.
923Phosphothreonine.
927Phosphoserine.
929Phosphothreonine.
931Phosphoserine.
975Phosphoserine; by PKC/PRKCZ.
978Phosphoserine; by PKC/PRKCZ.
1113ADDV motif.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015238
  • Location:chr5 167651669-167829333
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 167641841 167642018 177 9740
NFkBII GM10847GSE19485 167649208 167650209 1001 1961
NFkBII GM12878GSE19485 167649112 167650256 1144 1986
NFkBII GM12892GSE19485 167649144 167650247 1103 1974
NFkBII GM12892GSE19485 167650677 167652488 1811 87
NFkBII GM15510GSE19485 167649144 167651346 2202 1425
TFAP2C MCF7GSE21234 167647880 167648336 456 3562
hScc1 BcellGSE12603 167651301 167651787 486 126
p130 shRbQuiescentGSE19898 167650616 167651137 521 793
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 167796481 167796630 149 0
CTCF CD4SISSRdata 167796481 167796630 149 0
CTCF G2GSE9613 167651000 167652379 1379 0
CTCF G2GSE9613 167655323 167655657 334 0
CTCF G2GSE9613 167674192 167674380 188 0
CTCF G2GSE9613 167697426 167697571 145 0
CTCF G2GSE9613 167730574 167731036 462 0
CTCF G2GSE9613 167758886 167759201 315 0
CTCF G2GSE9613 167795741 167796025 284 0
CTCF G2GSE9613 167801144 167801545 401 0
CTCF G2GSE9613 167821670 167821852 182 0
CTCF G2GSE9613 167824194 167824537 343 0
ER MCF7GSE19013 167656316 167656817 501 0
ER MCF7GSE19013 167675351 167676536 1185 0
ER MCF7GSE19013 167707191 167708133 942 0
ER MCF7GSE19013 167712624 167713269 645 0
FOXA1 MCF7GSE15244 167674192 167676082 1890 0
NRSF pAbJurkat 167821701 167822281 580 0
P300 T30-glioblastomaGSE21026 167677133 167677872 739 0
RARA MCF7GSE15244 167675387 167676567 1180 0
RARA MCF7GSE15244 167761375 167761860 485 0
Rb GrowingGSE19898 167828581 167828728 147 0
TFAP2C MCF7GSE21234 167684428 167685197 769 0
TFAP2C MCF7GSE21234 167694211 167694777 566 0
TFAP2C MCF7GSE21234 167698783 167699083 300 0
TFAP2C MCF7GSE21234 167712696 167713264 568 0
TFAP2C MCF7GSE21234 167720052 167720551 499 0
TFAP2C MCF7GSE21234 167724589 167725092 503 0
TFAP2C MCF7GSE21234 167808663 167809173 510 0
VDR GM10861-stimGSE22484 167687879 167689158 1279 0
hScc1 BcellGSE12603 167796439 167796714 275 0
p130 SenescentGSE19898 167828484 167828724 240 0
p63 keratinocytesGSE17611 167749822 167750825 1003 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018