AutismKB 2.0

Annotation Detail for FBXW11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FBXW11 ( BTRC2,BTRCP2,FBW1B,FBXW1B,Fbw11,Hos,KIAA0696 )
Gene Full Name: F-box and WD repeat domain containing 11
Band: 5q35.1
Quick LinksEntrez ID:23291; OMIM: 605651; Uniprot ID:FBW1B_HUMAN; ENSEMBL ID: ENSG00000072803; HGNC ID: 13607
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
17Phosphoserine(ATM)HMM predict
52N-linkedHMM predict
69Phosphotyrosine(INSR)HMM predict
69Phosphotyrosine(SRC)HMM predict
84Phosphoserine(IKK)HMM predict
86PhosphoserineHMM predict
297Phosphoserine(IKK)HMM predict
528N-linkedHMM predict
532Phosphoserine(CDK)HMM predict
532Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012300
  • Location:chr5 171221160-171366481
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 171365843 171367161 1318 21
GABP k562GSE8489 171366654 171367093 439 392
H3K4me3 colorectalcancer 171366781 171367093 312 456
H3ac HepG2E 171366752 171367093 341 441
NRSF mAbJurkat 171366813 171367093 280 472
TAF HelaGSE8489 171366679 171367093 414 405
TFAP2C MCF7GSE21234 171369348 171369942 594 3164
p130 shRbQuiescentGSE19898 171366247 171367008 761 146
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 171217981 171218201 220 3070
CTCF CD4SISSRdata 171217981 171218201 220 3070
CTCF G2GSE9613 171205120 171206442 1322 15380
CTCF G2GSE9613 171208151 171208392 241 12889
CTCF G2GSE9613 171208928 171209247 319 12073
CTCF G2GSE9613 171217831 171218643 812 2924
Fos K562GSE19551 171211836 171212261 425 9112
NRSF pAbJurkat 171208151 171208392 241 12889
hScc1 BcellGSE12603 171217571 171218081 510 3335
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 171271759 171272118 359 0
CTCF CD4SISSRdata 171271759 171272118 359 0
CTCF G2GSE9613 171286846 171287021 175 0
CTCF G2GSE9613 171365954 171366882 928 0
GABP k562GSE8489 171363887 171365294 1407 0
H3K4me3 colorectalcancer 171364416 171365507 1091 0
H3ac HepG2E 171364300 171365696 1396 0
Myc K562GSE19551 171313550 171313930 380 0
NRSF JurkatGSE13047 171261323 171261763 440 0
NRSF mAbJurkat 171260182 171260580 398 0
NRSF-mono JurkatQuESTdata 171261322 171261762 440 0
NRSF-poly JurkatQuESTdata 171261310 171261739 429 0
Nanog hESGSE18292 171340352 171340642 290 0
P300 T30-glioblastomaGSE21026 171364448 171367466 3018 0
PHF8 293TGSE20725 171365168 171367750 2582 0
PHF8 HeLaGSE20725 171365302 171367327 2025 0
Rb SenescentGSE19898 171344656 171344985 329 0
TFAP2C MCF7GSE21234 171305886 171306421 535 0
TFAP2C MCF7GSE21234 171356634 171356982 348 0
hScc1 BcellGSE12603 171271532 171272053 521 0
hScc1 BcellGSE12603 171361861 171362252 391 0
hScc1 CdLSGSE12603 171267039 171267690 651 0
hScc1 CdLSGSE12603 171271193 171272053 860 0
hScc1 CdLSGSE12603 171361896 171362252 356 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 15131085
hsa-let-7b* hsa-let-7b 22 15131085
hsa-let-7e hsa-let-7e 19 15131085
hsa-let-7e* hsa-let-7e 19 15131085
hsa-miR-103 hsa-mir-103-2 20 15131085
hsa-miR-103 hsa-mir-103-1 5 15131085
hsa-miR-141 hsa-mir-141 12 18698484
hsa-miR-141 hsa-mir-141 12 15131085
hsa-miR-141* hsa-mir-141 12 18698484
hsa-miR-141* hsa-mir-141 12 15131085
hsa-miR-145 hsa-mir-145 5 15131085
hsa-miR-145* hsa-mir-145 5 15131085
hsa-miR-15a hsa-mir-15a 13 15131085
hsa-miR-15a* hsa-mir-15a 13 15131085
hsa-miR-15b hsa-mir-15b 3 15131085
hsa-miR-15b* hsa-mir-15b 3 15131085
hsa-miR-16 hsa-mir-16-1 13 15131085
hsa-miR-16 hsa-mir-16-2 3 15131085
hsa-miR-199b-3p hsa-mir-199b 9 15131085
hsa-miR-199b-5p hsa-mir-199b 9 15131085
hsa-miR-200a hsa-mir-200a 1 18698484
hsa-miR-200a* hsa-mir-200a 1 18698484
hsa-miR-200b hsa-mir-200b 1 18698484
hsa-miR-200b* hsa-mir-200b 1 18698484
hsa-miR-200c hsa-mir-200c 12 18698484
hsa-miR-200c* hsa-mir-200c 12 18698484
hsa-miR-205 hsa-mir-205 1 18698484
hsa-miR-23a hsa-mir-23a 19 15131085
hsa-miR-23a* hsa-mir-23a 19 15131085
hsa-miR-24 hsa-mir-24-1 9 15131085
hsa-miR-24 hsa-mir-24-2 19 15131085
hsa-miR-429 hsa-mir-429 1 18698484
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
226 mRNA repression TRUE miR-103-1 FBXW1B in vitro reporter gene assay (Luciferase) 15131085
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000072803 n_a n_a n_a "epithelium, squamous cell, lymphocyte" "benign tumour, malignant tumour, carcinoma, non-Hodgkin's, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved