AutismKB 2.0

Annotation Detail for UBR2


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Basic Information Top
Gene Symbol:UBR2 ( C6orf133,DKFZp686C08114,FLJ36357,KIAA0349,MGC71112,RP3-392M17.3,bA49A4.1,dJ242G1.1,dJ392M17.3 )
Gene Full Name: ubiquitin protein ligase E3 component n-recognin 2
Band: 6p21.1
Quick LinksEntrez ID:23304; OMIM: 609134; Uniprot ID:UBR2_HUMAN; ENSEMBL ID: ENSG00000024048; HGNC ID: 21289
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
110Phosphotyrosine(INSR)HMM predict
141Phosphothreonine(PKA)HMM predict
169N-linkedHMM predict
171Phosphoserine(CK2)HMM predict
227Phosphotyrosine(INSR)HMM predict
239Phosphotyrosine(Abl)HMM predict
251N-linkedHMM predict
348N-linkedHMM predict
384Phosphotyrosine(Jak)HMM predict
413Phosphoserine(PKG)HMM predict
413Phosphoserine(CAMK2)HMM predict
476Phosphoserine(PKA)HMM predict
626Phosphoserine(CK1)HMM predict
632Phosphotyrosine(SRC)HMM predict
746N-linkedHMM predict
747N-linkedHMM predict
773N-linkedHMM predict
854Phosphoserine(CK2)HMM predict
941N-linkedHMM predict
1005Phosphoserine(PKG)HMM predict
1006Phosphoserine(IKK)HMM predict
1006Phosphoserine(CDK)HMM predict
1009Phosphoserine(CDC2)HMM predict
1009Phosphoserine(MAPK)HMM predict
1009Phosphoserine(IKK)HMM predict
1009PhosphoserineHMM predict
1097Phosphothreonine(PKC)HMM predict
1139N-linkedHMM predict
1150Phosphotyrosine(Syk)HMM predict
1213S-palmitoylHMM predict
1236N-linkedHMM predict
1242N-linkedHMM predict
1251Phosphoserine(ATM)HMM predict
1348Phosphoserine(CK1)HMM predict
1399N-linkedHMM predict
1531Phosphoserine(CDC2)HMM predict
1616N-linkedHMM predict
1642Phosphoserine(ATM)HMM predict
1664Phosphotyrosine(INSR)HMM predict
1701Phosphotyrosine(INSR)HMM predict
1701SulfotyrosineHMM predict
1744N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015255
  • Location:chr6 42640035-42766886
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 42623353 42623591 238 16564
CTCF CD4SISSRdata 42623353 42623591 238 16564
CTCF G2GSE9613 42623182 42623989 807 16450
CTCF G2GSE9613 42639369 42639589 220 557
ETS1 JurkatGSE17954 42638938 42640496 1558 319
Oct1 HelaGSE14283 42625417 42625462 45 14596
P300 T30-glioblastomaGSE21026 42638989 42640408 1419 337
PHF8 293TGSE20725 42639320 42640454 1134 149
PHF8 HeLaGSE20725 42639400 42640508 1108 82
PHF8 Hs68minusFBSGSE20725 42639290 42640479 1189 151
PHF8 Hs68plusFBSGSE20725 42639170 42640785 1615 58
USF1 HepG2E 42622758 42622968 210 17173
USF1 HepG2E 42623228 42624908 1680 15968
USF2 HepG2E 42623517 42624491 974 16032
hScc1 BcellGSE12603 42623182 42624025 843 16432
hScc1 CdLSGSE12603 42622903 42623989 1086 16590
hScc1 G2GSE9613 42623146 42623903 757 16511
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 42737349 42737584 235 0
CTCF CD4SISSRdata 42737349 42737584 235 0
CTCF G2GSE9613 42639916 42640191 275 0
CTCF G2GSE9613 42640901 42641238 337 0
CTCF G2GSE9613 42737221 42737615 394 0
CTCF G2GSE9613 42766027 42766201 174 0
H3K4me2 HCT116GSE10453 42640688 42641238 550 0
H3K4me3 colorectalcancer 42640278 42641238 960 0
H3K4me3 colorectalcancer 42641595 42642072 477 0
H3ac HepG2E 42639333 42641238 1905 0
H3ac HepG2E 42641595 42642072 477 0
Myc K562GSE19551 42694379 42694707 328 0
Nanog ESGSE20650 42694354 42694873 519 0
Nanog hESGSE18292 42647469 42647706 237 0
Nanog hESGSE18292 42737311 42737761 450 0
Oct1 HelaGSE14283 42749841 42749868 27 0
TAF HelaGSE8489 42710486 42710703 217 0
TAF k562GSE8489 42640394 42641238 844 0
TAFII hESGSE17917 42737403 42737609 206 0
hScc1 BcellGSE12603 42737292 42737615 323 0
hScc1 CdLSGSE12603 42640867 42641238 371 0
hScc1 CdLSGSE12603 42737026 42737763 737 0
hScc1 G2GSE9613 42640901 42641238 337 0
hScc1 G2GSE9613 42737257 42737686 429 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22606 mRNA UBR2 chr6 42708516 42769220 325 EST chr6 42766964 42767289Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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