AutismKB 2.0

Annotation Detail for DMXL2


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Basic Information Top
Gene Symbol:DMXL2 ( FLJ26672,KIAA0856,RC3 )
Gene Full Name: Dmx-like 2
Band: 15q21.2
Quick LinksEntrez ID:23312; OMIM: 612186; Uniprot ID:DMXL2_HUMAN; ENSEMBL ID: ENSG00000104093; HGNC ID: 2938
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
451Phosphoserine (By similarity).
722Phosphotyrosine (By similarity).
944Phosphoserine.
945Phosphoserine.
949Phosphoserine.
1049N6-acetyllysine.
1140Phosphoserine.
1143Phosphoserine.
1400Phosphoserine.
1404Phosphoserine.
1857Phosphoserine.
1984Phosphoserine.
2399Phosphoserine (By similarity).
Location(AA) Modifications Resource
1400Phosphoserine.Swiss-Prot 53.0
1400PhosphoserinePhospho.ELM 6.0
1404Phosphoserine.Swiss-Prot 53.0
1404PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
220Phosphoserine(PKA)HMM predict
220Phosphoserine(PKG)HMM predict
220PhosphoserineHMM predict
221Phosphoserine(PKB)HMM predict
260S-palmitoylHMM predict
287O-linkedHMM predict
289O-linkedHMM predict
290Phosphoserine(IKK)HMM predict
326Phosphoserine(PKA)HMM predict
326Phosphoserine(PKG)HMM predict
415Phosphoserine(PKA)HMM predict
415Phosphoserine(PKG)HMM predict
434Phosphoserine(CK1)HMM predict
434Phosphoserine(ATM)HMM predict
451Phosphoserine(CK1)HMM predict
569N-linkedHMM predict
592Phosphoserine(ATM)HMM predict
596O-linkedHMM predict
596Phosphoserine(IKK)HMM predict
676Phosphothreonine(CDK)HMM predict
807Phosphoserine(CK1)HMM predict
807Phosphoserine(CK2)HMM predict
807Phosphoserine(ATM)HMM predict
812Phosphoserine(CK1)HMM predict
823Phosphoserine(ATM)HMM predict
883Phosphotyrosine(Syk)HMM predict
932Phosphoserine(CK1)HMM predict
935Phosphoserine(CK1)HMM predict
945O-linkedHMM predict
951O-linkedHMM predict
951Phosphoserine(IKK)HMM predict
953O-linkedHMM predict
987PhosphoserineHMM predict
994Phosphothreonine(PKA)HMM predict
1038N-linkedHMM predict
1061N-linkedHMM predict
1063Phosphoserine(CK1)HMM predict
1075O-linkedHMM predict
1140Phosphoserine(CK2)HMM predict
1160Phosphotyrosine(Jak)HMM predict
1245Phosphothreonine(CDK)HMM predict
1247O-linkedHMM predict
1288Phosphoserine(CK2)HMM predict
1310Phosphoserine(PKG)HMM predict
1341Phosphoserine(MAPK)HMM predict
1391Phosphothreonine(PKC)HMM predict
1400Phosphoserine(CAMK2)HMM predict
1400Phosphoserine(CK1)HMM predict
1400Phosphoserine(IKK)HMM predict
1400Phosphoserine(PKB)HMM predict
1400PhosphoserineHMM predict
1420Phosphotyrosine(INSR)HMM predict
1462Phosphoserine(CK2)HMM predict
1462Phosphoserine(ATM)HMM predict
1468Phosphotyrosine(SRC)HMM predict
1468Phosphotyrosine(Syk)HMM predict
1491N-linkedHMM predict
1497N-linkedHMM predict
1501Phosphotyrosine(INSR)HMM predict
1555Phosphoserine(IKK)HMM predict
1581O-linkedHMM predict
1768Phosphotyrosine(INSR)HMM predict
1857Phosphoserine(CDC2)HMM predict
1857Phosphoserine(CDK)HMM predict
1945N-linkedHMM predict
1954N-linkedHMM predict
2022Phosphothreonine(MAPK)HMM predict
2102Phosphotyrosine(INSR)HMM predict
2102Phosphotyrosine(SRC)HMM predict
2102Phosphotyrosine(Syk)HMM predict
2103Phosphoserine(IKK)HMM predict
2146Phosphoserine(PKA)HMM predict
2146Phosphoserine(PKG)HMM predict
2146Phosphoserine(IKK)HMM predict
2174Phosphoserine(CAMK2)HMM predict
2186Phosphoserine(ATM)HMM predict
2203O-linkedHMM predict
2211Phosphoserine(IKK)HMM predict
2217O-linkedHMM predict
2242Phosphothreonine(MAPK)HMM predict
2262Phosphoserine(IKK)HMM predict
2266O-linkedHMM predict
2278Phosphoserine(CK1)HMM predict
2278Phosphoserine(ATM)HMM predict
2303Phosphothreonine(PKA)HMM predict
2305Phosphoserine(CK1)HMM predict
2305PhosphoserineHMM predict
2313N-linkedHMM predict
2315O-linkedHMM predict
2363N-linkedHMM predict
2399Phosphoserine(IKK)HMM predict
2401N-linkedHMM predict
2434O-linkedHMM predict
2434Phosphothreonine(MAPK)HMM predict
2480Phosphoserine(CK1)HMM predict
2480Phosphoserine(CK2)HMM predict
2483Phosphoserine(CK1)HMM predict
2483Phosphoserine(CK2)HMM predict
2483Phosphoserine(CK2)HMM predict
2483Phosphoserine(ATM)HMM predict
2540Phosphoserine(CDC2)HMM predict
2571Phosphotyrosine(INSR)HMM predict
2599Phosphothreonine(MAPK)HMM predict
2634Phosphothreonine(PKC)HMM predict
2640Phosphoserine(PKA)HMM predict
2640Phosphoserine(PKG)HMM predict
2712PhosphoserineHMM predict
2722O-linkedHMM predict
2728O-linkedHMM predict
2730O-linkedHMM predict
2733O-linkedHMM predict
2735Phosphoserine(ATM)HMM predict
2742O-linkedHMM predict
2752O-linkedHMM predict
2770Phosphothreonine(PKA)HMM predict
2770Phosphothreonine(PKC)HMM predict
2836N-linkedHMM predict
2841N-linkedHMM predict
2865O-linkedHMM predict
2887Phosphoserine(CDC2)HMM predict
2887Phosphoserine(CDK)HMM predict
2953Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015263
  • Location:chr15 49528180-49702240
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb SenescentGSE19898 49701991 49702602 611 56
STAT1 HeLaGSE12782 49713517 49714729 1212 11883
STAT1 HeLaGSE12783 49713520 49714695 1175 11867
TAF HelaGSE8489 49702852 49703363 511 867
hScc1 BcellGSE12603 49702042 49702565 523 63
p130 shRbSenescentGSE19898 49702367 49702609 242 248
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 49517368 49517396 28 10799
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 49578862 49579292 430 0
ER Fulvestrant-MCF7GSE14664 49570915 49570952 37 0
FOXA1 MCF7GSE15244 49573773 49574641 868 0
FOXA1 eGFPGSE10845 49573773 49574641 868 0
Fos K562GSE19551 49679650 49680065 415 0
H3K4me3 colorectalcancer 49700958 49701870 912 0
Oct1 H2O2-HelaGSE14283 49560831 49560859 28 0
Oct1 HelaGSE14283 49570921 49570957 36 0
Oct1 HelaGSE14283 49643732 49643761 29 0
P300 T30-glioblastomaGSE21026 49573378 49573860 482 0
PHF8 293TGSE20725 49701344 49702668 1324 0
hScc1 BcellGSE12603 49578862 49579041 179 0
hScc1 BcellGSE12603 49700210 49700360 150 0
hScc1 BcellGSE12603 49701317 49701716 399 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8821 EST chr15 49537403 49538289 76 mRNA DMXL2 chr15 49528180 49702241Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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