AutismKB 2.0

Annotation Detail for VPS39


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Basic Information Top
Gene Symbol:VPS39 ( FLJ21681,FLJ46546,KIAA0770,TLP,VAM6,hVam6p )
Gene Full Name: vacuolar protein sorting 39 homolog (S. cerevisiae)
Band: 15q15.1
Quick LinksEntrez ID:23339; OMIM: 612188; Uniprot ID:VPS39_HUMAN; ENSEMBL ID: ENSG00000166887; HGNC ID: 20593
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
53Phosphoserine(MAPK)HMM predict
186Phosphotyrosine(Jak)HMM predict
242N-linkedHMM predict
339Phosphoserine(CK1)HMM predict
432N-linkedHMM predict
438Phosphoserine(IKK)HMM predict
441Phosphoserine(MAPK)HMM predict
441Phosphoserine(CDC2)HMM predict
531Phosphoserine(CDC2)HMM predict
531PhosphoserineHMM predict
646Phosphothreonine(CDK)HMM predict
646Phosphothreonine(MAPK)HMM predict
673Phosphotyrosine(Syk)HMM predict
747Phosphoserine(ATM)HMM predict
747Phosphoserine(CDC2)HMM predict
784Phosphothreonine(PKC)HMM predict
879LysineHMM predict
882AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015289
  • Location:chr15 40238191-40287793
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 40237870 40238304 434 105
Myc K562GSE19551 40237803 40238181 378 200
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 40238771 40239374 603 0
ETS1 JurkatGSE17954 40287233 40288274 1041 0
Fos K562GSE19551 40273930 40274471 541 0
GABP HelaGSE8489 40286334 40287949 1615 0
GABP k562GSE8489 40286451 40287949 1498 0
H3K4me3 colorectalcancer 40286379 40287949 1570 0
H3ac HepG2E 40285154 40287949 2795 0
Oct1 HelaGSE14283 40253365 40253396 31 0
PHF8 293TGSE20725 40287303 40288123 820 0
hScc1 BcellGSE12603 40287447 40287949 502 0
p130 shRbQuiescentGSE19898 40287244 40288254 1010 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
909 Unknown pSILAC let-7b VPS39 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000166887 n_a n_a n_a "epithelium, lymphoblast, leukocyte, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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