AutismKB 2.0

Annotation Detail for FN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FN1 ( CIG,DKFZp686F10164,DKFZp686H0342,DKFZp686I1370,DKFZp686O13149,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF )
Gene Full Name: fibronectin 1
Band: 2q35
Quick LinksEntrez ID:2335; OMIM: 135600; Uniprot ID:FINC_HUMAN; ENSEMBL ID: ENSG00000115414; HGNC ID: 3778
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
32Pyrrolidone carboxylic acid.
430N-linked (GlcNAc...).
528N-linked (GlcNAc...).
542N-linked (GlcNAc...).
876Sulfotyrosine (Potential).
877N-linked (GlcNAc...).
881Sulfotyrosine (Potential).
904Phosphoserine.
1007N-linked (GlcNAc...).
1244N-linked (GlcNAc...).
1526Cell attachment site.
2064O-linked (GalNAc...).
2065O-linked (GalNAc...).
2341Phosphoserine.
2349Phosphoserine.
2384Phosphoserine.
Location(AA) Modifications Resource
32Pyrrolidone carboxylic acid.Swiss-Prot 53.0
34Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?) (Probable).Swiss-Prot 53.0
63Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?) (Probable).Swiss-Prot 53.0
430N-linked (GlcNAc...).Swiss-Prot 53.0
528N-linked (GlcNAc...).Swiss-Prot 53.0
542N-linked (GlcNAc...).Swiss-Prot 53.0
876Sulfotyrosine (Potential).Swiss-Prot 53.0
877N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
881Sulfotyrosine (Potential).Swiss-Prot 53.0
1007N-linked (GlcNAc...).Swiss-Prot 53.0
1244N-linked (GlcNAc...).Swiss-Prot 53.0
1443Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?) (Probable).Swiss-Prot 53.0
2064O-linked (GalNAc...).Swiss-Prot 53.0
2065O-linked (GalNAc...) (By similarity).Swiss-Prot 53.0
2108N-linked (GlcNAc...) (By similarity).Swiss-Prot 53.0
2384Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
19O-linkedHMM predict
41Phosphoserine(CDC2)HMM predict
46O-linkedHMM predict
46Phosphoserine(PKG)HMM predict
46Phosphoserine(IKK)HMM predict
48Phosphoserine(IKK)HMM predict
163Phosphotyrosine(INSR)HMM predict
169S-palmitoylHMM predict
275Phosphoserine(PKA)HMM predict
279O-linkedHMM predict
283O-linkedHMM predict
345O-linkedHMM predict
430N-linkedHMM predict
528N-linkedHMM predict
542N-linkedHMM predict
604Phosphothreonine(PKC)HMM predict
607O-linkedHMM predict
607Phosphoserine(CDC2)HMM predict
621Phosphoserine(ATM)HMM predict
621Phosphoserine(IKK)HMM predict
700O-linkedHMM predict
701O-linkedHMM predict
702O-linkedHMM predict
703O-linkedHMM predict
704Phosphothreonine(CDK)HMM predict
708O-linkedHMM predict
708O-linkedHMM predict
710O-linkedHMM predict
712O-linkedHMM predict
716O-linkedHMM predict
719O-linkedHMM predict
719Phosphoserine(CDC2)HMM predict
734O-linkedHMM predict
739O-linkedHMM predict
757Phosphoserine(CK1)HMM predict
757Phosphoserine(CK2)HMM predict
757Phosphoserine(CK2)HMM predict
765Phosphotyrosine(Syk)HMM predict
765PhosphotyrosineHMM predict
765SulfotyrosineHMM predict
806Phosphoserine(ATM)HMM predict
809O-linkedHMM predict
852Phosphoserine(CK1)HMM predict
877N-linkedHMM predict
901Phosphothreonine(MAPK)HMM predict
904O-linkedHMM predict
906Phosphothreonine(PKC)HMM predict
909Phosphoserine(CDC2)HMM predict
968Phosphoserine(CDC2)HMM predict
1007N-linkedHMM predict
1090O-linkedHMM predict
1132Phosphothreonine(PKA)HMM predict
1144Phosphothreonine(MAPK)HMM predict
1149Phosphotyrosine(Jak)HMM predict
1172Phosphothreonine(CDK)HMM predict
1175Phosphoserine(CDC2)HMM predict
1303Phosphoserine(CDC2)HMM predict
1317Phosphoserine(CDC2)HMM predict
1317Phosphoserine(ATM)HMM predict
1334Phosphotyrosine(Jak)HMM predict
1340Phosphoserine(CK1)HMM predict
1342Phosphotyrosine(EGFR)HMM predict
1348Phosphothreonine(CDK)HMM predict
1360Phosphoserine(CDC2)HMM predict
1417N-linkedHMM predict
1419Phosphothreonine(MAPK)HMM predict
1424Phosphotyrosine(Jak)HMM predict
1460Phosphothreonine(MAPK)HMM predict
1474Phosphothreonine(PKC)HMM predict
1527Phosphoserine(IKK)HMM predict
1530Phosphoserine(CK2)HMM predict
1531Phosphoserine(CK1)HMM predict
1565O-linkedHMM predict
1567Phosphoserine(CDC2)HMM predict
1572Phosphotyrosine(Jak)HMM predict
1575O-linkedHMM predict
1577Phosphothreonine(CDC2)HMM predict
1589O-linkedHMM predict
1608Phosphotyrosine(Jak)HMM predict
1616N-linkedHMM predict
1665Phosphothreonine(PKC)HMM predict
1666Phosphotyrosine(INSR)HMM predict
1711Phosphoserine(ATM)HMM predict
1720O-linkedHMM predict
1734O-linkedHMM predict
1734Phosphothreonine(MAPK)HMM predict
1737Phosphoserine(MAPK)HMM predict
1739O-linkedHMM predict
1743Phosphothreonine(MAPK)HMM predict
1757Phosphothreonine(MAPK)HMM predict
1774O-linkedHMM predict
1775O-linkedHMM predict
1776Phosphoserine(CK1)HMM predict
1813N-linkedHMM predict
1823Phosphothreonine(PKA)HMM predict
1855Phosphothreonine(MAPK)HMM predict
1893Phosphoserine(CDC2)HMM predict
1942Phosphoserine(CDC2)HMM predict
1942PhosphoserineHMM predict
1991Phosphothreonine(PKA)HMM predict
2040O-linkedHMM predict
2061Phosphothreonine(PKA)HMM predict
2064O-linkedHMM predict
2067Phosphothreonine(CDC2)HMM predict
2067Phosphothreonine(MAPK)HMM predict
2096SulfotyrosineHMM predict
2117Phosphoserine(CK1)HMM predict
2117Phosphoserine(ATM)HMM predict
2154O-linkedHMM predict
2155O-linkedHMM predict
2156O-linkedHMM predict
2156O-linkedHMM predict
2158O-linkedHMM predict
2278S-palmitoylHMM predict
2302Phosphotyrosine(INSR)HMM predict
2341O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_002026
  • Location:chr2 215933425-216009035
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 215983640 215984590 950 0
Fos K562GSE19551 215983753 215984237 484 0
FoxA1 MCF7MACSdata 215934792 215935004 212 0
FoxA1 MCF7MACSdata 215970665 215970916 251 0
Nanog hESGSE18292 215970975 215971447 472 0
P300 T0-glioblastomaGSE21026 215983626 215984701 1075 0
P300 T30-glioblastomaGSE21026 215969451 215970124 673 0
P300 T30-glioblastomaGSE21026 215983675 215984585 910 0
RARA MCF7GSE15244 215934783 215935349 566 0
Stat6 IL-4-hr4GSE17850 215967312 215967816 504 0
TFAP2C MCF7GSE21234 215934850 215935237 387 0
p130 SenescentGSE19898 215985094 215985383 289 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-200c hsa-mir-200c 12 19435871
hsa-miR-200c* hsa-mir-200c 12 19435871
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15612 mRNA chr2 216050137 216051857 1169 mRNA FN1 chr2 216050686 216126297Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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