AutismKB 2.0

Annotation Detail for CRTC1


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Basic Information Top
Gene Symbol:CRTC1 ( FLJ14027,KIAA0616,MECT1,TORC1,WAMTP1 )
Gene Full Name: CREB regulated transcription coactivator 1
Band: 19p13.11
Quick LinksEntrez ID:23373; OMIM: 607536; Uniprot ID:CRTC1_HUMAN; ENSEMBL ID: ENSG00000105662; HGNC ID: 16062
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
64Phosphoserine (By similarity).
86Phosphoserine (By similarity).
139Phosphoserine (By similarity).
149Phosphothreonine (By similarity).
151Phosphoserine; by SNF1lK2.
161Phosphothreonine.
172Phosphoserine.
258Nuclear export signal (By similarity).
277Phosphoserine (By similarity).
440Phosphoserine (By similarity).
Location(AA) Modifications Resource
167Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
133Phosphotyrosine(Syk)HMM predict
139Phosphoserine(ATM)HMM predict
151PhosphoserineHMM predict
161Phosphothreonine(CDK)HMM predict
167Phosphoserine(IKK)HMM predict
169Phosphoserine(CK1)HMM predict
170Phosphoserine(CDK)HMM predict
172Phosphoserine(ATM)HMM predict
191Phosphothreonine(CK2)HMM predict
193Phosphoserine(CK2)HMM predict
198N-linkedHMM predict
211Phosphoserine(PKA)HMM predict
211PhosphoserineHMM predict
215Phosphoserine(IKK)HMM predict
231N-linkedHMM predict
273O-linkedHMM predict
275Phosphoserine(CK1)HMM predict
276Phosphoserine(CK1)HMM predict
284N-linkedHMM predict
298O-linkedHMM predict
298Phosphoserine(IKK)HMM predict
299Phosphothreonine(MAPK)HMM predict
302O-linkedHMM predict
326Phosphoserine(IKK)HMM predict
330Phosphoserine(ATM)HMM predict
330Phosphoserine(CDK)HMM predict
330Phosphoserine(CDC2)HMM predict
333O-linkedHMM predict
345Phosphoserine(CK1)HMM predict
360Phosphoserine(ATM)HMM predict
377Phosphoserine(ATM)HMM predict
377O-linkedHMM predict
416O-linkedHMM predict
420Phosphoserine(IKK)HMM predict
420O-linkedHMM predict
424Phosphoserine(ATM)HMM predict
424Phosphoserine(CDC2)HMM predict
424Phosphoserine(IKK)HMM predict
453Phosphoserine(IKK)HMM predict
453Phosphoserine(CDC2)HMM predict
456N-linkedHMM predict
458Phosphoserine(CDC2)HMM predict
458Phosphoserine(IKK)HMM predict
461Phosphoserine(CDC2)HMM predict
461Phosphoserine(MAPK)HMM predict
461Phosphoserine(IKK)HMM predict
469O-linkedHMM predict
469Phosphoserine(CDC2)HMM predict
472O-linkedHMM predict
473Phosphoserine(CDC2)HMM predict
473Phosphoserine(ATM)HMM predict
477O-linkedHMM predict
489SulfotyrosineHMM predict
489Phosphotyrosine(Syk)HMM predict
516Phosphoserine(CK1)HMM predict
521Phosphotyrosine(INSR)HMM predict
522Phosphoserine(IKK)HMM predict
530Phosphoserine(ATM)HMM predict
547Phosphoserine(ATM)HMM predict
578Phosphothreonine(CK2)HMM predict
593Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015321
  • Location:chr19 18655503-18749756
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 18677830 18678413 583 0
CTCF G2GSE9613 18731855 18732002 147 0
CTCF G2GSE9613 18743125 18743733 608 0
CTCF G2GSE9613 18744447 18744826 379 0
ER Breast-CancerGSE22609 18741831 18742222 391 0
ER E2-MCF7GSE14664 18708844 18708936 92 0
ER E2-MCF7GSE14664 18723864 18723905 41 0
ER MCF7GSE19013 18740996 18741772 776 0
ER MCF7GSE19013 18741850 18742403 553 0
FOXA1 MCF7GSE15244 18668807 18669138 331 0
FOXA1 MCF7GSE15244 18728558 18729051 493 0
Fos K562GSE19551 18672638 18673210 572 0
Fos K562GSE19551 18735789 18736356 567 0
Gata1 K562GSE18868 18714784 18715697 913 0
Gata2 K562GSE18868 18672334 18673213 879 0
Myc K562GSE19551 18659731 18660325 594 0
Myc K562GSE19551 18714917 18715466 549 0
Oct1 H2O2-HelaGSE14283 18723871 18723901 30 0
Oct1 H2O2-HelaGSE14283 18735983 18736011 28 0
Oct1 H2O2-HelaGSE14283 18748231 18748261 30 0
Oct1 HelaGSE14283 18678575 18678606 31 0
Oct1 HelaGSE14283 18723872 18723907 35 0
Oct1 HelaGSE14283 18736326 18736362 36 0
Oct1 HelaGSE14283 18748228 18748260 32 0
Oct4 hESGSE17917 18655371 18655728 357 0
P300 T0-glioblastomaGSE21026 18705002 18705520 518 0
PHF8 293TGSE20725 18654971 18656123 1152 0
RARA MCF7GSE15244 18669555 18670928 1373 0
RARA MCF7GSE15244 18728454 18729378 924 0
RARA MCF7GSE15244 18735491 18737212 1721 0
TFAP2C MCF7GSE21234 18668707 18669090 383 0
TFAP2C MCF7GSE21234 18703318 18703737 419 0
TFAP2C MCF7GSE21234 18722083 18722859 776 0
TFAP2C MCF7GSE21234 18728633 18729167 534 0
TFAP2C MCF7GSE21234 18734295 18734883 588 0
TFAP2C MCF7GSE21234 18735512 18736684 1172 0
TFAP2C MCF7GSE21234 18740935 18741747 812 0
hScc1 BcellGSE12603 18668994 18669138 144 0
hScc1 BcellGSE12603 18697224 18698249 1025 0
hScc1 BcellGSE12603 18701990 18702447 457 0
hScc1 BcellGSE12603 18703377 18703632 255 0
hScc1 BcellGSE12603 18713540 18713796 256 0
hScc1 BcellGSE12603 18718125 18718884 759 0
hScc1 BcellGSE12603 18731666 18732038 372 0
hScc1 BcellGSE12603 18733852 18734149 297 0
hScc1 BcellGSE12603 18737269 18737445 176 0
hScc1 BcellGSE12603 18743257 18743641 384 0
hScc1 BcellGSE12603 18748976 18749486 510 0
p130 SenescentGSE19898 18655483 18655690 207 0
p130 shRbSenescentGSE19898 18655438 18655671 233 0
p63 keratinocytesGSE17611 18735442 18736813 1371 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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