AutismKB 2.0

Annotation Detail for HARS2


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Basic Information Top
Gene Symbol:HARS2 ( HARSL,HARSR,HO3 )
Gene Full Name: histidyl-tRNA synthetase 2, mitochondrial (putative)
Band: 5q31.3
Quick LinksEntrez ID:23438; OMIM: 600783; Uniprot ID:SYHM_HUMAN; ENSEMBL ID: ENSG00000112855; HGNC ID: 4817
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
67Phosphoserine.
444N6-acetyllysine.
Location(AA) Modifications Resource
67Phosphoserine.Swiss-Prot 53.0
67PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
24S-palmitoylHMM predict
67Phosphoserine(ATM)HMM predict
344Phosphothreonine(MAPK)HMM predict
400Phosphothreonine(PKC)HMM predict
504SerineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012208
  • Location:chr5 140051201-140059072
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 140050561 140051802 1241 20
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 140052018 140052331 313 0
GABP k562GSE8489 140054857 140055772 915 0
H3K4me3 colorectalcancer 140052018 140052331 313 0
PHF8 HeLaGSE20725 140050668 140051850 1182 0
TAF HelaGSE8489 140055343 140056117 774 0
TAFII hESGSE17917 140050805 140051618 813 0
p130 shRbSenescentGSE19898 140050780 140051699 919 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018