AutismKB 2.0

Annotation Detail for NPTXR


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Basic Information Top
Gene Symbol:NPTXR ( NPR )
Gene Full Name: neuronal pentraxin receptor
Band: 22q13.1
Quick LinksEntrez ID:23467; OMIM: 609474; Uniprot ID:NPTXR_HUMAN; ENSEMBL ID: ENSG00000221890; HGNC ID: 7954
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
42N-linked (GlcNAc...) (Potential).
216N-linked (GlcNAc...) (Potential).
463N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
42N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
215N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
462N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
31Phosphoserine(CDK)HMM predict
31PhosphoserineHMM predict
31Phosphoserine(CDC2)HMM predict
47O-linkedHMM predict
52Phosphoserine(MAPK)HMM predict
52O-linkedHMM predict
81O-linkedHMM predict
105Phosphoserine(IKK)HMM predict
178Phosphothreonine(PKA)HMM predict
217O-linkedHMM predict
224O-linkedHMM predict
287Phosphotyrosine(INSR)HMM predict
287Phosphotyrosine(SRC)HMM predict
287Phosphotyrosine(Syk)HMM predict
329Phosphoserine(IKK)HMM predict
329Phosphoserine(CK1)HMM predict
335O-linkedHMM predict
403Phosphoserine(CK2)HMM predict
453Phosphothreonine(MAPK)HMM predict
462N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014293
  • Location:chr22 37544403-37569962
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 37572878 37573270 392 3112
H3K27me3 colorectalcancer 37572548 37573139 591 2881
H3K27me3 colorectalcancer 37575103 37575615 512 5397
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF mAbJurkat 37537622 37538123 501 6531
NRSF mAbJurkat 37539164 37539722 558 4961
NRSF mAbJurkat 37540555 37541452 897 3400
NRSF mAbJurkat 37542415 37542909 494 1742
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 37569326 37569590 264 0
CTCF CD4SISSRdata 37569326 37569590 264 0
CTCF G2GSE9613 37550622 37551116 494 0
CTCF G2GSE9613 37569125 37569501 376 0
NRSF JurkatGSE13047 37550158 37551903 1745 0
NRSF mAbJurkat 37545682 37546615 933 0
NRSF mAbJurkat 37548847 37549534 687 0
NRSF mAbJurkat 37550259 37551150 891 0
NRSF mAbJurkat 37552336 37553165 829 0
NRSF mAbJurkat 37554063 37555771 1708 0
NRSF-mono JurkatQuESTdata 37550170 37551447 1277 0
NRSF-poly JurkatQuESTdata 37550158 37551483 1325 0
P300 T30-glioblastomaGSE21026 37561561 37562508 947 0
hScc1 BcellGSE12603 37567101 37567434 333 0
hScc1 BcellGSE12603 37569125 37569501 376 0
hScc1 CdLSGSE12603 37569125 37569501 376 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018