Annotation Detail for TRAM1

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Basic Information Top

Gene Symbol:	TRAM1 ( PNAS8,PRO1292,TRAM,TRAMP )
Gene Full Name:	translocation associated membrane protein 1
Band:	8q13.3
Quick Links	Entrez ID:23471; OMIM: 605190; Uniprot ID:TRAM1_HUMAN; ENSEMBL ID: ENSG00000067167; HGNC ID: 20568
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
56	N-linked (GlcNAc...) (Probable).
365	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	71683089	71683478	389	126
CTCF	CD4	SISSRdata	71683089	71683478	389	126
CTCF	G2	GSE9613	71682922	71683562	640	85
CTCF	G2	GSE9613	71689572	71690177	605	6717
FoxA1	MCF7	MACSdata	71687034	71687162	128	3941
H3ac	HepG2	E	71683791	71684581	790	1029
hScc1	CdLS	GSE12603	71682851	71683598	747	67
hScc1	G2	GSE9613	71683032	71683562	530	140
p130	shRbSenescent	GSE19898	71683268	71683597	329	275
p63	keratinocytes	GSE17611	71684715	71685587	872	1994

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	E2-MCF7	GSE14664	71641317	71641370	53	6883
Oct1	Hela	GSE14283	71647302	71647336	34	908

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
ETS1	Jurkat	GSE17954	71682602	71683603	1001
H3K4me2	HCT116	GSE10453	71681843	71682179	336
H3K4me3	colorectal	cancer	71681775	71682179	404
H3ac	HepG2	E	71681742	71682217	475
TFAP2C	MCF7	GSE21234	71682854	71683285	431
hScc1	Bcell	GSE12603	71682642	71683348	706

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7b	hsa-let-7b	22	18668040
hsa-let-7b*	hsa-let-7b	22	18668040
hsa-miR-1	hsa-mir-1-2	18	18668040
hsa-miR-1	hsa-mir-1-1	20	18668040
hsa-miR-155	hsa-mir-155	21	18668040
hsa-miR-155*	hsa-mir-155	21	18668040
hsa-miR-16	hsa-mir-16-1	13	18668040
hsa-miR-16	hsa-mir-16-2	3	18668040
hsa-miR-30a	hsa-mir-30a	6	18668040
hsa-miR-30a*	hsa-mir-30a	6	18668040
hsa-miR-30b	hsa-mir-30b	8	18668040
hsa-miR-30b*	hsa-mir-30b	8	18668040
hsa-miR-30c	hsa-mir-30c-2	6	18668040
hsa-miR-30c	hsa-mir-30c-1	1	18668040
hsa-miR-30c-1*	hsa-mir-30c-1	1	18668040
hsa-miR-30c-2*	hsa-mir-30c-2	6	18668040
hsa-miR-30d	hsa-mir-30d	8	18668040
hsa-miR-30d*	hsa-mir-30d	8	18668040
hsa-miR-30e	hsa-mir-30e	1	18668040
hsa-miR-30e*	hsa-mir-30e	1	18668040

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
1013	Unknown	pSILAC	miR-155	TRAM1	down 75-50%	18668040
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000067167		n_a	n_a	n_a	"epithelium, squamous cell, lymphoblast, lymphocyte, leukocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018