AutismKB 2.0

Annotation Detail for BRD4


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Basic Information Top
Gene Symbol:BRD4 ( CAP,HUNK1,HUNKI,MCAP )
Gene Full Name: bromodomain containing 4
Band: 19p13.12
Quick LinksEntrez ID:23476; OMIM: 608749; Uniprot ID:BRD4_HUMAN; ENSEMBL ID: ENSG00000141867; HGNC ID: 13575
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
469Phosphoserine.
470Phosphoserine.
598Phosphothreonine (By similarity).
601Phosphoserine.
1045Phosphoserine.
1111N6-acetyllysine.
1117Phosphoserine.
Location(AA) Modifications Resource
470Phosphoserine.Swiss-Prot 53.0
470PhosphoserinePhospho.ELM 6.0
1045Phosphoserine.Swiss-Prot 53.0
1117Phosphoserine.Swiss-Prot 53.0
1117PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
5Phosphoserine(IKK)HMM predict
24Phosphoserine(ATM)HMM predict
42O-linkedHMM predict
43O-linkedHMM predict
60Phosphothreonine(PKA)HMM predict
97Phosphotyrosine(INSR)HMM predict
118SulfotyrosineHMM predict
181MethylarginineHMM predict
186Phosphothreonine(PKC)HMM predict
186Phosphothreonine(PKA)HMM predict
194O-linkedHMM predict
198N-linkedHMM predict
200O-linkedHMM predict
200O-linkedHMM predict
203O-linkedHMM predict
204Phosphothreonine(CDK)HMM predict
204Phosphothreonine(MAPK)HMM predict
208O-linkedHMM predict
210O-linkedHMM predict
210Phosphothreonine(CDK)HMM predict
210Phosphothreonine(MAPK)HMM predict
210Phosphothreonine(CDC2)HMM predict
221Phosphothreonine(MAPK)HMM predict
221O-linkedHMM predict
221O-linkedHMM predict
249O-linkedHMM predict
249Phosphothreonine(MAPK)HMM predict
249O-linkedHMM predict
294O-linkedHMM predict
298O-linkedHMM predict
299O-linkedHMM predict
308O-linkedHMM predict
324Phosphoserine(PKG)HMM predict
325Phosphoserine(PKA)HMM predict
338Phosphoserine(ATM)HMM predict
390Phosphotyrosine(INSR)HMM predict
469O-linkedHMM predict
469O-linkedHMM predict
470O-linkedHMM predict
470Phosphoserine(CDC2)HMM predict
484O-linkedHMM predict
485O-linkedHMM predict
486O-linkedHMM predict
494Phosphoserine(CK1)HMM predict
494Phosphoserine(ATM)HMM predict
498Phosphoserine(IKK)HMM predict
498Phosphoserine(CK1)HMM predict
499Phosphoserine(CK1)HMM predict
529Phosphoserine(ATM)HMM predict
577N-linkedHMM predict
580N-linkedHMM predict
582N-linkedHMM predict
593O-linkedHMM predict
599Phosphotyrosine(SRC)HMM predict
601Phosphoserine(CK2)HMM predict
643Phosphoserine(CK1)HMM predict
706Phosphoserine(CK1)HMM predict
712Phosphoserine(ATM)HMM predict
712Phosphoserine(CK1)HMM predict
717Phosphoserine(CK1)HMM predict
796Phosphoserine(ATM)HMM predict
846O-linkedHMM predict
847Phosphothreonine(MAPK)HMM predict
847Phosphothreonine(CDK)HMM predict
891O-linkedHMM predict
891O-linkedHMM predict
942Phosphothreonine(MAPK)HMM predict
1064Phosphoserine(CDC2)HMM predict
1078Phosphoserine(IKK)HMM predict
1126Phosphoserine(CDC2)HMM predict
1128O-linkedHMM predict
1212Phosphothreonine(MAPK)HMM predict
1212Phosphothreonine(CDK)HMM predict
1215O-linkedHMM predict
1216O-linkedHMM predict
1262PhosphoserineHMM predict
1309Phosphothreonine(MAPK)HMM predict
1315Phosphoserine(ATM)HMM predict
1315Phosphoserine(IKK)HMM predict
1319Phosphoserine(IKK)HMM predict
1355Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014299
  • Location:chr19 15218848-15252261
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 15268713 15269771 1058 16981
H3ac HepG2E 15270539 15271126 587 18571
USF2 HepG2E 15268713 15269410 697 16800
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 15235932 15236153 221 0
CTCF CD4SISSRdata 15235932 15236153 221 0
CTCF G2GSE9613 15224074 15224592 518 0
CTCF G2GSE9613 15225257 15225636 379 0
CTCF G2GSE9613 15235546 15236608 1062 0
Rb GrowingGSE19898 15223599 15223887 288 0
Rb GrowingGSE19898 15235922 15236166 244 0
Rb GrowingGSE19898 15237498 15238102 604 0
Rb QuiescentGSE19898 15223645 15224405 760 0
Rb QuiescentGSE19898 15237357 15238006 649 0
Rb SenescentGSE19898 15220800 15221148 348 0
Rb SenescentGSE19898 15223549 15224055 506 0
Rb SenescentGSE19898 15235940 15236272 332 0
Rb SenescentGSE19898 15237292 15238172 880 0
Rb shRbQuiescentGSE19898 15223733 15224020 287 0
Rb shRbSenescenceGSE19898 15223718 15223906 188 0
Rb shRbSenescenceGSE19898 15237578 15237918 340 0
TFAP2C MCF7GSE21234 15220719 15221308 589 0
TFAP2C MCF7GSE21234 15221870 15222569 699 0
hScc1 BcellGSE12603 15224946 15225366 420 0
hScc1 BcellGSE12603 15235854 15236793 939 0
hScc1 CdLSGSE12603 15235818 15236497 679 0
p130 QuiescentGSE19898 15223720 15224056 336 0
p130 QuiescentGSE19898 15237490 15237925 435 0
p130 SenescentGSE19898 15220690 15221187 497 0
p130 SenescentGSE19898 15223656 15224113 457 0
p130 SenescentGSE19898 15237489 15238182 693 0
p130 shRbQuiescentGSE19898 15223442 15224054 612 0
p130 shRbSenescentGSE19898 15223501 15224115 614 0
p130 shRbSenescentGSE19898 15235880 15236410 530 0
p130 shRbSenescentGSE19898 15237414 15238107 693 0
p63 keratinocytesGSE17611 15248084 15249117 1033 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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