AutismKB 2.0

Annotation Detail for SUZ12


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Basic Information Top
Gene Symbol:SUZ12 ( CHET9,JJAZ1,KIAA0160 )
Gene Full Name: suppressor of zeste 12 homolog (Drosophila)
Band: 17q11.2
Quick LinksEntrez ID:23512; OMIM: 606245; Uniprot ID:SUZ12_HUMAN; ENSEMBL ID: ENSG00000178691; HGNC ID: 17101
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
418Phosphothreonine.
546Phosphoserine.
583Phosphoserine.
726Phosphoserine.
Location(AA) Modifications Resource
546Phosphoserine.Swiss-Prot 53.0
546PhosphoserinePhospho.ELM 6.0
546PhosphoserinePhospho.ELM 6.0
583PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
14O-linkedHMM predict
17O-linkedHMM predict
37O-linkedHMM predict
53O-linkedHMM predict
53Phosphoserine(IKK)HMM predict
152Phosphoserine(CK1)HMM predict
175Phosphoserine(IKK)HMM predict
192S-palmitoylHMM predict
220N-linkedHMM predict
226N-linkedHMM predict
315Phosphotyrosine(Syk)HMM predict
350Phosphoserine(ATM)HMM predict
350O-linkedHMM predict
397O-linkedHMM predict
405Phosphoserine(PKG)HMM predict
412Phosphothreonine(PKC)HMM predict
436N-linkedHMM predict
437N-linkedHMM predict
442Phosphothreonine(PKC)HMM predict
523Phosphothreonine(CDC2)HMM predict
539Phosphoserine(PKG)HMM predict
546Phosphoserine(CK2)HMM predict
690O-linkedHMM predict
695Phosphoserine(CDC2)HMM predict
702Phosphothreonine(CK2)HMM predict
706N-linkedHMM predict
710N-linkedHMM predict
717Phosphoserine(CK1)HMM predict
726Phosphoserine(CK1)HMM predict
731Phosphoserine(CDK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015355
  • Location:chr17 27288184-27352161
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 27287734 27287913 179 361
LIN9 G0GSE7516 27287734 27288177 443 229
LIN9 SGSE7516 27287734 27288056 322 290
Oct1 HelaGSE14283 27273404 27273434 30 14766
PolII HeLaGSE12783 27287008 27288781 1773 290
USF1 HepG2E 27287734 27287950 216 343
p130 SenescentGSE19898 27287755 27287944 189 335
p130 shRbSenescentGSE19898 27287781 27287946 165 321
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 27358262 27358569 307 6254
CTCF CD4SISSRdata 27358262 27358569 307 6254
CTCF G2GSE9613 27358148 27358842 694 6334
H3ac HepG2E 27359221 27359919 698 7409
Oct1 HelaGSE14283 27361924 27361991 67 9796
USF1 HepG2E 27357586 27358174 588 5719
hScc1 BcellGSE12603 27358101 27358881 780 6330
hScc1 CdLSGSE12603 27358252 27358881 629 6405
hScc1 G2GSE9613 27357586 27358842 1256 6053
p130 QuiescentGSE19898 27357729 27358047 318 5727
p130 SenescentGSE19898 27357633 27358045 412 5678
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 27288833 27289460 627 0
H3K4me3 colorectalcancer 27288637 27289349 712 0
H3ac HepG2E 27288571 27290121 1550 0
KLF4 hESGSE17917 27300777 27300937 160 0
Oct1 HelaGSE14283 27305587 27305618 31 0
Oct4 hESGSE17917 27300780 27300931 151 0
TAF HelaGSE8489 27288761 27289387 626 0
TAF k562GSE8489 27288670 27290599 1929 0
USF1 HepG2E 27288907 27289568 661 0
hScc1 CdLSGSE12603 27287989 27288670 681 0
p130 SenescentGSE19898 27288190 27288381 191 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-200b hsa-mir-200b 1 20832727
hsa-miR-200b* hsa-mir-200b 1 20832727
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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