AutismKB 2.0

Annotation Detail for SCRIB


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Basic Information Top
Gene Symbol:SCRIB ( CRIB1,SCRB1,SCRIB1,Vartul )
Gene Full Name: scribbled homolog (Drosophila)
Band: 8q24.3
Quick LinksEntrez ID:23513; OMIM: 607733; Uniprot ID:SCRIB_HUMAN; ENSEMBL ID: ENSG00000180900; HGNC ID: 30377
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
35Phosphoserine.
487Phosphoserine.
504Phosphoserine.
689Phosphothreonine (By similarity).
749Phosphothreonine.
826Phosphothreonine.
834Phosphotyrosine.
835Phosphoserine.
853Phosphoserine.
875Phosphoserine.
939Phosphoserine.
941Phosphothreonine.
1140Phosphoserine.
1220Phosphoserine.
1223Phosphoserine.
1225Phosphoserine.
1226Phosphoserine.
1232Phosphoserine.
1298Phosphoserine.
1300Phosphoserine.
1306Phosphoserine.
1309Phosphoserine.
1342Phosphothreonine.
1348Phosphoserine.
1360Phosphotyrosine.
1378Phosphoserine.
1437Phosphoserine.
1439Phosphoserine.
1448Phosphoserine.
1475Phosphoserine.
1486Phosphoserine.
1508Phosphoserine.
1547Phosphoserine.
1561Phosphoserine.
1566Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_182706
  • Location:chr8 144945077-144969536
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 144969376 144970558 1182 431
hScc1 BcellGSE12603 144969305 144970558 1253 395
hScc1 CdLSGSE12603 144969705 144970267 562 450
p130 shRbSenescentGSE19898 144969409 144969682 273 9
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 144940881 144941488 607 3893
TFAP2C MCF7GSE21234 144925703 144925995 292 19229
hScc1 BcellGSE12603 144925897 144926475 578 18892
hScc1 BcellGSE12603 144926920 144927156 236 18040
hScc1 BcellGSE12603 144942543 144943048 505 2282
hScc1 CdLSGSE12603 144925777 144926270 493 19054
hScc1 G2GSE9613 144940881 144941522 641 3876
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 144952507 144952675 168 0
CTCF CD4SISSRdata 144952507 144952675 168 0
FOXA1 MCF7GSE15244 144950402 144950929 527 0
GATA3 MCF7GSE15244 144955049 144955365 316 0
H3ac HepG2E 144968382 144969140 758 0
NRSF pAbJurkat 144945214 144946070 856 0
NRSF pAbJurkat 144946667 144947201 534 0
NRSF pAbJurkat 144955742 144955926 184 0
NRSF pAbJurkat 144958671 144960884 2213 0
NRSF pAbJurkat 144964181 144964774 593 0
NRSF pAbJurkat 144965282 144965954 672 0
NRSF pAbJurkat 144966303 144967103 800 0
TFAP2C MCF7GSE21234 144966809 144968064 1255 0
TFAP2C MCF7GSE21234 144968361 144969368 1007 0
hScc1 BcellGSE12603 144957437 144957634 197 0
hScc1 BcellGSE12603 144962379 144964929 2550 0
hScc1 BcellGSE12603 144965860 144967588 1728 0
hScc1 CdLSGSE12603 144968326 144968991 665 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018