AutismKB 2.0

Annotation Detail for FOSB


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Basic Information Top
Gene Symbol:FOSB ( AP-1,DKFZp686C0818,G0S3,GOS3,GOSB,MGC42291 )
Gene Full Name: FBJ murine osteosarcoma viral oncogene homolog B
Band: 19q13.32
Quick LinksEntrez ID:2354; OMIM: 164772; Uniprot ID:FOSB_HUMAN; ENSEMBL ID: ENSG00000125740; HGNC ID: 3797
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
17Phosphoserine(CK1)HMM predict
18Phosphoserine(MAPK)HMM predict
18Phosphoserine(CDC2)HMM predict
18PhosphoserineHMM predict
20Phosphoserine(CK1)HMM predict
28Phosphoserine(ATM)HMM predict
31O-linkedHMM predict
34O-linkedHMM predict
34Phosphoserine(CDC2)HMM predict
37O-linkedHMM predict
37O-linkedHMM predict
57O-linkedHMM predict
82Phosphoserine(ATM)HMM predict
89Phosphoserine(ATM)HMM predict
105Phosphoserine(IKK)HMM predict
105O-linkedHMM predict
114Phosphoserine(ATM)HMM predict
120Phosphoserine(ATM)HMM predict
120O-linkedHMM predict
124O-linkedHMM predict
125O-linkedHMM predict
126O-linkedHMM predict
128O-linkedHMM predict
129O-linkedHMM predict
129O-linkedHMM predict
130O-linkedHMM predict
130Phosphoserine(IKK)HMM predict
151Phosphothreonine(CK2)HMM predict
151Phosphothreonine(MAPK)HMM predict
180Phosphothreonine(PKA)HMM predict
275N-linkedHMM predict
297N-linkedHMM predict
302O-linkedHMM predict
321Phosphoserine(IKK)HMM predict
323O-linkedHMM predict
332Phosphoserine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006732
  • Location:chr19 50663092-50670275
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP GMOGSE8489 50659888 50660257 369 3020
KLF4 hESGSE17917 50645976 50646215 239 16997
P300 T30-glioblastomaGSE21026 50650232 50651901 1669 12026
Rb GrowingGSE19898 50646224 50646417 193 16772
Rb GrowingGSE19898 50650872 50651080 208 12117
Rb shRbQuiescentGSE19898 50646460 50646678 218 16524
SRF GMOGSE8489 50654194 50654573 379 8709
SRF GMOGSE8489 50659888 50660714 826 2792
SRF HepG2GSE8489 50659888 50660257 369 3020
SRF k562GSE8489 50662154 50663309 1155 361
TAF HelaGSE8489 50645275 50645560 285 17675
TAF k562GSE8489 50645275 50645560 285 17675
USF1 HepG2E 50643889 50644434 545 18931
p130 QuiescentGSE19898 50645267 50645794 527 17562
p130 QuiescentGSE19898 50646099 50646928 829 16579
p130 QuiescentGSE19898 50651093 50651398 305 11847
p130 QuiescentGSE19898 50662419 50663231 812 268
p130 SenescentGSE19898 50645352 50645748 396 17543
p130 SenescentGSE19898 50646106 50646929 823 16575
p130 SenescentGSE19898 50650866 50651305 439 12007
p130 shRbQuiescentGSE19898 50645141 50645976 835 17534
p130 shRbQuiescentGSE19898 50646123 50647009 886 16527
p130 shRbQuiescentGSE19898 50651072 50651656 584 11729
p130 shRbQuiescentGSE19898 50662145 50663521 1376 260
p130 shRbSenescentGSE19898 50645202 50645643 441 17670
p130 shRbSenescentGSE19898 50645651 50645932 281 17301
p130 shRbSenescentGSE19898 50646014 50647109 1095 16531
p130 shRbSenescentGSE19898 50650931 50651534 603 11860
p130 shRbSenescentGSE19898 50662159 50662654 495 686
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 50673534 50674645 1111 3814
FOXA1 MCF7GSE15244 50673534 50674205 671 3594
LIN9 SGSE7516 50673473 50674141 668 3532
Rb SenescentGSE19898 50673118 50673378 260 2973
Rb SenescentGSE19898 50673594 50673970 376 3507
Rb SenescentGSE19898 50674063 50674465 402 3989
hScc1 BcellGSE12603 50673437 50674747 1310 3817
hScc1 CdLSGSE12603 50673300 50674747 1447 3748
hScc1 G2GSE9613 50673437 50674645 1208 3766
p130 QuiescentGSE19898 50673650 50673995 345 3547
p130 SenescentGSE19898 50673538 50674139 601 3563
p130 shRbSenescentGSE19898 50673645 50674123 478 3609
p130 shRbSenescentGSE19898 50674168 50674366 198 3992
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 50663885 50665258 1373 0
Rb GrowingGSE19898 50663862 50664028 166 0
Rb SenescentGSE19898 50663980 50664642 662 0
hScc1 BcellGSE12603 50664244 50664883 639 0
hScc1 BcellGSE12603 50667671 50668200 529 0
p130 QuiescentGSE19898 50663895 50664528 633 0
p130 QuiescentGSE19898 50664578 50664923 345 0
p130 SenescentGSE19898 50663979 50665055 1076 0
p130 SenescentGSE19898 50668023 50668416 393 0
p130 shRbQuiescentGSE19898 50663816 50665387 1571 0
p130 shRbSenescentGSE19898 50664493 50665142 649 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-101 hsa-mir-101-1 1 19133651
hsa-miR-101 hsa-mir-101-2 9 19133651
hsa-miR-101* hsa-mir-101-1 1 19133651
hsa-miR-155 hsa-mir-155 21 18048365
hsa-miR-155* hsa-mir-155 21 18048365
hsa-miR-205 hsa-mir-205 1 20065103
hsa-miR-224 hsa-mir-224 X 20065103
hsa-miR-335 hsa-mir-335 7 20065103
hsa-miR-335* hsa-mir-335 7 20065103
hsa-miR-424 hsa-mir-424 X 20065103
hsa-miR-424* hsa-mir-424 X 20065103
hsa-miR-451 hsa-mir-451 17 20065103
hsa-miR-491-3p hsa-mir-491 9 20065103
hsa-miR-491-5p hsa-mir-491 9 20065103
hsa-miR-93 hsa-mir-93 7 20065103
hsa-miR-93* hsa-mir-93 7 20065103
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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