AutismKB 2.0

Annotation Detail for GTPBP4


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Basic Information Top
Gene Symbol:GTPBP4 ( CRFG,FLJ10686,FLJ10690,FLJ39774,NGB,NOG1 )
Gene Full Name: GTP binding protein 4
Band: 10p15.3
Quick LinksEntrez ID:23560; OMIM: NA; Uniprot ID:NOG1_HUMAN; ENSEMBL ID: ENSG00000107937; HGNC ID: 21535
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
103N6-acetyllysine.
468Phosphoserine.
470Phosphoserine.
472Phosphoserine.
522N6-acetyllysine.
558Phosphoserine.
563Phosphoserine.
578Phosphoserine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
467PhosphoserinePhospho.ELM 6.0
468Phosphoserine.Swiss-Prot 53.0
469PhosphoserinePhospho.ELM 6.0
470Phosphoserine.Swiss-Prot 53.0
471PhosphoserinePhospho.ELM 6.0
472Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
201Phosphothreonine(PKC)HMM predict
300Phosphoserine(CK2)HMM predict
346Phosphothreonine(PKC)HMM predict
409SulfotyrosineHMM predict
468Phosphoserine(ATM)HMM predict
472Phosphoserine(CK2)HMM predict
550Phosphothreonine(PKC)HMM predict
558Phosphoserine(IKK)HMM predict
558Phosphoserine(PKA)HMM predict
569Phosphoserine(IKK)HMM predict
573Phosphothreonine(CDC2)HMM predict
630LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012341
  • Location:chr10 1024348-1053703
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1024164 1024431 267 51
CTCF CD4SISSRdata 1024164 1024431 267 51
CTCF HelaGSE12889 1024190 1024393 203 57
ER MCF7GSE19013 1006192 1007084 892 17711
FOXA1 MCF7GSE15244 1006401 1006911 510 17693
FoxA1 MCF7MACSdata 1007594 1007762 168 16671
GABP HelaGSE8489 1011650 1012977 1327 12035
GABP HelaGSE8489 1021542 1022571 1029 2292
GABP k562GSE8489 1022913 1023137 224 1324
GABP k562GSE8489 1023563 1023866 303 634
Gata2 K562GSE18868 1014772 1015220 448 9353
H3K4me3 colorectalcancer 1022913 1023137 224 1324
H3ac HepG2E 1007416 1007716 300 16783
H3ac HepG2E 1008435 1008757 322 15753
H3ac HepG2E 1011609 1013012 1403 12038
H3ac HepG2E 1022913 1023137 224 1324
H3ac HepG2E 1023563 1025017 1454 59
P300 T0-glioblastomaGSE21026 1023988 1024615 627 47
PHF8 HeLaGSE20725 1023666 1025014 1348 9
PHF8 Hs68plusFBSGSE20725 1023338 1025300 1962 30
RARA MCF7GSE15244 1019886 1020626 740 4093
RARA MCF7GSE15244 1021987 1022571 584 2070
RARG MCF7GSE15244 1006401 1006911 510 17693
RARG MCF7GSE15244 1009602 1010563 961 14266
RARG MCF7GSE15244 1011509 1012794 1285 12197
RARG MCF7GSE15244 1020176 1020626 450 3948
RARG MCF7GSE15244 1022081 1022571 490 2023
USF2 HepG2E 1006401 1006617 216 17840
USF2 HepG2E 1009839 1010528 689 14165
USF2 HepG2E 1011687 1012428 741 12291
hScc1 BcellGSE12603 1023563 1024529 966 303
p130 SenescentGSE19898 1023880 1024699 819 59
p130 shRbQuiescentGSE19898 1023432 1024777 1345 244
p130 shRbSenescentGSE19898 1024073 1024544 471 40
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 1023765 1025100 1335 0
GABP HelaGSE8489 1025370 1025655 285 0
GABP HelaGSE8489 1026687 1027279 592 0
GABP HelaGSE8489 1052618 1053108 490 0
GABP k562GSE8489 1025370 1025655 285 0
GABP k562GSE8489 1025988 1026343 355 0
H3K4me3 colorectalcancer 1024637 1025017 380 0
H3K4me3 colorectalcancer 1025370 1025655 285 0
H3ac HepG2E 1025370 1025655 285 0
H3ac HepG2E 1025988 1026343 355 0
H3ac HepG2E 1026687 1027390 703 0
Nanog hESGSE18292 1049645 1049823 178 0
PHF8 293TGSE20725 1023737 1025024 1287 0
Rb shRbQuiescentGSE19898 1042676 1042829 153 0
TAF k562GSE8489 1025370 1025655 285 0
TFAP2C MCF7GSE21234 1040245 1040629 384 0
hScc1 BcellGSE12603 1046739 1047137 398 0
p130 shRbSenescentGSE19898 1024576 1024787 211 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018