AutismKB 2.0

Annotation Detail for DDX58


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Basic Information Top
Gene Symbol:DDX58 ( DKFZp434J1111,DKFZp686N19181,FLJ13599,RIG-I )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Band: 9p21.1
Quick LinksEntrez ID:23586; OMIM: 609631; Uniprot ID:DDX58_HUMAN; ENSEMBL ID: ENSG00000107201; HGNC ID: 19102
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
375DECH box.
858N6-acetyllysine.
909N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
8Phosphoserine(PKG)HMM predict
8Phosphoserine(PKA)HMM predict
15Phosphotyrosine(EGFR)HMM predict
40Phosphotyrosine(EGFR)HMM predict
40Phosphotyrosine(SRC)HMM predict
86Phosphotyrosine(INSR)HMM predict
197Phosphothreonine(CK2)HMM predict
221N-linkedHMM predict
225N-linkedHMM predict
319Phosphotyrosine(Syk)HMM predict
328O-linkedHMM predict
376N-linkedHMM predict
383Phosphotyrosine(Syk)HMM predict
441Phosphothreonine(PKC)HMM predict
495N-linkedHMM predict
501N-linkedHMM predict
599Phosphoserine(CK1)HMM predict
605Phosphoserine(IKK)HMM predict
730MethylarginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014314
  • Location:chr9 32445300-32516321
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
STAT1 HeLaGSE12783 32515695 32517075 1380 64
TFAP2C MCF7GSE21234 32516037 32516719 682 57
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 32515349 32516112 763 0
Nanog hESGSE18292 32508399 32508572 173 0
SRF k562GSE8489 32455736 32455947 211 0
TFAP2C MCF7GSE21234 32514627 32515219 592 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-146a hsa-mir-146a 5 19596990
hsa-miR-146a* hsa-mir-146a 5 19596990
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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