Annotation Detail for LEMD3
Basic Information Top
| Gene Symbol: | LEMD3 ( MAN1 ) |
|---|---|
| Gene Full Name: | LEM domain containing 3 |
| Band: | 12q14.3 |
| Quick Links | Entrez ID:23592; OMIM: 607844; Uniprot ID:MAN1_HUMAN; ENSEMBL ID: ENSG00000174106; HGNC ID: 28887 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 140 | Phosphoserine. | |
| 141 | Phosphoserine. | |
| 144 | Phosphoserine. | |
| 185 | Phosphoserine. | |
| 187 | Phosphoserine. | |
| 258 | Phosphotyrosine (By similarity). | |
| 259 | Phosphoserine. | |
| 261 | Phosphoserine. | |
| 280 | Phosphoserine. | |
| 331 | Phosphoserine. | |
| 352 | Phosphoserine. | |
| 365 | Phosphothreonine. | |
| 377 | Phosphoserine. | |
| 402 | Phosphoserine. | |
| 777 | Phosphoserine. | |
| 911 | Phosphoserine. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 144 | Phosphoserine | Phospho.ELM 6.0 |
| 258 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 |
| 259 | Phosphoserine. | Swiss-Prot 53.0 |
| 261 | Phosphoserine. | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 13 | Phosphoserine(CK2) | HMM predict |
| 27 | Phosphoserine(CDC2) | HMM predict |
| 61 | N-linked | HMM predict |
| 65 | N-linked | HMM predict |
| 67 | N-linked | HMM predict |
| 69 | N-linked | HMM predict |
| 70 | N-linked | HMM predict |
| 100 | Phosphotyrosine(Jak) | HMM predict |
| 126 | O-linked | HMM predict |
| 144 | Phosphoserine(CK1) | HMM predict |
| 209 | Phosphothreonine | HMM predict |
| 209 | Phosphothreonine(CDC2) | HMM predict |
| 209 | Phosphothreonine(MAPK) | HMM predict |
| 245 | N-linked | HMM predict |
| 257 | N-linked | HMM predict |
| 259 | Phosphoserine(CK2) | HMM predict |
| 259 | Phosphoserine(CK2) | HMM predict |
| 261 | Phosphoserine(CK2) | HMM predict |
| 261 | Phosphoserine | HMM predict |
| 280 | Phosphoserine(CK1) | HMM predict |
| 282 | Phosphoserine(CK1) | HMM predict |
| 291 | Phosphoserine(IKK) | HMM predict |
| 291 | Phosphoserine(CAMK2) | HMM predict |
| 291 | Phosphoserine(PKA) | HMM predict |
| 352 | Phosphoserine(CDC2) | HMM predict |
| 352 | Phosphoserine | HMM predict |
| 385 | Phosphoserine(IKK) | HMM predict |
| 399 | Phosphoserine(ATM) | HMM predict |
| 399 | Phosphoserine(CAMK2) | HMM predict |
| 428 | N-linked | HMM predict |
| 433 | N-linked | HMM predict |
| 439 | N-linked | HMM predict |
| 441 | Phosphotyrosine(Syk) | HMM predict |
| 447 | Phosphoserine(CK2) | HMM predict |
| 463 | Phosphoserine(IKK) | HMM predict |
| 549 | Phosphoserine(CK1) | HMM predict |
| 550 | Phosphoserine(CDC2) | HMM predict |
| 576 | N-linked | HMM predict |
| 604 | N-linked | HMM predict |
| 622 | S-palmitoyl | HMM predict |
| 693 | Phosphotyrosine(Syk) | HMM predict |
| 726 | N-linked | HMM predict |
| 732 | Phosphothreonine(CDK) | HMM predict |
| 777 | Phosphoserine(PKG) | HMM predict |
| 777 | Phosphoserine(CDC2) | HMM predict |
| 777 | Phosphoserine(PKB) | HMM predict |
| 777 | Phosphoserine(PKA) | HMM predict |
| 862 | Phosphothreonine(PKC) | HMM predict |
| 907 | Phosphoserine(ATM) | HMM predict |
| 907 | Phosphoserine(IKK) | HMM predict |
- RefSeq ID: NM_014319
- Location:chr12 63849637-63928373
- strand:+
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ETS1 | Jurkat | GSE17954 | 63849178 | 63849830 | 652 | 134 |
| FOXA1 | MCF7 | GSE15244 | 63849226 | 63849599 | 373 | 225 |
| Nanog | ES | GSE20650 | 63833151 | 63833532 | 381 | 16296 |
| Pol2 | GM12878 | GSE19551 | 63849119 | 63850066 | 947 | 45 |
| RARA | MCF7 | GSE15244 | 63849035 | 63849484 | 449 | 378 |
| RARG | MCF7 | GSE15244 | 63849153 | 63849449 | 296 | 337 |
| Rb | Senescent | GSE19898 | 63849217 | 63849892 | 675 | 83 |
| Rb | shRbSenescence | GSE19898 | 63849248 | 63849685 | 437 | 171 |
| TAF | Hela | GSE8489 | 63848886 | 63849449 | 563 | 470 |
| hScc1 | Bcell | GSE12603 | 63849333 | 63849692 | 359 | 125 |
| p130 | Senescent | GSE19898 | 63849346 | 63849861 | 515 | 34 |
| p130 | shRbSenescent | GSE19898 | 63849322 | 63849857 | 535 | 48 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Fos | K562 | GSE19551 | 63929258 | 63929722 | 464 | 1117 |
| Oct1 | H2O2-Hela | GSE14283 | 63935674 | 63935713 | 39 | 7320 |
| Oct1 | H2O2-Hela | GSE14283 | 63939931 | 63939970 | 39 | 11577 |
| Oct1 | Hela | GSE14283 | 63935675 | 63935714 | 39 | 7321 |
| Oct1 | Hela | GSE14283 | 63939931 | 63939970 | 39 | 11577 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 63849333 | 63850587 | 1254 | 0 |
| FOXA1 | MCF7 | GSE15244 | 63850266 | 63851139 | 873 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 63850814 | 63851321 | 507 | 0 |
| H3K4me3 | colorectal | cancer | 63850554 | 63851442 | 888 | 0 |
| H3ac | HepG2 | E | 63850474 | 63851285 | 811 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 63869015 | 63869055 | 40 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 63885003 | 63885034 | 31 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 63901049 | 63901077 | 28 | 0 |
| Oct1 | Hela | GSE14283 | 63869015 | 63869054 | 39 | 0 |
| Oct1 | Hela | GSE14283 | 63893031 | 63893066 | 35 | 0 |
| PHF8 | 293T | GSE20725 | 63849046 | 63850296 | 1250 | 0 |
| PHF8 | HeLa | GSE20725 | 63849122 | 63850747 | 1625 | 0 |
| PHF8 | Hs68minusFBS | GSE20725 | 63849128 | 63850195 | 1067 | 0 |
| PHF8 | Hs68plusFBS | GSE20725 | 63849203 | 63851036 | 1833 | 0 |
| RARG | MCF7 | GSE15244 | 63850531 | 63851212 | 681 | 0 |
| hScc1 | Bcell | GSE12603 | 63850040 | 63850888 | 848 | 0 |
| hScc1 | CdLS | GSE12603 | 63850142 | 63850787 | 645 | 0 |
Validated miRNA targets