Annotation Detail for AMACR

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Basic Information Top

Gene Symbol:	AMACR ( CBAS4,RACE,RM )
Gene Full Name:	alpha-methylacyl-CoA racemase
Band:	5p13.2
Quick Links	Entrez ID:23600; OMIM: 604489; Uniprot ID:AMACR_HUMAN; ENSEMBL ID: ENSG00000082196,ENSG00000242110; HGNC ID: 451
Relate to Another Database:	SFARIGene; denovo-db

General

Expression

Regulation

Pathways, Diseases and Drugs

PTM

TF binding site

miRNA targets

Cis-NATs

Post Translation Modification

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PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:4 results

Location(AA)	Modification
382	Microbody targeting signal.

Location(AA)	Modification	Resource
144	Phosphotyrosine(SRC)	HMM predict
144	Phosphotyrosine(Syk)	HMM predict
295	Phosphothreonine(CDK)	HMM predict
295	Phosphothreonine	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_014324
Location:chr5 34023662-34043962
strand:-

Upstream the gene:3 results
Downstream the gene:0 results
Inside the gene:15 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
ER	Fulvestrant-MCF7	GSE14664	34046605	34046678	73	2679
TAF	Hela	GSE8489	34044263	34044883	620	611
TAF	k562	GSE8489	34044634	34044883	249	796

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	34033275	34033646	371
CTCF	CD4	SISSRdata	34033275	34033646	371
CTCF	G2	GSE9613	34033243	34033830	587
CTCF	G2	GSE9613	34043554	34044082	528
ER	E2-MCF7	GSE14664	34039211	34039257	46
H3K4me3	colorectal	cancer	34042299	34043518	1219
Myc	K562	GSE19551	34030786	34031275	489
Oct1	H2O2-Hela	GSE14283	34034578	34034607	29
Oct1	Hela	GSE14283	34034578	34034607	29
PHF8	293T	GSE20725	34043365	34044431	1066
PHF8	HeLa	GSE20725	34041860	34044732	2872
RNAII	Tamoxifen-MCF7	GSE14664	34040365	34040426	61
TAF	Hela	GSE8489	34041612	34043739	2127
hScc1	Bcell	GSE12603	34033202	34033575	373
hScc1	Bcell	GSE12603	34043554	34043903	349

Validated miRNA targets

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miR Walk:55 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7a	hsa-let-7a-1	9	21365266
hsa-let-7a	hsa-let-7a-2	11	21365266
hsa-let-7a	hsa-let-7a-3	22	21365266
hsa-let-7a	hsa-let-7a-1	9	19431195
hsa-let-7a	hsa-let-7a-2	11	19431195
hsa-let-7a	hsa-let-7a-3	22	19431195
hsa-let-7a*	hsa-let-7a-1	9	21365266
hsa-let-7a*	hsa-let-7a-3	22	21365266
hsa-let-7a*	hsa-let-7a-1	9	19431195
hsa-let-7a*	hsa-let-7a-3	22	19431195
hsa-let-7b	hsa-let-7b	22	21365266
hsa-let-7b	hsa-let-7b	22	19431195
hsa-let-7b*	hsa-let-7b	22	21365266
hsa-let-7b*	hsa-let-7b	22	19431195
hsa-let-7c	hsa-let-7c	21	21365266
hsa-let-7c	hsa-let-7c	21	19431195
hsa-let-7c*	hsa-let-7c	21	21365266
hsa-let-7c*	hsa-let-7c	21	19431195
hsa-let-7d	hsa-let-7d	9	21365266
hsa-let-7d	hsa-let-7d	9	19431195
hsa-let-7d*	hsa-let-7d	9	21365266
hsa-let-7d*	hsa-let-7d	9	19431195
hsa-let-7e	hsa-let-7e	19	21365266
hsa-let-7e	hsa-let-7e	19	19431195
hsa-let-7e*	hsa-let-7e	19	21365266
hsa-let-7e*	hsa-let-7e	19	19431195
hsa-let-7f	hsa-let-7f-1	9	21365266
hsa-let-7f	hsa-let-7f-2	X	21365266
hsa-let-7f	hsa-let-7f-1	9	19431195
hsa-let-7f	hsa-let-7f-2	X	19431195
hsa-let-7f-1*	hsa-let-7f-1	9	21365266
hsa-let-7f-1*	hsa-let-7f-1	9	19431195
hsa-let-7f-2*	hsa-let-7f-2	X	21365266
hsa-let-7f-2*	hsa-let-7f-2	X	19431195
hsa-let-7g	hsa-let-7g	3	21365266
hsa-let-7g	hsa-let-7g	3	19431195
hsa-let-7g*	hsa-let-7g	3	21365266
hsa-let-7g*	hsa-let-7g	3	19431195
hsa-let-7i	hsa-let-7i	12	21365266
hsa-let-7i	hsa-let-7i	12	19431195
hsa-let-7i*	hsa-let-7i	12	21365266
hsa-let-7i*	hsa-let-7i	12	19431195
hsa-miR-10a	hsa-mir-10a	17	21333734
hsa-miR-10a*	hsa-mir-10a	17	21333734
hsa-miR-10b	hsa-mir-10b	2	21333734
hsa-miR-10b*	hsa-mir-10b	2	21333734
hsa-miR-141	hsa-mir-141	12	20014922
hsa-miR-141*	hsa-mir-141	12	20014922
hsa-miR-183	hsa-mir-183	7	19047896
hsa-miR-183*	hsa-mir-183	7	19047896
hsa-miR-192	hsa-mir-192	11	19047896
hsa-miR-192*	hsa-mir-192	11	19047896
hsa-miR-221	hsa-mir-221	X	20014922
hsa-miR-221*	hsa-mir-221	X	20014922
hsa-miR-346	hsa-mir-346	10	19780716

Cis-Nats regulation

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Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

AutismKB 2.0

Annotation Detail for AMACR

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics