AutismKB 2.0

Annotation Detail for DAPK2


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Basic Information Top
Gene Symbol:DAPK2 ( DRP-1,DRP1,MGC119312 )
Gene Full Name: death-associated protein kinase 2
Band: 15q22.31
Quick LinksEntrez ID:23604; OMIM: NA; Uniprot ID:DAPK2_HUMAN; ENSEMBL ID: ENSG00000035664; HGNC ID: 2675
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
299Phosphoserine (By similarity).
318Phosphoserine; by autocatalysis.
349Phosphoserine.
Location(AA) Modifications Resource
318Phosphoserine (by autocatalysis).Swiss-Prot 53.0
318Phosphoserine (DAPK2)Phospho.ELM 6.0
349Phosphoserine.Swiss-Prot 53.0
349PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
93Phosphotyrosine(Syk)HMM predict
95N-linkedHMM predict
122Phosphoserine(CK1)HMM predict
139Phosphotyrosine(Jak)HMM predict
238N-linkedHMM predict
299Phosphoserine(PKG)HMM predict
363ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014326
  • Location:chr15 61986287-62125573
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 62125663 62125997 334 257
CTCF CD4SISSRdata 62125663 62125997 334 257
CTCF G2GSE9613 62125300 62126228 928 191
ER E2-MCF7GSE14664 62133815 62133848 33 8258
TFAP2C MCF7GSE21234 62129485 62130269 784 4304
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 61975351 61976740 1389 10242
CTCF CD4GSE12889 61970226 61970558 332 15896
CTCF CD4SISSRdata 61970226 61970558 332 15896
CTCF G2GSE9613 61970202 61970927 725 15723
CTCF G2GSE9613 61984739 61984990 251 1423
ER Fulvestrant-MCF7GSE14664 61967027 61967090 63 19229
ER MCF7GSE19013 61975777 61976649 872 10075
NFkBII GM12878GSE19485 61975113 61976923 1810 10270
NFkBII GM12892GSE19485 61975242 61976908 1666 10213
NRSF mAbJurkat 61978157 61978418 261 8000
P300 T30-glioblastomaGSE21026 61975417 61976945 1528 10107
RARA MCF7GSE15244 61975399 61976345 946 10416
Rb SenescentGSE19898 61970305 61970531 226 15870
TAF HelaGSE8489 61976722 61977111 389 9371
hScc1 BcellGSE12603 61970202 61970927 725 15723
hScc1 BcellGSE12603 61972104 61972516 412 13978
hScc1 CdLSGSE12603 61970202 61970681 479 15846
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 62089797 62090534 737 0
CTCF CD4GSE12889 62024509 62024832 323 0
CTCF CD4GSE12889 62062610 62062783 173 0
CTCF CD4GSE12889 62090075 62090372 297 0
CTCF CD4SISSRdata 62024509 62024832 323 0
CTCF CD4SISSRdata 62062610 62062783 173 0
CTCF CD4SISSRdata 62090075 62090372 297 0
CTCF G2GSE9613 61987513 61988224 711 0
CTCF G2GSE9613 61995668 61996051 383 0
CTCF G2GSE9613 62024548 62025102 554 0
CTCF G2GSE9613 62070295 62070582 287 0
CTCF G2GSE9613 62077409 62078061 652 0
ER Fulvestrant-MCF7GSE14664 62023161 62023215 54 0
ER Fulvestrant-MCF7GSE14664 62113144 62113195 51 0
ER MCF7GSE19013 61992927 61993596 669 0
ER MCF7GSE19013 61997043 61997511 468 0
ER MCF7GSE19013 62024899 62025741 842 0
FOXA1 MCF7GSE15244 62004503 62005694 1191 0
FOXA1 MCF7GSE15244 62024584 62025588 1004 0
FOXA1 MCF7GSE15244 62098983 62099583 600 0
FOXA1 eGFPGSE10845 62004503 62005694 1191 0
FOXA1 eGFPGSE10845 62024584 62025588 1004 0
FOXA1 eGFPGSE10845 62098983 62099583 600 0
Fos K562GSE19551 62118234 62118638 404 0
FoxA1 MCF7MACSdata 62025119 62025331 212 0
FoxA1 MCF7MACSdata 62096340 62096613 273 0
FoxA1 MCF7MACSdata 62098946 62099431 485 0
Myc K562GSE19551 62083550 62084341 791 0
Nanog hESGSE18292 61994886 61995053 167 0
Oct1 H2O2-HelaGSE14283 62082090 62082129 39 0
Oct1 H2O2-HelaGSE14283 62113021 62113050 29 0
Oct1 H2O2-HelaGSE14283 62116785 62116815 30 0
Oct1 HelaGSE14283 62011769 62011813 44 0
Oct1 HelaGSE14283 62023160 62023207 47 0
Oct1 HelaGSE14283 62023364 62023421 57 0
Oct1 HelaGSE14283 62027692 62027728 36 0
Oct1 HelaGSE14283 62052617 62052685 68 0
Oct1 HelaGSE14283 62075766 62075795 29 0
Oct1 HelaGSE14283 62082090 62082129 39 0
Oct1 HelaGSE14283 62113013 62113050 37 0
P300 T30-glioblastomaGSE21026 62089739 62090645 906 0
TFAP2C MCF7GSE21234 61992935 61993713 778 0
TFAP2C MCF7GSE21234 62024585 62025580 995 0
TFAP2C MCF7GSE21234 62076006 62076615 609 0
TFAP2C MCF7GSE21234 62083831 62084343 512 0
hScc1 BcellGSE12603 62007529 62007748 219 0
hScc1 BcellGSE12603 62024222 62025102 880 0
hScc1 BcellGSE12603 62062299 62063069 770 0
hScc1 BcellGSE12603 62064517 62064769 252 0
hScc1 BcellGSE12603 62089853 62090364 511 0
hScc1 BcellGSE12603 62105271 62105452 181 0
hScc1 BcellGSE12603 62124725 62126193 1468 0
hScc1 CdLSGSE12603 62024416 62025102 686 0
hScc1 CdLSGSE12603 62089750 62090364 614 0
p130 SenescentGSE19898 62018856 62019284 428 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8933 mRNA chr15 62007525 62015205 27 mRNA DAPK2 chr15 61986288 62125574Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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