AutismKB 2.0

Annotation Detail for SH3BP1


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Basic Information Top
Gene Symbol:SH3BP1 ( ARHGAP43 )
Gene Full Name: SH3-domain binding protein 1
Band: 22q13.1
Quick LinksEntrez ID:23616; OMIM: NA; Uniprot ID:3BP1_HUMAN; ENSEMBL ID: ENSG00000100092; HGNC ID: 10824
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
544Phosphoserine.
550Phosphoserine.
625SH3-binding (By similarity).
626Phosphothreonine.
653Phosphoserine (By similarity).
Location(AA) Modifications Resource
Location(AA) Modification Resource
131Phosphoserine(CK1)HMM predict
154Phosphothreonine(PKC)HMM predict
160Phosphoserine(PKG)HMM predict
160Phosphoserine(ATM)HMM predict
169Phosphoserine(ATM)HMM predict
175Phosphoserine(ATM)HMM predict
175O-linkedHMM predict
180Phosphoserine(IKK)HMM predict
190Phosphothreonine(PKC)HMM predict
243Phosphoserine(IKK)HMM predict
326Phosphothreonine(PKA)HMM predict
329Phosphoserine(ATM)HMM predict
365SulfotyrosineHMM predict
373Phosphoserine(PKG)HMM predict
448Phosphoserine(CK2)HMM predict
501O-linkedHMM predict
501O-linkedHMM predict
501O-linkedHMM predict
506O-linkedHMM predict
506Phosphothreonine(MAPK)HMM predict
506Phosphothreonine(CDK)HMM predict
510O-linkedHMM predict
510O-linkedHMM predict
536Phosphoserine(IKK)HMM predict
544Phosphoserine(CDC2)HMM predict
548O-linkedHMM predict
548O-linkedHMM predict
548Phosphothreonine(PKC)HMM predict
550O-linkedHMM predict
550Phosphoserine(CDC2)HMM predict
550Phosphoserine(IKK)HMM predict
574O-linkedHMM predict
574O-linkedHMM predict
581O-linkedHMM predict
583O-linkedHMM predict
585O-linkedHMM predict
586Phosphoserine(IKK)HMM predict
586Phosphoserine(PKA)HMM predict
586O-linkedHMM predict
586Phosphoserine(ATM)HMM predict
596O-linkedHMM predict
598Phosphoserine(CDK)HMM predict
598Phosphoserine(CDC2)HMM predict
598Phosphoserine(IKK)HMM predict
598O-linkedHMM predict
601Phosphothreonine(CDK)HMM predict
626Phosphothreonine(CDK)HMM predict
635O-linkedHMM predict
638Phosphoserine(CDK)HMM predict
638Phosphoserine(IKK)HMM predict
638Phosphoserine(CDC2)HMM predict
641O-linkedHMM predict
641Phosphoserine(CDK)HMM predict
641Phosphoserine(MAPK)HMM predict
641Phosphoserine(CDC2)HMM predict
643Phosphoserine(CDK)HMM predict
643Phosphoserine(CDC2)HMM predict
643Phosphoserine(IKK)HMM predict
646Phosphoserine(CDC2)HMM predict
646Phosphoserine(MAPK)HMM predict
651Phosphoserine(MAPK)HMM predict
651Phosphoserine(CDC2)HMM predict
653Phosphoserine(CDC2)HMM predict
653Phosphoserine(IKK)HMM predict
656Phosphoserine(IKK)HMM predict
658Phosphoserine(IKK)HMM predict
679O-linkedHMM predict
683Phosphothreonine(MAPK)HMM predict
689ProlineHMM predict
695Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018957
  • Location:chr22 36365629-36381994
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb SenescentGSE19898 36365214 36365443 229 301
p130 SenescentGSE19898 36364289 36364564 275 1203
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 36369222 36369633 411 0
CTCF CD4SISSRdata 36369222 36369633 411 0
CTCF G2GSE9613 36365505 36365823 318 0
CTCF G2GSE9613 36369149 36369884 735 0
hScc1 BcellGSE12603 36365403 36366093 690 0
hScc1 BcellGSE12603 36369111 36369884 773 0
hScc1 BcellGSE12603 36381187 36381636 449 0
hScc1 CdLSGSE12603 36369149 36369714 565 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
17449 mRNA SH3BP1 chr22 36361877 36376545 537 mRNA chr22 36362338 36378884Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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