AutismKB 2.0

Annotation Detail for PPP1R15A


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Basic Information Top
Gene Symbol:PPP1R15A ( GADD34 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 15A
Band: 19q13.2
Quick LinksEntrez ID:23645; OMIM: 611048; Uniprot ID:PR15A_HUMAN; ENSEMBL ID: ENSG00000087074; HGNC ID: 14375
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
262Phosphotyrosine.
264Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_014330
  • Location:chr19 54067489-54071125
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
HIF1 HypoHepG2 54067231 54067656 425 46
PHF8 293TGSE20725 54066993 54067924 931 31
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 54067231 54068423 1192 0
Gata1 K562GSE18868 54067798 54069171 1373 0
Gata2 K562GSE18868 54067163 54070174 3011 0
H3K4me3 colorectalcancer 54069380 54069959 579 0
NFkBII GM12878GSE19485 54069795 54071329 1534 0
PHF8 HeLaGSE20725 54067040 54068168 1128 0
Pol2 GM12878GSE19551 54067174 54070139 2965 0
TAF HelaGSE8489 54067554 54068387 833 0
TAF k562GSE8489 54067456 54069959 2503 0
USF1 HepG2E 54069273 54069789 516 0
hScc1 BcellGSE12603 54067417 54068565 1148 0
hScc1 BcellGSE12603 54070561 54071118 557 0
p130 SenescentGSE19898 54067219 54067778 559 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018