AutismKB 2.0

Annotation Detail for TMEFF2


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Basic Information Top
Gene Symbol:TMEFF2 ( CT120.2,HPP1,TENB2,TPEF,TR )
Gene Full Name: transmembrane protein with EGF-like and two follistatin-like domains 2
Band: 2q32.3
Quick LinksEntrez ID:23671; OMIM: 605734; Uniprot ID:TEFF2_HUMAN; ENSEMBL ID: ENSG00000144339; HGNC ID: 11867
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
55N-linked (GlcNAc...) (Potential).
230N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
55N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
230N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
12Phosphoserine(IKK)HMM predict
55N-linkedHMM predict
91S-palmitoylHMM predict
105Phosphoserine(IKK)HMM predict
155Phosphoserine(ATM)HMM predict
155Phosphoserine(IKK)HMM predict
230N-linkedHMM predict
237O-linkedHMM predict
247SulfotyrosineHMM predict
305Phosphotyrosine(INSR)HMM predict
305Phosphotyrosine(Syk)HMM predict
340S-palmitoylHMM predict
365N-linkedHMM predict
366O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016192
  • Location:chr2 192522993-192767888
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 192767559 192768489 930 136
H3K27me3 colorectalcancer 192768525 192769818 1293 1283
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NFkBII GM12892GSE19485 192505744 192507107 1363 16568
NFkBII GM15510GSE19485 192505762 192507086 1324 16570
NFkBII GM18526GSE19485 192505591 192507142 1551 16627
STAT1 HeLaGSE12783 192511489 192512475 986 11012
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 192735413 192735695 282 0
CTCF CD4SISSRdata 192735413 192735695 282 0
CTCF G2GSE9613 192735334 192735750 416 0
H3K27me3 colorectalcancer 192765124 192765625 501 0
H3K27me3 colorectalcancer 192765914 192767780 1866 0
Nanog ESGSE20650 192552461 192552735 274 0
Nanog hESGSE18292 192735464 192735851 387 0
P300 T0-glioblastomaGSE21026 192549182 192550019 837 0
PAX3-FKHR Rh4GSE19063 192728081 192729280 1199 0
Stat6 IL-4-hr1GSE17850 192558652 192559204 552 0
hScc1 BcellGSE12603 192735165 192735785 620 0
hScc1 CdLSGSE12603 192735027 192735964 937 0
hScc1 G2GSE9613 192734781 192735750 969 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018