AutismKB 2.0

Annotation Detail for FLRT2


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Basic Information Top
Gene Symbol:FLRT2 ( KIAA0405 )
Gene Full Name: fibronectin leucine rich transmembrane protein 2
Band: 14q31.3
Quick LinksEntrez ID:23768; OMIM: 604807; Uniprot ID:FLRT2_HUMAN; ENSEMBL ID: ENSG00000185070; HGNC ID: 3761
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
202N-linked (GlcNAc...).
298N-linked (GlcNAc...) (Potential).
433N-linked (GlcNAc...) (Potential).
521N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
202N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
298N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
433N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
521N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
5Phosphothreonine(PKC)HMM predict
55Phosphothreonine(PKC)HMM predict
144Phosphoserine(CK1)HMM predict
202N-linkedHMM predict
205Phosphoserine(CK1)HMM predict
241Phosphoserine(PKG)HMM predict
375O-linkedHMM predict
378Phosphoserine(CDC2)HMM predict
378Phosphoserine(IKK)HMM predict
378O-linkedHMM predict
381O-linkedHMM predict
390N-linkedHMM predict
392O-linkedHMM predict
392O-linkedHMM predict
394O-linkedHMM predict
396Phosphothreonine(CDK)HMM predict
399Phosphothreonine(MAPK)HMM predict
399O-linkedHMM predict
401O-linkedHMM predict
402O-linkedHMM predict
403O-linkedHMM predict
418Phosphothreonine(PKA)HMM predict
433N-linkedHMM predict
488Phosphothreonine(PKC)HMM predict
521N-linkedHMM predict
524N-linkedHMM predict
528O-linkedHMM predict
528O-linkedHMM predict
536Phosphoserine(IKK)HMM predict
574Phosphoserine(ATM)HMM predict
598Phosphoserine(IKK)HMM predict
635N-linkedHMM predict
647TyrosineHMM predict
648CysteineHMM predict
649N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_013231
  • Location:chr14 85066240-85164021
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 85047266 85047353 87 18931
CTCF G2GSE9613 85065889 85066139 250 227
Oct4 hESGSE17917 85047243 85047390 147 18924
RNAII Tamoxifen-MCF7GSE14664 85055897 85055981 84 10302
Stat6 IL-4-hr4GSE17850 85065868 85066335 467 139
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 85176489 85176521 32 12484
Oct1 HelaGSE14283 85176489 85176521 32 12484
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 85143475 85144190 715 0
CTCF G2GSE9613 85069346 85069487 141 0
H3ac HepG2E 85070146 85070887 741 0
Oct1 HelaGSE14283 85103027 85103068 41 0
P300 T30-glioblastomaGSE21026 85101819 85102585 766 0
P300 T30-glioblastomaGSE21026 85123081 85124401 1320 0
P300 T30-glioblastomaGSE21026 85143488 85144369 881 0
RARA MCF7GSE15244 85123409 85123936 527 0
RARG MCF7GSE15244 85158105 85159098 993 0
Rb SenescentGSE19898 85069080 85069510 430 0
p130 shRbSenescentGSE19898 85069105 85069651 546 0
p63 keratinocytesGSE17611 85092090 85093014 924 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8212 mRNA FLRT2 chr14 85066240 85164022 391 mRNA chr14 85064416 85067856Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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