AutismKB 2.0

Annotation Detail for ARHGAP8


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Basic Information Top
Gene Symbol:ARHGAP8 ( BPGAP1,FLJ20185,PP610 )
Gene Full Name: Rho GTPase activating protein 8
Band: 22q13.31
Quick LinksEntrez ID:23779; OMIM: 609405; Uniprot ID:RHG08_HUMAN; ENSEMBL ID: ENSG00000241484; HGNC ID: 677
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
448Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
32Phosphothreonine(PKC)HMM predict
40N-linkedHMM predict
44N-linkedHMM predict
66Phosphoserine(CK1)HMM predict
319SulfotyrosineHMM predict
319Phosphotyrosine(INSR)HMM predict
324SulfotyrosineHMM predict
348Phosphotyrosine(Syk)HMM predict
460PhosphothreonineHMM predict
460Phosphothreonine(MAPK)HMM predict
466Phosphothreonine(MAPK)HMM predict
475O-linkedHMM predict
521Phosphoserine(CAMK2)HMM predict
521Phosphoserine(PKG)HMM predict
521Phosphoserine(PKA)HMM predict
524Phosphothreonine(PKC)HMM predict
543SulfotyrosineHMM predict
543Phosphotyrosine(INSR)HMM predict
600Phosphotyrosine(SRC)HMM predict
623N-linkedHMM predict
626N-linkedHMM predict
662Phosphotyrosine(Syk)HMM predict
696O-linkedHMM predict
709Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001017526
  • Location:chr22 43527101-43637325
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
P300 T30-glioblastomaGSE21026 43644325 43645038 713 7356
hScc1 BcellGSE12603 43640396 43640592 196 3169
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 43635923 43636094 171 0
CTCF CD4SISSRdata 43635923 43636094 171 0
CTCF G2GSE9613 43594666 43595607 941 0
ETS1 JurkatGSE17954 43555935 43556386 451 0
P300 T30-glioblastomaGSE21026 43628398 43629204 806 0
RARA MCF7GSE15244 43528075 43528827 752 0
RARA MCF7GSE15244 43530023 43530843 820 0
RARG MCF7GSE15244 43528075 43528827 752 0
RARG MCF7GSE15244 43530174 43530884 710 0
TFAP2C MCF7GSE21234 43527981 43528883 902 0
TFAP2C MCF7GSE21234 43533947 43534536 589 0
TFAP2C MCF7GSE21234 43595110 43595501 391 0
hScc1 BcellGSE12603 43539807 43540821 1014 0
hScc1 BcellGSE12603 43570097 43570639 542 0
hScc1 BcellGSE12603 43574996 43575695 699 0
hScc1 BcellGSE12603 43595315 43595668 353 0
hScc1 CdLSGSE12603 43595242 43595668 426 0
hScc1 G2GSE9613 43595087 43595668 581 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018