AutismKB 2.0

Annotation Detail for ALOX12


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Basic Information Top
Gene Symbol:ALOX12 ( 12-LOX,12S-LOX,LOG12 )
Gene Full Name: arachidonate 12-lipoxygenase
Band: 17p13.1
Quick LinksEntrez ID:239; OMIM: 152391; Uniprot ID:LOX12_HUMAN; ENSEMBL ID: ENSG00000108839; HGNC ID: 429
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
107Phosphoserine(CK1)HMM predict
246Phosphoserine(PKB)HMM predict
246Phosphoserine(IKK)HMM predict
246Phosphoserine(PKA)HMM predict
270N-linkedHMM predict
295Phosphotyrosine(Syk)HMM predict
322N-linkedHMM predict
324O-linkedHMM predict
325Phosphoserine(CDC2)HMM predict
325O-linkedHMM predict
325Phosphoserine(IKK)HMM predict
327Phosphothreonine(MAPK)HMM predict
329O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000697
  • Location:chr17 6840127-6854775
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 6823356 6823390 34 16755
TFAP2C MCF7GSE21234 6822888 6823168 280 17100
hScc1 BcellGSE12603 6839690 6840032 342 267
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 6855035 6855469 434 477
H3ac HepG2E 6854926 6855469 543 422
USF1 HepG2E 6854926 6855469 543 422
USF2 HepG2E 6854926 6855469 543 422
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 6848824 6849267 443 0
CTCF CD4SISSRdata 6848824 6849267 443 0
CTCF G2GSE9613 6845615 6845885 270 0
CTCF G2GSE9613 6848646 6849346 700 0
Fos K562GSE19551 6842843 6843722 879 0
Myc hESGSE17917 6839988 6840309 321 0
Nanog hESGSE18292 6848940 6849094 154 0
Oct1 HelaGSE14283 6842550 6842592 42 0
RARG MCF7GSE15244 6849236 6849490 254 0
USF1 HepG2E 6849236 6849490 254 0
USF1 HepG2E 6853806 6854590 784 0
hScc1 BcellGSE12603 6842462 6842751 289 0
hScc1 BcellGSE12603 6848718 6849490 772 0
hScc1 CdLSGSE12603 6848606 6849200 594 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
10558 mRNA ALOX12 chr17 6840127 6854776 281 EST chr17 6843281 6856374Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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