AutismKB 2.0

Annotation Detail for PANX1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PANX1 ( MGC21309,MRS1,PX1,UNQ2529 )
Gene Full Name: pannexin 1
Band: 11q21
Quick LinksEntrez ID:24145; OMIM: 608420; Uniprot ID:PANX1_HUMAN; ENSEMBL ID: ENSG00000110218; HGNC ID: 8599
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
255N-linked (GlcNAc...).
Location(AA) Modifications Resource
Location(AA) Modification Resource
255N-linkedHMM predict
303Phosphothreonine(PKA)HMM predict
325Phosphotyrosine(INSR)HMM predict
325Phosphotyrosine(Syk)HMM predict
338N-linkedHMM predict
394N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_015368
  • Location:chr11 93501741-93554782
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 93501057 93501696 639 365
Fos K562GSE19551 93498219 93498574 355 3345
H3ac HepG2E 93501057 93501341 284 543
LIN9 G0GSE7516 93501057 93501696 639 365
LIN9 SGSE7516 93501057 93501561 504 433
Nanog hESGSE18292 93492529 93492980 451 8987
Oct1 H2O2-HelaGSE14283 93491749 93491776 27 9979
Oct1 HelaGSE14283 93491730 93491837 107 9958
Oct4 hESGSE21916 93501072 93501882 810 265
PHF8 293TGSE20725 93501060 93502303 1243 60
p130 QuiescentGSE19898 93501202 93501631 429 325
p130 SenescentGSE19898 93501060 93501769 709 327
p130 shRbQuiescentGSE19898 93501112 93501694 582 339
p130 shRbSenescentGSE19898 93501090 93501663 573 365
p130 G0GSE7516 93501057 93501696 639 365
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 93556644 93556891 247 1985
CTCF CD4SISSRdata 93556644 93556891 247 1985
Oct4 hESGSE17917 93556519 93557006 487 1980
hScc1 BcellGSE12603 93556492 93556984 492 1956
hScc1 CdLSGSE12603 93556456 93556984 528 1938
hScc1 G2GSE9613 93556492 93557134 642 2031
p130 QuiescentGSE19898 93565282 93565516 234 10617
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 93544490 93544782 292 0
CTCF CD4SISSRdata 93544490 93544782 292 0
Fos K562GSE19551 93524896 93525763 867 0
GABP HelaGSE8489 93512006 93512269 263 0
H3K4me2 HCT116GSE10453 93502457 93504001 1544 0
H3ac HepG2E 93502298 93504716 2418 0
Myc K562GSE19551 93509051 93509398 347 0
Oct1 HelaGSE14283 93547652 93547689 37 0
PHF8 HeLaGSE20725 93501254 93502467 1213 0
Rb QuiescentGSE19898 93501716 93501866 150 0
Rb SenescentGSE19898 93501937 93502139 202 0
TFAP2C MCF7GSE21234 93505024 93505491 467 0
TFAP2C MCF7GSE21234 93516983 93517551 568 0
USF1 HepG2E 93502262 93504635 2373 0
USF2 HepG2E 93502421 93503391 970 0
USF2 HepG2E 93503856 93504238 382 0
hScc1 BcellGSE12603 93517380 93517790 410 0
hScc1 CdLSGSE12603 93544474 93544917 443 0
hScc1 G2GSE9613 93544582 93544917 335 0
p130 QuiescentGSE19898 93502020 93502487 467 0
p130 QuiescentGSE19898 93503610 93503879 269 0
p130 SenescentGSE19898 93501928 93502341 413 0
p130 shRbQuiescentGSE19898 93502007 93502756 749 0
p130 shRbSenescentGSE19898 93501975 93502320 345 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1078 Unknown pSILAC miR-16 PANX1 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000110218 n_a n_a n_a "lymphoblast, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5041 mRNA PANX1 chr11 93501741 93554783 73 EST chr11 93439931 93502214Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved