AutismKB 2.0

Annotation Detail for ALOX12B


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Basic Information Top
Gene Symbol:ALOX12B ( 12R-LOX )
Gene Full Name: arachidonate 12-lipoxygenase, 12R type
Band: 17p13.1
Quick LinksEntrez ID:242; OMIM: 603741; Uniprot ID:LX12B_HUMAN; ENSEMBL ID: ENSG00000179477; HGNC ID: 430
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
102SulfotyrosineHMM predict
248Phosphoserine(PKG)HMM predict
281Phosphothreonine(PKA)HMM predict
359Phosphoserine(ATM)HMM predict
361Phosphothreonine(MAPK)HMM predict
433Phosphotyrosine(Jak)HMM predict
472Phosphoserine(PKG)HMM predict
476Phosphotyrosine(INSR)HMM predict
476Phosphotyrosine(SRC)HMM predict
573O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001139
  • Location:chr17 7916710-7931745
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 7931731 7932410 679 325
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 7913052 7913352 300 3509
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 7917623 7917973 350 0
CTCF CD4SISSRdata 7917623 7917973 350 0
CTCF HelaGSE12889 7917758 7918041 283 0
CTCF G2GSE9613 7917437 7918078 641 0
CTCF G2GSE9613 7923344 7924719 1375 0
KLF4 hESGSE17917 7923380 7923611 231 0
RARG MCF7GSE15244 7923344 7923536 192 0
hScc1 BcellGSE12603 7917724 7918078 354 0
hScc1 BcellGSE12603 7923424 7924459 1035 0
hScc1 CdLSGSE12603 7917724 7918042 318 0
hScc1 CdLSGSE12603 7923642 7924971 1329 0
hScc1 G2GSE9613 7923344 7925008 1664 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
10605 mRNA chr17 7923524 7925606 582 mRNA ALOX12B chr17 7916709 7931746Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018